Total synthesis of a functional designer eukaryotic chromosome N Annaluru, H Muller, LA Mitchell, S Ramalingam, G Stracquadanio, ... science 344 (6179), 55-58, 2014 | 657 | 2014 |
Design of a synthetic yeast genome SM Richardson, LA Mitchell, G Stracquadanio, K Yang, JS Dymond, ... Science 355 (6329), 1040-1044, 2017 | 585 | 2017 |
“Perfect” designer chromosome V and behavior of a ring derivative ZX Xie, BZ Li, LA Mitchell, Y Wu, X Qi, Z Jin, B Jia, X Wang, BX Zeng, ... Science 355 (6329), eaaf4704, 2017 | 282 | 2017 |
Bug mapping and fitness testing of chemically synthesized chromosome X Y Wu, BZ Li, M Zhao, LA Mitchell, ZX Xie, QH Lin, X Wang, WH Xiao, ... Science 355 (6329), eaaf4706, 2017 | 262 | 2017 |
Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond LA Mitchell, A Wang, G Stracquadanio, Z Kuang, X Wang, K Yang, ... Science 355 (6329), eaaf4831, 2017 | 243 | 2017 |
Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome Y Shen, Y Wang, T Chen, F Gao, J Gong, D Abramczyk, R Walker, H Zhao, ... Science 355 (6329), eaaf4791, 2017 | 236 | 2017 |
The importance of p53 pathway genetics in inherited and somatic cancer genomes G Stracquadanio, X Wang, M Wallace, A Grawenda, P Zhang, J Hewitt, ... Nature Reviews Cancer 16 (4), 251--265, 2016 | 166 | 2016 |
SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes Y Shen, G Stracquadanio, Y Wang, K Yang, LA Mitchell, Y Xue, Y Cai, ... Genome research 26 (1), 36-49, 2016 | 157 | 2016 |
Yeast Golden Gate (yGG) for the Efficient Assembly of S. cerevisiae Transcription Units N Agmon, LA Mitchell, Y Cai, S Ikushima, J Chuang, A Zheng, WJ Choi, ... ACS synthetic biology 4 (7), 853-859, 2015 | 92 | 2015 |
Intrinsic biocontainment: multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes Y Cai, N Agmon, WJ Choi, A Ubide, G Stracquadanio, K Caravelli, H Hao, ... Proceedings of the National Academy of Sciences 112 (6), 1803-1808, 2015 | 77 | 2015 |
Technological challenges and milestones for writing genomes N Ostrov, J Beal, T Ellis, DB Gordon, BJ Karas, HH Lee, SC Lenaghan, ... Science 366 (6463), 310-312, 2019 | 71 | 2019 |
Generalized pattern search algorithm for peptide structure prediction G Nicosia, G Stracquadanio Biophysical journal 95 (10), 4988-4999, 2008 | 57 | 2008 |
RADOM, an Efficient In Vivo Method for Assembling Designed DNA Fragments up to 10 kb Long in Saccharomyces cerevisiae Q Lin, B Jia, LA Mitchell, J Luo, K Yang, KI Zeller, W Zhang, Z Xu, ... ACS synthetic biology 4 (3), 213-220, 2015 | 49 | 2015 |
Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression, and drug response P Zhang, I Kitchen-Smith, L Xiong, G Stracquadanio, K Brown, PH Richter, ... Cancer research 81 (7), 1667-1680, 2021 | 42 | 2021 |
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions Y Zhao, C Coelho, AL Hughes, L Lazar-Stefanita, S Yang, AN Brooks, ... Cell 186 (24), 5220-5236. e16, 2023 | 41 | 2023 |
An advanced clonal selection algorithm with ad-hoc network-based hypermutation operators for synthesis of topology and sizing of analog electrical circuits A Ciccazzo, P Conca, G Nicosia, G Stracquadanio Artificial Immune Systems: 7th International Conference, ICARIS 2008, Phuket …, 2008 | 38 | 2008 |
Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae N Agmon, Z Tang, K Yang, B Sutter, S Ikushima, Y Cai, K Caravelli, ... Proceedings of the National Academy of Sciences 114 (8), E1470-E1479, 2017 | 34 | 2017 |
Design of robust space trajectories G Stracquadanio, A La Ferla, M De Felice, G Nicosia International Conference on Innovative Techniques and Applications of …, 2011 | 21 | 2011 |
Computational energy-based redesign of robust proteins G Stracquadanio, G Nicosia Computers & chemical engineering 35 (3), 464-473, 2011 | 21 | 2011 |
Analysis and optimization of c3 photosynthetic carbon metabolism G Stracquadanio, R Umeton, A Papini, P Lio, G Nicosia 2010 IEEE International Conference on BioInformatics and BioEngineering, 44-51, 2010 | 21 | 2010 |