| The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells J Wenzel, J Lampe, H Müller-Fielitz, R Schuster, M Zille, K Müller, ... Nature neuroscience 24 (11), 1522-1533, 2021 | 228 | 2021 |
| Intracellular transport and regulation of transcytosis across the blood–brain barrier R Villaseñor, J Lampe, M Schwaninger, L Collin Cellular and molecular life sciences 76, 1081-1092, 2019 | 191 | 2019 |
| Signal processing by the endosomal system R Villaseñor, Y Kalaidzidis, M Zerial Current opinion in cell biology 39, 53-60, 2016 | 174 | 2016 |
| Cellular uptake mechanisms and endosomal trafficking of supercharged proteins DB Thompson, R Villaseñor, BM Dorr, M Zerial, DR Liu Chemistry & biology 19 (7), 831-843, 2012 | 165 | 2012 |
| Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes R Villasenor, H Nonaka, P Del Conte-Zerial, Y Kalaidzidis, M Zerial Elife 4, e06156, 2015 | 127 | 2015 |
| The mitogen-activated protein kinase p38 is involved in insect defense against Cry toxins from Bacillus thuringiensis A Cancino-Rodezno, C Alexander, R Villaseñor, S Pacheco, H Porta, ... Insect biochemistry and molecular biology 40 (1), 58-63, 2010 | 118 | 2010 |
| Region-specific permeability of the blood–brain barrier upon pericyte loss R Villasenor, B Kuennecke, L Ozmen, M Ammann, C Kugler, F Grüninger, ... Journal of Cerebral Blood Flow & Metabolism 37 (12), 3683-3694, 2017 | 111 | 2017 |
| Sorting tubules regulate blood-brain barrier transcytosis R Villaseñor, M Schilling, J Sundaresan, Y Lutz, L Collin Cell reports 21 (11), 3256-3270, 2017 | 95 | 2017 |
| Trafficking of endogenous immunoglobulins by endothelial cells at the blood-brain barrier R Villaseñor, L Ozmen, N Messaddeq, F Grüninger, H Loetscher, A Keller, ... Scientific reports 6 (1), 25658, 2016 | 85 | 2016 |
| A general theoretical framework to infer endosomal network dynamics from quantitative image analysis L Foret, JE Dawson, R Villasenor, C Collinet, A Deutsch, L Brusch, ... Current Biology 22 (15), 1381-1390, 2012 | 85 | 2012 |
| Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V C Schmees, R Villasenor, W Zheng, H Ma, M Zerial, CH Heldin, ... Molecular biology of the cell 23 (13), 2571-2582, 2012 | 55 | 2012 |
| Are biotransformation studies of therapeutic proteins needed? Scientific considerations and technical challenges S Schadt, S Hauri, F Lopes, MR Edelmann, RF Staack, R Villaseñor, ... Drug Metabolism and Disposition 47 (12), 1443-1456, 2019 | 36 | 2019 |
| Investigating receptor-mediated antibody transcytosis using blood–brain barrier organoid arrays C Simonneau, M Duschmalé, A Gavrilov, N Brandenberg, S Hoehnel, ... Fluids and Barriers of the CNS 18, 1-17, 2021 | 35 | 2021 |
| Inhibition of EGF uptake by nephrotoxic antisense drugs in vitro and implications for preclinical safety profiling A Moisan, M Gubler, JD Zhang, Y Tessier, KD Erichsen, S Sewing, ... Molecular Therapy-Nucleic Acids 6, 89-105, 2017 | 35 | 2017 |
| Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct A Gehrlein, V Udayar, N Anastasi, ML Morella, I Ruf, D Brugger, ... Nature communications 14 (1), 2057, 2023 | 21 | 2023 |
| Microphysiological neurovascular barriers to model the inner retinal microvasculature TL Maurissen, G Pavlou, C Bichsel, R Villaseñor, RD Kamm, H Ragelle Journal of Personalized Medicine 12 (2), 148, 2022 | 11 | 2022 |
| High-resolution confocal imaging of the blood-brain barrier: imaging, 3D reconstruction, and quantification of transcytosis R Villaseñor, L Collin Journal of Visualized Experiments: Jove, 56407, 2017 | 9 | 2017 |
| High throughput blood-brain barrier organoid generation and assessment of receptor-mediated antibody transcytosis E Kassianidou, C Simonneau, A Gavrilov, R Villaseñor Bio-protocol 12 (8), e4399-e4399, 2022 | 5 | 2022 |
| Learning microscopic kinetic characteristic of endosomal network by quantitative analysis of snap-shot microscopy images Y Kalaidzidis, L Foret, JE Dawson, R Villaseñor, F Jülicher, M Zerial Proceedings of the International Conference on Bioinformatics …, 2013 | 2 | 2013 |
| Advanced Tissue Technologies of Blood-Brain Barrier Organoids as High Throughput Toxicity Readouts in Drug Development L Bell, C Simonneau, C Zanini, E Kassianidou, C Zundel, R Neff, ... bioRxiv, 2024.09. 09.611987, 2024 | | 2024 |
