Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts G Guaitoli, F Raimondi, BK Gilsbach, Y Gómez-Llorente, E Deyaert, ... Proceedings of the National Academy of Sciences 113 (30), E4357-E4366, 2016 | 161 | 2016 |
Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain G Piccoli, F Onofri, MD Cirnaru, CJO Kaiser, P Jagtap, A Kastenmüller, ... Molecular and cellular biology 34 (12), 2147-2161, 2014 | 121 | 2014 |
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1 I Wang, J Hennig, PKA Jagtap, M Sonntag, J Valcárcel, M Sattler Nucleic acids research 42 (9), 5949-5966, 2014 | 90 | 2014 |
Segmental, Domain‐Selective Perdeuteration and Small‐Angle Neutron Scattering for Structural Analysis of Multi‐Domain Proteins M Sonntag, PKA Jagtap, B Simon, MS Appavou, A Geerlof, R Stehle, ... Angewandte Chemie 129 (32), 9450-9453, 2017 | 57 | 2017 |
Crystal structures identify an atypical two-metal-ion mechanism for uridyltransfer in GlmU: its significance to sugar nucleotidyl transferases PKA Jagtap, SK Verma, N Vithani, VS Bais, B Prakash Journal of molecular biology 425 (10), 1745-1759, 2013 | 35 | 2013 |
Integrative Structural Biology of Protein-RNA Complexes L Dimitrova-Paternoga, PKA Jagtap, PC Chen, J Hennig Structure 28 (1), 6-28, 2020 | 34 | 2020 |
Substrate-bound crystal structures reveal features unique to Mycobacterium tuberculosis N-acetyl-glucosamine 1-phosphate uridyltransferase and a catalytic mechanism for acetyl … PKA Jagtap, V Soni, N Vithani, GD Jhingan, VS Bais, VK Nandicoori, ... Journal of Biological Chemistry 287 (47), 39524-39537, 2012 | 33 | 2012 |
Selective inhibitors of FKBP51 employ conformational selection of dynamic invisible states PKA Jagtap, S Asami, C Sippel, VRI Kaila, F Hausch, M Sattler Angewandte Chemie 131 (28), 9529-9533, 2019 | 30 | 2019 |
Structural basis for EarP-mediated arginine glycosylation of translation elongation factor EF-P R Krafczyk, J Macošek, PKA Jagtap, D Gast, S Wunder, P Mitra, AK Jha, ... MBio 8 (5), 10.1128/mbio. 01412-17, 2017 | 28 | 2017 |
Molecular basis of mRNA transport by a kinesin-1–atypical tropomyosin complex L Dimitrova-Paternoga, PKA Jagtap, A Cyrklaff, K Lapouge, P Sehr, ... Genes & development 35 (13-14), 976-991, 2021 | 26 | 2021 |
Switching the post-translational modification of translation elongation factor EF P W Volkwein, R Krafczyk, PKA Jagtap, M Parr, E Mankina, J Macošek, ... Frontiers in Microbiology 10, 1148, 2019 | 26 | 2019 |
Rational design of cyclic peptide inhibitors of U2AF Homology Motif (UHM) domains to modulate Pre-mRNA splicing PKA Jagtap, D Garg, TG Kapp, CL Will, O Demmer, R Lührmann, ... Journal of medicinal chemistry 59 (22), 10190-10197, 2016 | 26 | 2016 |
Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly PKA Jagtap, T Kubelka, K Soni, CL Will, D Garg, C Sippel, TG Kapp, ... Nature Communications 11 (1), 5621, 2020 | 25 | 2020 |
Pseudo-RNA-binding domains mediate RNA structure specificity in upstream of N-Ras NM Hollmann, PKA Jagtap, P Masiewicz, T Guitart, B Simon, J Provaznik, ... Cell Reports 32 (3), 2020 | 22 | 2020 |
Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless PK Ankush Jagtap, M Müller, P Masiewicz, S von Bülow, NM Hollmann, ... Nucleic acids research 47 (8), 4319-4333, 2019 | 17 | 2019 |
Transcriptional regulation of the Nε‐fructoselysine metabolism in Escherichia coli by global and substrate‐specific cues B Graf von Armansperg, F Koller, N Gericke, M Hellwig, PKA Jagtap, ... Molecular Microbiology, 2020 | 15 | 2020 |
Divergent evolution toward sex chromosome-specific gene regulation in Drosophila R Villa, PKA Jagtap, AW Thomae, AC Sparr, I Forné, J Hennig, T Straub, ... Genes & development 35 (13-14), 1055-1070, 2021 | 13 | 2021 |
Mechanism of Mg2+-Accompanied Product Release in Sugar Nucleotidyltransferases N Vithani, PKA Jagtap, SK Verma, R Tripathi, S Awasthi, NN Nair, ... Structure 26 (3), 459-466. e3, 2018 | 13 | 2018 |
A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion L Zhang, S Lovell, E De Vita, PKA Jagtap, D Lucy, A Goya Grocin, S Kjær, ... Journal of the American Chemical Society 144 (49), 22493-22504, 2022 | 8 | 2022 |
Structural basis for specific RNA recognition by the alternative splicing factor RBM5 K Soni, PKA Jagtap, S Martínez-Lumbreras, S Bonnal, A Geerlof, R Stehle, ... Nature Communications 14 (1), 4233, 2023 | 7 | 2023 |