Continuous‐flow technology—a tool for the safe manufacturing of active pharmaceutical ingredients B Gutmann, D Cantillo, CO Kappe Angewandte Chemie International Edition 54 (23), 6688-6728, 2015 | 1394 | 2015 |
Immobilized transition metals as catalysts for cross‐couplings in continuous flow—a critical assessment of the reaction mechanism and metal leaching D Cantillo, CO Kappe ChemCatChem 6 (12), 3286-3305, 2014 | 213 | 2014 |
In situ generated iron oxide nanocrystals as efficient and selective catalysts for the reduction of nitroarenes using a continuous flow method D Cantillo, M Baghbanzadeh, CO Kappe Angewandte Chemie International Edition 51 (40), 10190-10193, 2012 | 213 | 2012 |
Hydrazine-mediated reduction of nitro and azide functionalities catalyzed by highly active and reusable magnetic iron oxide nanocrystals D Cantillo, MM Moghaddam, CO Kappe The Journal of Organic Chemistry 78 (9), 4530-4542, 2013 | 180 | 2013 |
Continuous flow α-trifluoromethylation of ketones by metal-free visible light photoredox catalysis D Cantillo, O de Frutos, JA Rincon, C Mateos, CO Kappe Organic letters 16 (3), 896-899, 2014 | 166 | 2014 |
Kontinuierliche Durchflussverfahren: ein Werkzeug für die sichere Synthese von pharmazeutischen Wirkstoffen B Gutmann, D Cantillo, CO Kappe Angewandte Chemie 127 (23), 6788-6832, 2015 | 154 | 2015 |
Mechanistic insights on azide− nitrile cycloadditions: on the dialkyltin oxide− trimethylsilyl azide route and a new Vilsmeier− Haack-type organocatalyst D Cantillo, B Gutmann, CO Kappe Journal of the American Chemical Society 133 (12), 4465-4475, 2011 | 132 | 2011 |
Advanced real‐time process analytics for multistep synthesis in continuous flow P Sagmeister, R Lebl, I Castillo, J Rehrl, J Kruisz, M Sipek, M Horn, ... Angewandte Chemie International Edition 60 (15), 8139-8148, 2021 | 125 | 2021 |
Halogenation of organic compounds using continuous flow and microreactor technology D Cantillo, CO Kappe Reaction Chemistry & Engineering 2 (1), 7-19, 2017 | 123 | 2017 |
A scalable procedure for light-induced benzylic brominations in continuous flow D Cantillo, O de Frutos, JA Rincon, C Mateos, CO Kappe The Journal of Organic Chemistry 79 (1), 223-229, 2014 | 121 | 2014 |
A continuous-flow protocol for light-induced benzylic fluorinations D Cantillo, O de Frutos, JA Rincon, C Mateos, CO Kappe The Journal of Organic Chemistry 79 (17), 8486-8490, 2014 | 106 | 2014 |
A Unified Mechanistic View on the Morita− Baylis− Hillman Reaction: Computational and Experimental Investigations D Cantillo, CO Kappe The Journal of organic chemistry 75 (24), 8615-8626, 2010 | 104 | 2010 |
Translating batch electrochemistry to single-pass continuous flow conditions: an organic chemist’s guide S Maljuric, W Jud, CO Kappe, D Cantillo Journal of Flow Chemistry 10, 181-190, 2020 | 103 | 2020 |
In situ generation of diimide from hydrazine and oxygen: continuous-flow transfer hydrogenation of olefins. B Pieber, ST Martinez, D Cantillo, CO Kappe Angewandte Chemie 125 (39), 2013 | 99 | 2013 |
Benchmarking immobilized di-and triarylphosphine palladium catalysts for continuous-flow cross-coupling reactions: efficiency, durability, and metal leaching studies R Greco, W Goessler, D Cantillo, CO Kappe ACS Catalysis 5 (2), 1303-1312, 2015 | 84 | 2015 |
Assessing the whole range of CuAAC mechanisms by DFT calculations—on the intermediacy of copper acetylides D Cantillo, M Ávalos, R Babiano, P Cintas, JL Jiménez, JC Palacios Organic & Biomolecular Chemistry 9 (8), 2952-2958, 2011 | 76 | 2011 |
Catalyst‐free oxytrifluoromethylation of alkenes through paired electrolysis in organic‐aqueous media W Jud, CO Kappe, D Cantillo Chemistry–A European Journal 24 (65), 17234-17238, 2018 | 71 | 2018 |
Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols M Damm, C Nusshold, D Cantillo, GN Rechberger, K Gruber, W Sattler, ... Journal of proteomics 75 (18), 5533-5543, 2012 | 65 | 2012 |
Sequential nitration/hydrogenation protocol for the synthesis of triaminophloroglucinol: safe generation and use of an explosive intermediate under continuous-flow conditions D Cantillo, M Damm, D Dallinger, M Bauser, M Berger, CO Kappe Organic Process Research & Development 18 (11), 1360-1366, 2014 | 64 | 2014 |
Flash flow pyrolysis: mimicking flash vacuum pyrolysis in a high-temperature/high-pressure liquid-phase microreactor environment D Cantillo, H Sheibani, CO Kappe The Journal of Organic Chemistry 77 (5), 2463-2473, 2012 | 63 | 2012 |