| Roles of eukaryotic topoisomerases in transcription, replication and genomic stability Y Pommier, Y Sun, SN Huang, JL Nitiss Nature reviews Molecular cell biology 17 (11), 703-721, 2016 | 860 | 2016 |
| Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress A Thomas, N Takahashi, VN Rajapakse, X Zhang, Y Sun, M Ceribelli, ... Cancer Cell 39 (4), 566-579. e7, 2021 | 130 | 2021 |
| A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation Y Sun, LM Miller Jenkins, YP Su, KC Nitiss, JL Nitiss, Y Pommier Science Advances 6 (46), eaba6290, 2020 | 119* | 2020 |
| The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin DB Krastev*, S Li*, Y Sun*, AJ Wicks, G Hoslett, D Weekes, LM Badder, ... Nature Cell Biology, 1-12, 2022 | 83 | 2022 |
| Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC) Y Sun*, S Saha*, W Wang, LK Saha, SYN Huang, Y Pommier DNA repair 89, 102837, 2020 | 74 | 2020 |
| Multiview confocal super-resolution microscopy Y Wu, X Han, Y Su, M Glidewell, JS Daniels, J Liu, T Sengupta, ... Nature 600 (7888), 279-284, 2021 | 66 | 2021 |
| Debulking of topoisomerase DNA-protein crosslinks (TOP-DPC) by the proteasome, non-proteasomal and non-proteolytic pathways Y Sun, LK Saha, S Saha, U Jo, Y Pommier DNA repair 94, 102926, 2020 | 63 | 2020 |
| Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity N Sciascia, W Wu, D Zong, Y Sun, N Wong, S John, D Wangsa, T Ried, ... Elife 9, e53447, 2020 | 38 | 2020 |
| Detection of topoisomerase covalent complexes in eukaryotic cells J Anand, Y Sun, Y Zhao, KC Nitiss, JL Nitiss DNA topoisomerases: Methods and protocols, 283-299, 2018 | 37 | 2018 |
| PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation Y Sun, J Chen, SN Huang, YP Su, W Wang, K Agama, S Saha, ... Nature communications 12 (1), 5010, 2021 | 34 | 2021 |
| DNA and RNA cleavage complexes and repair pathway for TOP3B RNA-and DNA-protein crosslinks S Saha, Y Sun, SN Huang, SA Baechler, LS Pongor, K Agama, U Jo, ... Cell reports 33 (13), 2020 | 34* | 2020 |
| Topoisomerase assays JL Nitiss, K Kiianitsa, Y Sun, KC Nitiss, N Maizels Current protocols 1 (10), e250, 2021 | 29 | 2021 |
| Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast N Stantial, A Rogojina, M Gilbertson, Y Sun, H Miles, S Shaltz, J Berger, ... Proceedings of the National Academy of Sciences 117 (43), 26876-26884, 2020 | 23 | 2020 |
| TOP1-DNA trapping by exatecan and combination therapy with ATR inhibitor U Jo, Y Murai, KK Agama, Y Sun, LK Saha, X Yang, Y Arakawa, S Gayle, ... Molecular cancer therapeutics, molcanther. 1000.2021, 2022 | 22 | 2022 |
| Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5 S Saha, X Yang, SN Huang, K Agama, SA Baechler, Y Sun, H Zhang, ... Cell Reports 40 (2), 111067, 2022 | 21 | 2022 |
| A polymer index-matched to water enables diverse applications in fluorescence microscopy X Han, Y Su, H White, KM O'Neill, NY Morgan, R Christensen, D Potarazu, ... Lab on a Chip 21 (8), 1549-1562, 2021 | 18 | 2021 |
| SUMO: A Swiss Army Knife for Eukaryotic Topoisomerases Y Sun, JL Nitiss, Y Pommier Frontiers in Molecular Biosciences, 308, 2022 | 13 | 2022 |
| The indenoisoquinoline LMP517: A novel antitumor agent targeting both TOP1 and TOP2 L Marzi, Y Sun, SN Huang, A James, S Difilippantonio, Y Pommier Molecular cancer therapeutics 19 (8), 1589-1597, 2020 | 13 | 2020 |
| Autophagy-dependent sensitization of triple-negative breast cancer models to topoisomerase II poisons by inhibition of the nucleosome remodeling factor L Tyutyunyk-Massey, Y Sun, N Dao, H Ngo, M Dammalapati, ... Molecular Cancer Research 19 (8), 1338-1349, 2021 | 10 | 2021 |
| Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex Y Sun, SA Baechler, X Zhang, S Kumar, VM Factor, Y Arakawa, CH Chau, ... Nature Communications 14 (1), 3762, 2023 | 8 | 2023 |
