The Yersinia Virulence Effector YopM Binds Caspase-1 to Arrest Inflammasome Assembly and Processing CN LaRock, BT Cookson Cell Host & Microbe 12 (6), 799-805, 2012 | 245 | 2012 |
IL-1β is an innate immune sensor of microbial proteolysis CN LaRock, J Todd, DL LaRock, J Olson, AJ O’Donoghue, ... Science Immunology 1 (2), eaah3539, 2016 | 156* | 2016 |
The Globally Disseminated M1T1 Clone of Group A Streptococcus Evades Autophagy for Intracellular Replication TC Barnett, D Liebl, LM Seymour, CM Gillen, JY Lim, CN LaRock, ... Cell host & microbe 14 (6), 675-682, 2013 | 151 | 2013 |
Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells JM Dan, C Havenar-Daughton, K Kendric, R Al-Kolla, K Kaushik, ... Science translational medicine 11 (478), eaau3776, 2019 | 136 | 2019 |
Cationic antimicrobial peptide resistance mechanisms of streptococcal pathogens CN LaRock, V Nizet Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (11), 3047-3054, 2015 | 122 | 2015 |
Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes DL LaRock, AF Johnson, S Wilde, JS Sands, MP Monteiro, CN LaRock Nature 605 (7910), 527-531, 2022 | 111 | 2022 |
Group A streptococcal M protein activates the NLRP3 inflammasome JA Valderrama, AM Riestra, NJ Gao, CN LaRock, N Gupta, SR Ali, ... Nature Microbiology 20, 40, 2017 | 93 | 2017 |
Burning down the house: cellular actions during pyroptosis CN LaRock, BT Cookson PLoS pathogens 9 (12), e1003793, 2013 | 84 | 2013 |
Integrin-like allosteric properties of the catch bond-forming FimH adhesin of Escherichia coli V Tchesnokova, P Aprikian, O Yakovenko, C LaRock, B Kidd, V Vogel, ... Journal of biological chemistry 283 (12), 7823-7833, 2008 | 84 | 2008 |
Modeling neuro-immune interactions during Zika virus infection P Mesci, A Macia, CN LaRock, L Tejwani, IR Fernandes, NA Suarez, ... Human Molecular Genetics 27 (1), 41-52, 2018 | 65 | 2018 |
A Metalloprotease Secreted by the Insect Pathogen Photorhabdus luminescens Induces Melanization KG Held, CN LaRock, DA D'Argenio, CA Berg, CM Collins Applied and Environmental Microbiology 73 (23), 7622-7628, 2007 | 59 | 2007 |
Group A streptococcal M1 protein sequesters cathelicidin to evade innate immune killing CN LaRock, S Döhrmann, J Todd, R Corriden, J Olson, T Johannssen, ... Cell host & microbe 18 (4), 471-477, 2015 | 56 | 2015 |
Antibiotic treatment, mechanisms for failure, and adjunctive therapies for infections by group A Streptococcus AF Johnson, CN LaRock Frontiers in Microbiology 12, 3163, 2021 | 54 | 2021 |
The Pseudomonas aeruginosa protease LasB directly activates IL-1β J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, ... EBioMedicine 60, 102984, 2020 | 52* | 2020 |
Inflammasome/IL-1β responses to streptococcal pathogens CN LaRock, V Nizet Frontiers in immunology 6, 518, 2015 | 52 | 2015 |
Transcriptome analysis of acyl-homoserine lactone-based quorum sensing regulation in Yersinia pestis CN LaRock, J Yu, AR Horswill, MR Parsek, FC Minion PLoS One 8 (4), e62337, 2013 | 36 | 2013 |
Group A streptococcal S protein utilizes red blood cells as immune camouflage and is a critical determinant for immune evasion IH Wierzbicki, A Campeau, D Dehaini, M Holay, X Wei, T Greene, M Ying, ... Cell reports 29 (10), 2979-2989. e15, 2019 | 34 | 2019 |
Group A streptococcus infection of the nasopharynx requires proinflammatory signaling through the interleukin-1 receptor DL LaRock, R Russell, AF Johnson, S Wilde, CN LaRock Infection and Immunity 88 (10), e00356-20, 2020 | 32 | 2020 |
3D bioprinted bacteriostatic hyperelastic bone scaffold for damage-specific bone regeneration M Shokouhimehr, AS Theus, A Kamalakar, L Ning, C Cao, ML Tomov, ... Polymers 13 (7), 1099, 2021 | 31 | 2021 |
Group A streptococcal M1 protein provides resistance against the antimicrobial activity of histones S Döhrmann, CN LaRock, EL Anderson, JN Cole, B Ryali, C Stewart, ... Scientific reports 7 (1), 43039, 2017 | 29 | 2017 |