Robustness and Compensation of Information Transmission of Signaling Pathways S Uda, TH Saito, T Kudo, T Kokaji, T Tsuchiya, H Kubota, Y Komori, ... Science 341 (6145), 558-561, 2013 | 159 | 2013 |
Robustness of MEK-ERK Dynamics and Origins of Cell-to-Cell Variability in MAPK Signaling S Filippi, CP Barnes, PDW Kirk, T Kudo, K Kunida, SS McMahon, ... Cell Reports 15 (11), 2524-2535, 2016 | 69 | 2016 |
Temporal Decoding of MAP Kinase and CREB Phosphorylation by Selective Immediate Early Gene Expression TH Saito, S Uda, T Tsuchiya, Y Ozaki, S Kuroda PLoS ONE 8 (3), e57037, 2013 | 33 | 2013 |
Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle R Egami, T Kokaji, A Hatano, K Yugi, M Eto, K Morita, S Ohno, M Fujii, ... IScience 24 (3), 2021 | 19 | 2021 |
Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity T Kokaji, A Hatano, Y Ito, K Yugi, M Eto, K Morita, S Ohno, M Fujii, ... Science Signaling 13 (660), eaaz1236, 2020 | 19 | 2020 |
Stability of RNA sequences derived from the coronavirus genome in human cells H Wakida, K Kawata, Y Yamaji, E Hattori, T Tsuchiya, Y Wada, H Ozaki, ... Biochemical and Biophysical Research Communications 527 (4), 993-999, 2020 | 18 | 2020 |
System Identification of Signaling Dependent Gene Expression with Different Time-Scale Data T Tsuchiya, M Fujii, N Matsuda, K Kunida, S Uda, H Kubota, K Konishi, ... PLoS Computational Biology 13 (12), e1005913, 2017 | 7 | 2017 |
CCPLS reveals cell-type-specific spatial dependence of transcriptomes in single cells T Tsuchiya, H Hori, H Ozaki Bioinformatics 38 (21), 4868-4877, 2022 | 3 | 2022 |
DNA hypomethylation characterizes genes encoding tissue-dominant functional proteins in liver and skeletal muscle H Maehara, T Kokaji, A Hatano, Y Suzuki, M Matsumoto, KI Nakayama, ... Scientific reports 13 (1), 19118, 2023 | 2 | 2023 |
Identifying potential regulators of JAGGED1 expression in portal mesenchymal cells T Nishino, M Yoshihara, T Nakayama, T Tsuchiya, S Tahara, H Ozaki, ... BMC Research Notes 15 (1), 172, 2022 | 2 | 2022 |
Laguerre Filter Analysis with Partial Least Square Regression Reveals a Priming Effect of ERK and CREB on c-FOS Induction T Kudo, S Uda, T Tsuchiya, T Wada, Y Karasawa, M Fujii, TH Saito, ... PLoS ONE 11 (8), e0160548, 2016 | 2 | 2016 |
Origins of Cell-to-Cell Variability, Kinetic Proof-Reading and the Robustness of MAPK Signal Transduction S Filippi, C Barnes, P Kirk, T Kudo, S McMahon, T Tsuchiya, T Wada, ... bioRxiv, 021790, 2015 | 2 | 2015 |
The RNA-binding protein Msi2 regulates autophagy during myogenic differentiation R Wang, F Kato, RY Watson, AM Beedle, JA Call, Y Tsunoda, T Noda, ... Life Science Alliance 7 (5), 2024 | | 2024 |
Structural robustness and temporal vulnerability of the starvation-responsive metabolic network in liver of healthy and obese mice K Morita, A Hatano, T Kokaji, H Sugimoto, T Tsuchiya, H Ozaki, R Egami, ... bioRxiv, 2024.06. 17.599249, 2024 | | 2024 |
Transcription factor-binding k-mer analysis clarifies the cell type dependency of binding specificities and cis-regulatory SNPs in humans S Tahara, T Tsuchiya, H Matsumoto, H Ozaki BMC genomics 24 (1), 597, 2023 | | 2023 |
CCPLS reveals cell-type-specific spatial dependence of transcriptomes in single cells (vol 38, pg 4868, 2022) T Tsuchiya, H Hori, H Ozaki BIOINFORMATICS 39 (2), 2023 | | 2023 |
In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states T Kokaji, M Eto, A Hatano, K Yugi, K Morita, S Ohno, M Fujii, K Hironaka, ... Scientific reports 12 (1), 13719, 2022 | | 2022 |
MOCCS profile analysis clarifies the cell type dependency of transcription factor-binding sequences and cis-regulatory SNPs in humans S Tahara, T Tsuchiya, H Matsumoto, H Ozaki bioRxiv, 2022.04. 08.487641, 2022 | | 2022 |
ゲノム編集技術と大規模ゲノムデータに基づいた遺伝子治療の展望 土屋貴穂 PrecisionMedicine 4 (2), 167-171, 2021 | | 2021 |
集団ゲノムデータから展望する遺伝子治療とプレシジョンメディシンの動向 土屋貴穂 Precision Medicine 3 (10), 930-934, 2020 | | 2020 |