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Jianming Zhang
Jianming Zhang
Shanghai Jiaotong University, Zhangjiang Institute for Advanced Study,Institute of Translational Med
在 sjtu.edu.cn 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Targeting cancer with small molecule kinase inhibitors
J Zhang, PL Yang, NS Gray
Nature reviews cancer 9 (1), 28-39, 2009
33112009
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
CC Thoreen, SA Kang, JW Chang, Q Liu, J Zhang, Y Gao, LJ Reichling, ...
Journal of Biological Chemistry 284 (12), 8023-8032, 2009
20422009
Activating mutations in ALK provide a therapeutic target in neuroblastoma
RE George, T Sanda, M Hanna, S Fröhling, WL Ii, J Zhang, Y Ahn, ...
Nature 455 (7215), 975-978, 2008
10182008
Systematic identification of culture conditions for induction and maintenance of naive human pluripotency
TW Theunissen, BE Powell, H Wang, M Mitalipova, DA Faddah, J Reddy, ...
Cell stem cell 15 (4), 471-487, 2014
9622014
MEK1 mutations confer resistance to MEK and B-RAF inhibition
CM Emery, KG Vijayendran, MC Zipser, AM Sawyer, L Niu, JJ Kim, ...
Proceedings of the National Academy of Sciences 106 (48), 20411-20416, 2009
7702009
Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors
J Zhang, FJ Adrián, W Jahnke, SW Cowan-Jacob, AG Li, RE Iacob, T Sim, ...
Nature 463 (7280), 501-506, 2010
6912010
Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer
PS Hammerman, ML Sos, AH Ramos, C Xu, A Dutt, W Zhou, LE Brace, ...
Cancer discovery 1 (1), 78-89, 2011
5832011
Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor
CL Christensen, N Kwiatkowski, BJ Abraham, J Carretero, F Al-Shahrour, ...
Cancer cell 26 (6), 909-922, 2014
4532014
Discovery of potent and selective covalent inhibitors of JNK
T Zhang, F Inesta-Vaquera, M Niepel, J Zhang, SB Ficarro, T Machleidt, ...
Chemistry & biology 19 (1), 140-154, 2012
3612012
In situ kinase profiling reveals functionally relevant properties of native kinases
MP Patricelli, TK Nomanbhoy, J Wu, H Brown, D Zhou, J Zhang, ...
Chemistry & biology 18 (6), 699-710, 2011
3482011
Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective …
Q Liu, JW Chang, J Wang, SA Kang, CC Thoreen, A Markhard, W Hur, ...
Journal of medicinal chemistry 53 (19), 7146-7155, 2010
2812010
A structure-guided approach to creating covalent FGFR inhibitors
W Zhou, W Hur, U McDermott, A Dutt, W Xian, SB Ficarro, J Zhang, ...
Chemistry & biology 17 (3), 285-295, 2010
2152010
Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in LKB1-Mutant Lung Cancer
Y Liu, K Marks, GS Cowley, J Carretero, Q Liu, TJF Nieland, C Xu, ...
Cancer discovery 3 (8), 870-879, 2013
1432013
Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells
M Taipale, I Krykbaeva, L Whitesell, S Santagata, J Zhang, Q Liu, NS Gray, ...
Nature biotechnology 31 (7), 630-637, 2013
1402013
EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma
B Miao, Z Ji, L Tan, M Taylor, J Zhang, HG Choi, DT Frederick, R Kumar, ...
Cancer discovery 5 (3), 274-287, 2015
1382015
A complex network of factors with overlapping affinities represses splicing through intronic elements
Y Wang, X Xiao, J Zhang, R Choudhury, A Robertson, K Li, M Ma, ...
Nature structural & molecular biology 20 (1), 36-45, 2013
1302013
Evolving protein functional diversity in new genes of Drosophila
J Zhang, AM Dean, F Brunet, M Long
Proceedings of the National Academy of Sciences 101 (46), 16246-16250, 2004
1212004
Direct targeting of β-catenin by a small molecule stimulates proteasomal degradation and suppresses oncogenic Wnt/β-catenin signaling
SY Hwang, X Deng, S Byun, C Lee, SJ Lee, H Suh, J Zhang, Q Kang, ...
Cell reports 16 (1), 28-36, 2016
1192016
The Origin of the Jingwei Gene and the Complex Modular Structure of Its Parental Gene, Yellow Emperor, in Drosophila melanogaster
W Wang, J Zhang, C Alvarez, A Llopart, M Long
Molecular Biology and Evolution 17 (9), 1294-1301, 2000
1182000
Targeting Cdk11 in osteosarcoma cells using the CRISPR‐cas9 system
Y Feng, S Sassi, JK Shen, X Yang, Y Gao, E Osaka, J Zhang, S Yang, ...
Journal of orthopaedic research 33 (2), 199-207, 2015
932015
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