Dramatically different phenotypes in mouse models of human Tay-Sachs and Sandhoff diseases D Phaneuf, N Wakamatsu, JQ Huang, A Borowski, AC Peterson, ... Human molecular genetics 5 (1), 1-14, 1996 | 260 | 1996 |
Cloning, expression and chromosomal mapping of human lysosomal sialidase and characterization of mutations in sialidosis AV Pshezhetsky, C Richard, L Michaud, S Igdoura, S Wang, MA Elsliger, ... Nature genetics 15 (3), 316-320, 1997 | 245 | 1997 |
Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and-competent breast tumor cells H Qin, Q Shao, SA Igdoura, MA Alaoui-Jamali, DW Laird Journal of Biological Chemistry 278 (32), 30005-30014, 2003 | 198 | 2003 |
Apoptotic cell death in mouse models of GM2 gangliosidosis and observations on human Tay-Sachs and Sandhoff diseases JQ Huang, JM Trasler, S Igdoura, J Michaud, N Hanai, RA Gravel Human molecular genetics 6 (11), 1879-1885, 1997 | 185 | 1997 |
The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice A Al-Jarallah, F Igdoura, Y Zhang, CB Tenedero, EJ White, ... Atherosclerosis 228 (1), 80-89, 2013 | 98 | 2013 |
Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice PF Lebeau, JH Byun, K Platko, AA Al-Hashimi, Š Lhoták, ME MacDonald, ... Jhep Reports 1 (6), 418-429, 2019 | 71 | 2019 |
The effects of diet on occlusive coronary artery atherosclerosis and myocardial infarction in scavenger receptor class B, type 1/low-density lipoprotein receptor double … M Fuller, O Dadoo, V Serkis, D Abutouk, M MacDonald, N Dhingani, ... Arteriosclerosis, thrombosis, and vascular biology 34 (11), 2394-2403, 2014 | 67 | 2014 |
Low density lipoprotein receptor-related protein-2 expression in efferent duct and epididymal epithelia: evidence in rats for its in vivo role in endocytosis of apolipoprotein … CR Morales, SA Igdoura, UA Wosu, J Boman, WS Argraves Biology of reproduction 55 (3), 676-683, 1996 | 67 | 1996 |
Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance PF Lebeau, JH Byun, K Platko, P Saliba, M Sguazzin, ME MacDonald, ... Nature communications 13 (1), 770, 2022 | 65 | 2022 |
Cloning of the cDNA and gene encoding mouse lysosomal sialidase and correction of sialidase deficiency in human sialidosis and mouse SM/J fibroblasts SA Igdoura, C Gafuik, C Mertineit, F Saberi, AV Pshezhetsky, M Potier, ... Human molecular genetics 7 (1), 115-120, 1998 | 64 | 1998 |
Differential expression of cathepsins B and D in testis and epididymis of adult rats. SA Igdoura, CR Morales, L Hermo Journal of Histochemistry & Cytochemistry 43 (5), 545-557, 1995 | 62 | 1995 |
Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice H Abo-Ouf, AWM Hooper, EJ White, HJ Janse van Rensburg, BL Trigatti, ... Human molecular genetics 22 (19), 3960-3975, 2013 | 61 | 2013 |
α-Mannosidases involved in N-glycan processing show cell specificity and distinct subcompartmentalization within the Golgi apparatus of cells in the testis and epididymis SA Igdoura, A Herscovics, A Lal, KW Moremen, CR Morales, L Hermo European journal of cell biology 78 (7), 441-452, 1999 | 54 | 1999 |
Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice EJ White, G Gyulay, Š Lhoták, MM Szewczyk, T Chong, MT Fuller, ... Journal of Biological Chemistry 293 (38), 14689-14706, 2018 | 51 | 2018 |
Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathwayss⃞ Y Zhang, AM Ahmed, N McFarlane, C Capone, DR Boreham, R Truant, ... Journal of lipid research 48 (2), 405-416, 2007 | 51 | 2007 |
Five novel mutations in the lysosomal sialidase gene (NEU1) in type II sialidosis patients and assessment of their impact on enzyme activity and intracellular … S Pattison, M Pankarican, CA Rupar, FL Graham, SA Igdoura Human mutation 23 (1), 32-39, 2004 | 50 | 2004 |
Role of sulfated glycoprotein‐1 (SGP‐1) in the disposal of residual bodies by Sertoli cells of the rat SA Igdoura, CR Morales Molecular reproduction and development 40 (1), 91-102, 1995 | 49 | 1995 |
Trafficking of sulfated glycoprotein-1 (prosaposin) to lysosomes or to the extracellular space in rat Sertoli cells SA Igdoura, A Rasky, CR Morales Cell and tissue research 283, 385-394, 1996 | 46 | 1996 |
Miglustat as a therapeutic agent: prospects and caveats RE Venier, SA Igdoura Journal of medical genetics 49 (9), 591-597, 2012 | 45 | 2012 |
Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine l-gulono-γ-lactone oxidase MN Ha, FL Graham, CK D'Souza, WJ Muller, SA Igdoura, HE Schellhorn Genomics 83 (3), 482-492, 2004 | 44 | 2004 |