| Nutlin-3a is a potential therapeutic for ewing sarcoma KI Pishas, F Al-Ejeh, I Zinonos, R Kumar, A Evdokiou, MP Brown, ... Clinical Cancer Research 17 (3), 494-504, 2011 | 83 | 2011 |
| Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting ER Theisen, KI Pishas, RS Saund, SL Lessnick Oncotarget 7 (14), 17616, 2016 | 75 | 2016 |
| Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma with SP-2509 engages the endoplasmic reticulum stress response KI Pishas, CD Drenberg, C Taslim, ER Theisen, KM Johnson, RS Saund, ... Molecular cancer therapeutics 17 (9), 1902-1916, 2018 | 66 | 2018 |
| Recent advances in targeted therapy for Ewing sarcoma KI Pishas, SL Lessnick F1000Research 5, 2016 | 60 | 2016 |
| Targeting the p53 pathway in Ewing sarcoma PM Neilsen, KI Pishas, DF Callen, DM Thomas Sarcoma 2011 (1), 746939, 2011 | 45 | 2011 |
| Mutant p53 upregulates alpha-1 antitrypsin expression and promotes invasion in lung cancer R Shakya, GA Tarulli, L Sheng, NA Lokman, C Ricciardelli, KI Pishas, ... Oncogene 36 (31), 4469-4480, 2017 | 41 | 2017 |
| Identification of vitamin D3 target genes in human breast cancer tissue L Sheng, PH Anderson, AG Turner, KI Pishas, DJ Dhatrak, PG Gill, ... The Journal of steroid biochemistry and molecular biology 164, 90-97, 2016 | 38 | 2016 |
| XI-006 induces potent p53-independent apoptosis in Ewing sarcoma KI Pishas, A Adwal, SJ Neuhaus, MT Clayer, G Farshid, AH Staudacher, ... Scientific reports 5 (1), 11465, 2015 | 31 | 2015 |
| Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling KI Pishas, SJ Neuhaus, MT Clayer, AW Schreiber, DM Lawrence, ... Cancer research 74 (3), 921-931, 2014 | 28 | 2014 |
| Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein ER Theisen, J Selich-Anderson, KR Miller, JM Tanner, C Taslim, ... Epigenetics 16 (4), 405-424, 2021 | 25 | 2021 |
| Multiomic analysis of homologous recombination-deficient end-stage high-grade serous ovarian cancer NL Burdett, MO Willis, K Alsop, AL Hunt, A Pandey, PT Hamilton, T Abulez, ... Nature genetics 55 (3), 437-450, 2023 | 23 | 2023 |
| New 26S proteasome inhibitors with high selectivity for chymotrypsin-like activity and p53-dependent cytotoxicity PM Neilsen, AD Pehere, KI Pishas, DF Callen, AD Abell ACS Chemical Biology 8 (2), 353-359, 2013 | 23 | 2013 |
| A comparison of vitamin D activity in paired non-malignant and malignant human breast tissues RJ Suetani, K Ho, S Jindal, J Manavis, PM Neilsen, KI Pishas, E Rippy, ... Molecular and cellular endocrinology 362 (1-2), 202-210, 2012 | 21 | 2012 |
| Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis ER Theisen, KR Miller, IA Showpnil, C Taslim, KI Pishas, SL Lessnick Genes & cancer 10 (1-2), 21, 2019 | 19 | 2019 |
| Molecular characterization of low-grade serous ovarian carcinoma identifies genomic aberrations according to hormone receptor expression D Cheasley, ML Fernandez, M Köbel, H Kim, A Dawson, J Hoenisch, ... NPJ precision oncology 6 (1), 47, 2022 | 16 | 2022 |
| Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation KI Pishas, SL Lessnick Oncotarget 9 (92), 36413, 2018 | 15 | 2018 |
| Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma DT Weaver, KI Pishas, D Williamson, J Scarborough, SL Lessnick, ... PLoS Computational Biology 17 (10), e1008755, 2021 | 10 | 2021 |
| Mitochondrial dysfunction is a driver of SP-2509 drug resistance in Ewing sarcoma EJ Tokarsky, JC Crow, LM Guenther, J Sherman, C Taslim, G Alexe, ... Molecular Cancer Research 20 (7), 1035-1046, 2022 | 7 | 2022 |
| Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma PO Patel, KI Pishas, C Taslim, J Selich-Anderson, ER Theisen, ... Oncotarget 10 (39), 3865, 2019 | 7 | 2019 |
| Pre-activation of the p53 pathway through Nutlin-3a sensitises sarcomas to drozitumab therapy KI Pishas, SJ Neuhaus, MT Clayer, A Adwal, MP Brown, A Evdokiou, ... Oncology Reports 30 (1), 471-477, 2013 | 3 | 2013 |
