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SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function ES Winkler, AL Bailey, NM Kafai, S Nair, BT McCune, J Yu, JM Fox, ... Nature immunology 21 (11), 1327-1335, 2020 | 838 | 2020 |
A SARS-CoV-2 infection model in mice demonstrates protection by neutralizing antibodies AO Hassan, JB Case, ES Winkler, LB Thackray, NM Kafai, AL Bailey, ... Cell 182 (3), 744-753. e4, 2020 | 521 | 2020 |
A single-dose intranasal ChAd vaccine protects upper and lower respiratory tracts against SARS-CoV-2 AO Hassan, NM Kafai, IP Dmitriev, JM Fox, BK Smith, IB Harvey, RE Chen, ... Cell 183 (1), 169-184. e13, 2020 | 514 | 2020 |
The antigenic anatomy of SARS-CoV-2 receptor binding domain W Dejnirattisai, D Zhou, HM Ginn, HME Duyvesteyn, P Supasa, JB Case, ... Cell 184 (8), 2183-2200. e22, 2021 | 363 | 2021 |
Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis in mice JB Case, PW Rothlauf, RE Chen, NM Kafai, JM Fox, BK Smith, S Shrihari, ... Cell host & microbe 28 (3), 465-474. e4, 2020 | 186 | 2020 |
A potently neutralizing antibody protects mice against SARS-CoV-2 infection WB Alsoussi, JS Turner, JB Case, H Zhao, AJ Schmitz, JQ Zhou, RE Chen, ... The Journal of Immunology 205 (4), 915-922, 2020 | 185 | 2020 |
Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread RL Lamason, E Bastounis, NM Kafai, R Serrano, JC del Álamo, JA Theriot, ... Cell 167 (3), 670-683. e10, 2016 | 106 | 2016 |
LDLRAD3 is a receptor for Venezuelan equine encephalitis virus H Ma, AS Kim, NM Kafai, JT Earnest, AP Shah, JB Case, K Basore, ... Nature 588 (7837), 308-314, 2020 | 97 | 2020 |
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice AC Hunt, JB Case, YJ Park, L Cao, K Wu, AC Walls, Z Liu, JE Bowen, ... Science translational medicine 14 (646), eabn1252, 2022 | 77 | 2022 |
Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains B Ying, B Whitener, LA VanBlargan, AO Hassan, S Shrihari, CY Liang, ... Science translational medicine 14 (630), eabm3302, 2021 | 69 | 2021 |
Genome-wide siRNA screen identifies complementary signaling pathways involved in Listeria infection and reveals different actin nucleation mechanisms during Listeria cell … A Kühbacher, M Emmenlauer, P Rämo, N Kafai, C Dehio, P Cossart, ... MBio 6 (3), 10.1128/mbio. 00598-15, 2015 | 68 | 2015 |
Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope AS Kim, NM Kafai, ES Winkler, TC Gilliland, EL Cottle, JT Earnest, ... Cell 184 (17), 4414-4429. e19, 2021 | 48 | 2021 |
Ultrapotent miniproteins targeting the SARS-CoV-2 receptor-binding domain protect against infection and disease JB Case, RE Chen, L Cao, B Ying, ES Winkler, M Johnson, I Goreshnik, ... Cell host & microbe 29 (7), 1151-1161. e5, 2021 | 45 | 2021 |
Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor K Basore, H Ma, NM Kafai, S Mackin, AS Kim, CA Nelson, MS Diamond, ... Nature 598 (7882), 672-676, 2021 | 35 | 2021 |
A streamlined method for transposon mutagenesis of Rickettsia parkeri yields numerous mutations that impact infection RL Lamason, NM Kafai, MD Welch PloS one 13 (5), e0197012, 2018 | 30 | 2018 |
Malaria in children NM Kafai, ARO John Infectious disease clinics of North America 32 (1), 189-200, 2018 | 28 | 2018 |
Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses LA VanBlargan, JM Errico, NM Kafai, KE Burgomaster, PN Jethva, ... Journal of Experimental Medicine 218 (5), e20210174, 2021 | 25 | 2021 |
Suppression of drug resistance reveals a genetic mechanism of metabolic plasticity in malaria parasites AM Guggisberg, PM Frasse, AJ Jezewski, NM Kafai, AY Gandhi, ... MBio 9 (6), 10.1128/mbio. 01193-18, 2018 | 22 | 2018 |
Entry receptors—the gateway to alphavirus infection O Zimmerman, AC Holmes, NM Kafai, LJ Adams, MS Diamond The Journal of Clinical Investigation 133 (2), 2023 | 21 | 2023 |