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Lei Guo
Lei Guo
在 utsouthwestern.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease
JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, ...
Nature 586 (7831), 735-740, 2020
3042020
Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2
X Zhou, S Wahane, MS Friedl, M Kluge, CC Friedel, K Avrampou, ...
Nature neuroscience 23 (3), 337-350, 2020
2162020
Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets
RA Neff, M Wang, S Vatansever, L Guo, C Ming, Q Wang, E Wang, ...
Science advances 7 (2), eabb5398, 2021
2102021
Transformative network modeling of multi-omics data reveals detailed circuits, key regulators, and potential therapeutics for Alzheimer’s disease
M Wang, A Li, M Sekiya, ND Beckmann, X Quan, N Schrode, ...
Neuron 109 (2), 257-272. e14, 2021
1352021
Sex differences in Alzheimer’s disease: insights from the multiomics landscape
L Guo, MB Zhong, L Zhang, B Zhang, D Cai
Biological psychiatry 91 (1), 61-71, 2022
1182022
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
DD Shi, MR Savani, MM Levitt, AC Wang, JE Endress, CE Bird, J Buehler, ...
Cancer cell 40 (9), 939-956. e16, 2022
772022
MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer’s disease pathogenesis
J Cao, M Huang, L Guo, L Zhu, J Hou, L Zhang, A Pero, S Ng, ...
Molecular psychiatry 26 (9), 4687-4701, 2021
582021
Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity
S Wahane, X Zhou, X Zhou, L Guo, MS Friedl, M Kluge, A Ramakrishnan, ...
Science Advances 7 (9), eabd8811, 2021
482021
Sex specific molecular networks and key drivers of Alzheimer’s disease
L Guo, J Cao, J Hou, Y Li, M Huang, L Zhu, L Zhang, Y Lee, ML Duarte, ...
Molecular neurodegeneration 18 (1), 39, 2023
282023
Dissecting embryonic and extra-embryonic lineage crosstalk with stem cell co-culture
Y Wei, E Zhang, L Yu, B Ci, L Guo, M Sakurai, S Takii, J Liu, D Schmitz, ...
Cell 186 (26), 5859-5875.e24, 2023
212023
Distinct functional properties of murine perinatal and adult adipose progenitor subpopulations
Q Zhang, B Shan, L Guo, M Shao, L Vishvanath, G Elmquist, L Xu, ...
Nature metabolism 4 (8), 1055-1070, 2022
132022
Itaconate-producing neutrophils regulate local and systemic inflammation following trauma
JL Crossley, S Ostashevskaya-Gohstand, S Comazzetto, JS Hook, L Guo, ...
JCI insight 8 (20), 2023
122023
Genome‐wide methylomic regulation of multiscale gene networks in Alzheimer's disease
E Wang, M Wang, L Guo, JF Fullard, C Micallef, J Bendl, W Song, C Ming, ...
Alzheimer's & Dementia 19 (8), 3472-3495, 2023
112023
Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets. Sci Adv 7: eabb5398
RA Neff, M Wang, S Vatansever, L Guo, C Ming, Q Wang, E Wang, ...
112021
Numb is required for optimal contraction of skeletal muscle
R De Gasperi, C Mo, D Azulai, Z Wang, LM Harlow, Y Du, Z Graham, ...
Journal of Cachexia, Sarcopenia and Muscle 13 (1), 454-466, 2022
102022
PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer
CC Lin, TC Chang, Y Wang, L Guo, Y Gao, E Bikorimana, A Lemoff, ...
Nature communications 15 (1), 2287, 2024
92024
Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence
L Xu, JL Pierce, A Sanchez, KS Chen, AA Shukla, NJ Fustino, SH Stuart, ...
Nature communications 14 (1), 2636, 2023
82023
TWIST2-mediated chromatin remodeling promotes fusion-negative rhabdomyosarcoma
AM Shah, L Guo, MG Morales, P Jaichander, K Chen, H Huang, ...
Science Advances 9 (17), eade8184, 2023
72023
Cross-talk between histone methyltransferases and demethylases regulate REST transcription during neurogenesis
J Swaminathan, S Maegawa, S Shaik, A Sharma, J Bravo-Alegria, L Guo, ...
Frontiers in Oncology 12, 855167, 2022
62022
The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair
H Kang, AL Strong, Y Sun, L Guo, C Juan, AC Bancroft, JH Choi, ...
Bone Research 12 (1), 17, 2024
52024
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