Deciphering the structural basis of eukaryotic protein kinase regulation HS Meharena, P Chang, MM Keshwani, K Oruganty, AK Nene, N Kannan, ... PLoS biology 11 (10), e1001680, 2013 | 217 | 2013 |
The entropic force generated by intrinsically disordered segments tunes protein function ND Keul, K Oruganty, ETS Bergman, NR Beattie, WE McDonald, ... Nature 563 (7732), 584-588, 2018 | 133 | 2018 |
Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis JA Stefely, AG Reidenbach, A Ulbrich, K Oruganty, BJ Floyd, A Jochem, ... Molecular cell 57 (1), 83-94, 2015 | 130 | 2015 |
Relation extraction from clinical texts using domain invariant convolutional neural network NG Sunil Kumar Sahu, Ashish Anand, Krishnadev Oruganty Proceedings of the 15th Workshop on Biomedical Natural Language Processing …, 2016 | 129* | 2016 |
Interaction preferences across protein-protein interfaces of obligatory and non-obligatory components are different S De, O Krishnadev, N Srinivasan, N Rekha BMC structural biology 5 (1), 1-16, 2005 | 123 | 2005 |
The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner Fiona P Bailey, Dominic P Byrne, Krishnadev Oruganty, Claire E Eyers ... Biochem. J., 2015 | 92 | 2015 |
Prediction of protein–protein interactions between human host and a pathogen and its application to three pathogenic bacteria O Krishnadev, N Srinivasan International journal of biological macromolecules 48 (4), 613-619, 2011 | 62 | 2011 |
Identification of a hidden strain switch provides clues to an ancient structural mechanism in protein kinases K Oruganty, NS Talathi, ZA Wood, N Kannan Proceedings of the National Academy of Sciences 110 (3), 924-929, 2013 | 48 | 2013 |
Design principles underpinning the regulatory diversity of protein kinases K Oruganty, N Kannan Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012 | 43 | 2012 |
Inhibiting EGFR dimerization using triazolyl-bridged dimerization arm mimics LE Hanold, K Oruganty, NT Ton, AM Beedle, N Kannan, EJ Kennedy PLoS One 10 (3), e0118796, 2015 | 41 | 2015 |
A data integration approach to predict host-pathogen protein-protein interactions: application to recognize protein interactions between human and a malarial parasite O Krishnadev, N Srinivasan In silico biology 8 (3-4), 235-250, 2008 | 40 | 2008 |
Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization SM Krishnadev Oruganty, annie Kwon, Dominic P. Byrne, Samantha Ferries ... PLoS Genetics 12 (2), e1005885, 2016 | 39 | 2016 |
Prediction of protein–protein interactions between Helicobacter pylori and a human host N Tyagi, O Krishnadev, N Srinivasan Molecular bioSystems 5 (12), 1630-1635, 2009 | 36 | 2009 |
MulPSSM: a database of multiple position-specific scoring matrices of protein domain families VS Gowri, O Krishnadev, CS Swamy, N Srinivasan Nucleic acids research 34 (suppl_1), D243-D246, 2006 | 35 | 2006 |
A graph spectral analysis of the structural similarity network of protein chains O Krishnadev, KV Brinda, S Vishveshwara PROTEINS: Structure, Function, and Bioinformatics 61 (1), 152-163, 2005 | 23 | 2005 |
Co-Conserved MAPK Features Couple D-Domain Docking Groove to Distal Allosteric Sites via the C-Terminal Flanking Tail KN Nguyen T, Ruan Z, Oruganty K PLoS One. 10 (3), e0119636, 2015 | 22 | 2015 |
Identification and classification of small molecule kinases: insights into substrate recognition and specificity K Oruganty, EE Talevich, AF Neuwald, N Kannan BMC evolutionary biology 16 (1), 1-14, 2016 | 21 | 2016 |
Strategies for the effective identification of remotely related sequences in multiple PSSM search approach VS Gowri, KG Tina, O Krishnadev, N Srinivasan Proteins: Structure, Function, and Bioinformatics 67 (4), 789-794, 2007 | 18 | 2007 |
AlignHUSH: alignment of HMMs using structure and hydrophobicity information O Krishnadev, N Srinivasan BMC bioinformatics 12 (1), 1-13, 2011 | 14 | 2011 |
PRODOC: a resource for the comparison of tethered protein domain architectures with in-built information on remotely related domain families O Krishnadev, N Rekha, SB Pandit, S Abhiman, S Mohanty, LS Swapna, ... Nucleic acids research 33 (suppl_2), W126-W129, 2005 | 14 | 2005 |