Endocrine disrupting chemicals targeting estrogen receptor signaling: identification and mechanisms of action EK Shanle, W Xu Chemical research in toxicology 24 (1), 6-19, 2011 | 625 | 2011 |
Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome YA Lam, W Xu, GN DeMartino, RE Cohen Nature 385 (6618), 737-740, 1997 | 605 | 1997 |
A transcriptional switch mediated by cofactor methylation W Xu, H Chen, K Du, H Asahara, M Tini, BM Emerson, M Montminy, ... Science 294 (5551), 2507-2511, 2001 | 512 | 2001 |
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators SJ Demarest, M Martinez-Yamout, J Chung, H Chen, W Xu, HJ Dyson, ... Nature 415 (6871), 549-553, 2002 | 505 | 2002 |
Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1 T Yao, L Song, W Xu, GN DeMartino, L Florens, SK Swanson, ... Nature cell biology 8 (9), 994-1002, 2006 | 402 | 2006 |
CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis L Wang, Z Zhao, MB Meyer, S Saha, M Yu, A Guo, KB Wisinski, W Huang, ... Cancer cell 25 (1), 21-36, 2014 | 318 | 2014 |
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy Y Gao, NT Nihira, X Bu, C Chu, J Zhang, A Kolodziejczyk, Y Fan, NT Chan, ... Nature cell biology 22 (9), 1064-1075, 2020 | 273 | 2020 |
PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis F Liu, F Ma, Y Wang, L Hao, H Zeng, C Jia, Y Wang, P Liu, IM Ong, B Li, ... Nature cell biology 19 (11), 1358-1370, 2017 | 255 | 2017 |
TDRD3 is an effector molecule for arginine-methylated histone marks Y Yang, Y Lu, A Espejo, J Wu, W Xu, S Liang, MT Bedford Molecular cell 40 (6), 1016-1023, 2010 | 255 | 2010 |
Androgen receptor splice variants dimerize to transactivate target genes D Xu, Y Zhan, Y Qi, B Cao, S Bai, W Xu, SS Gambhir, P Lee, O Sartor, ... Cancer research 75 (17), 3663-3671, 2015 | 221 | 2015 |
Androgen-induced recruitment of RNA polymerase II to a nuclear receptor–p160 coactivator complex MC Louie, HQ Yang, AH Ma, W Xu, JX Zou, HJ Kung, HW Chen Proceedings of the National Academy of Sciences 100 (5), 2226-2230, 2003 | 198 | 2003 |
Selectively targeting estrogen receptors for cancer treatment EK Shanle, W Xu Advanced drug delivery reviews 62 (13), 1265-1276, 2010 | 167 | 2010 |
Intermolecular interactions identify ligand-selective activity of estrogen receptor α/β dimers E Powell, W Xu Proceedings of the National Academy of Sciences 105 (48), 19012-19017, 2008 | 134 | 2008 |
Phosphorylation-mediated inactivation of coactivator-associated arginine methyltransferase 1 K Higashimoto, P Kuhn, D Desai, X Cheng, W Xu Proceedings of the National Academy of Sciences 104 (30), 12318-12323, 2007 | 132 | 2007 |
Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition E Shishkova, H Zeng, F Liu, NW Kwiecien, AS Hebert, JJ Coon, W Xu Nature communications 8 (1), 15571, 2017 | 130 | 2017 |
Tamoxifen enhances stemness and promotes metastasis of ERα36+ breast cancer by upregulating ALDH1A1 in cancer cells Q Wang, J Jiang, G Ying, XQ Xie, X Zhang, W Xu, X Zhang, E Song, H Bu, ... Cell research 28 (3), 336-358, 2018 | 129 | 2018 |
SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis RR Nofsinger, P Li, SH Hong, JW Jonker, GD Barish, H Ying, S Cheng, ... Proceedings of the National Academy of Sciences 105 (50), 20021-20026, 2008 | 115 | 2008 |
CARM1 is an important determinant of ERα-dependent breast cancer cell differentiation and proliferation in breast cancer cells M Al-Dhaheri, J Wu, GP Skliris, J Li, K Higashimato, Y Wang, KP White, ... Cancer research 71 (6), 2118-2128, 2011 | 108 | 2011 |
Quantum-dot-based theranostic micelles conjugated with an anti-EGFR nanobody for triple-negative breast cancer therapy Y Wang, Y Wang, G Chen, Y Li, W Xu, S Gong ACS applied materials & interfaces 9 (36), 30297-30305, 2017 | 103 | 2017 |
Aminoflavone-loaded EGFR-targeted unimolecular micelle nanoparticles exhibit anti-cancer effects in triple negative breast cancer AM Brinkman, G Chen, Y Wang, CJ Hedman, NM Sherer, TC Havighurst, ... Biomaterials 101, 20-31, 2016 | 101 | 2016 |