The symbiotic relationship between drug discovery and organic chemistry OO Grygorenko, DM Volochnyuk, SV Ryabukhin, DB Judd Chemistry–A European Journal 26 (6), 1196-1237, 2020 | 137 | 2020 |
Recyclizations of 3-formylchromones with binucleophiles AS Plaskon, OO Grygorenko, SV Ryabukhin Tetrahedron 68 (13), 2743-2757, 2012 | 118 | 2012 |
Combinatorial knoevenagel reactions SV Ryabukhin, AS Plaskon, DM Volochnyuk, SE Pipko, AN Shivanyuk, ... Journal of Combinatorial Chemistry 9 (6), 1073-1078, 2007 | 109 | 2007 |
N-Substituted ureas and thioureas in Biginelli reaction promoted by chlorotrimethylsilane: Convenient synthesis of N1-alkyl-, N1-aryl-, and N1, N3-dialkyl-3, 4-dihydropyrimidin … SV Ryabukhin, AS Plaskon, EN Ostapchuk, DM Volochnyuk, ... Synthesis 2007 (03), 417-427, 2007 | 106 | 2007 |
Synthesis of fused imidazoles and benzothiazoles from (hetero) aromatic ortho-diamines or ortho-aminothiophenol and aldehydes promoted by chlorotrimethylsilane SV Ryabukhin, AS Plaskon, DM Volochnyuk, AA Tolmachev Synthesis 2006 (21), 3715-3726, 2006 | 98 | 2006 |
Enamine real database: Making chemical diversity real AN Shivanyuk, SV Ryabukhin, A Tolmachev, AV Bogolyubsky, ... Chemistry today 25 (6), 58-59, 2007 | 84 | 2007 |
Evolution of commercially available compounds for HTS DM Volochnyuk, SV Ryabukhin, YS Moroz, O Savych, A Chuprina, ... Drug Discovery Today 24 (2), 390-402, 2019 | 70 | 2019 |
Synthesis of quinolines from 3-formylchromone AS Plaskon, SV Ryabukhin, DM Volochnyuk, KS Gavrilenko, ... The Journal of Organic Chemistry 73 (15), 6010-6013, 2008 | 59 | 2008 |
Aminoheterocycles as synthons for combinatorial Biginelli reactions SV Ryabukhin, AS Plaskon, SY Boron, DM Volochnyuk, AA Tolmachev Molecular diversity 15, 189-195, 2011 | 56 | 2011 |
Effect of gem‐Difluorination on the Key Physicochemical Properties Relevant to Medicinal Chemistry: The Case of Functionalized Cycloalkanes S Holovach, KP Melnykov, A Skreminskiy, M Herasymchuk, O Tavlui, ... Chemistry–A European Journal 28 (19), e202200331, 2022 | 52 | 2022 |
3-haloquinolines by friedlander reaction of α-haloketones SV Ryabukhin, VS Naumchik, AS Plaskon, OO Grygorenko, ... The Journal of Organic Chemistry 76 (14), 5774-5781, 2011 | 52 | 2011 |
CF3-substituted 1, 3-dicarbonyl compounds in the Biginelli reaction promoted by chlorotrimethylsilane SV Ryabukhin, AS Plaskon, EN Ostapchuk, DM Volochnyuk, OV Shishkin, ... Journal of Fluorine Chemistry 129 (7), 625-631, 2008 | 52 | 2008 |
A close-up look at the chemical space of commercially available building blocks for medicinal chemistry Y Zabolotna, DM Volochnyuk, SV Ryabukhin, D Horvath, KS Gavrilenko, ... Journal of chemical information and modeling 62 (9), 2171-2185, 2021 | 48 | 2021 |
Chlorotrimethylsilane-mediated Friedländer Synthesis of polysubstituted quinolines SV Ryabukhin, DM Volochnyuk, AS Plaskon, VS Naumchik, ... Synthesis 2007 (08), 1214-1224, 2007 | 47 | 2007 |
Approach to the library of fused pyridine-4-carboxylic acids by Combes-type reaction of acyl pyruvates and electron-rich amino heterocycles DM Volochnyuk, SV Ryabukhin, AS Plaskon, YV Dmytriv, OO Grygorenko, ... Journal of Combinatorial Chemistry 12 (4), 510-517, 2010 | 46 | 2010 |
3-Formylchromones in Guareschi synthesis of 5-(2-hydroxybenzoyl)-2-pyridones SV Ryabukhin, AS Plaskon, DM Volochnyuk, AA Tolmachev Synlett 2004 (13), 2287-2290, 2004 | 46 | 2004 |
Acyl pyruvates as synthons in the Biginelli reaction SV Ryabukhin, AS Plaskon, SS Bondarenko, EN Ostapchuk, ... Tetrahedron Letters 51 (32), 4229-4232, 2010 | 45 | 2010 |
A synthesis of 5-hetaryl-3-(2-hydroxybenzoyl) pyrroles AS Plaskon, SV Ryabukhin, DM Volochnyuk, AN Shivanyuk, ... Tetrahedron 64 (25), 5933-5943, 2008 | 43 | 2008 |
Catalytic undirected borylation of tertiary C–H bonds in bicyclo [1.1. 1] pentanes and bicyclo [2.1. 1] hexanes IF Yu, JL Manske, A Diéguez-Vázquez, A Misale, AE Pashenko, ... Nature chemistry 15 (5), 685-693, 2023 | 42 | 2023 |
Gram‐Scale Synthesis of Amines Bearing a gem‐Difluorocyclopropane Moiety PS Nosik, AO Gerasov, RO Boiko, E Rusanov, SV Ryabukhin, ... Advanced Synthesis & Catalysis 359 (18), 3126-3136, 2017 | 42 | 2017 |