Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline K Talbot, HY Wang, H Kazi, LY Han, KP Bakshi, A Stucky, RL Fuino, ... The Journal of clinical investigation 122 (4), 1316-1338, 2012 | 1853 | 2012 |
Gene expression elucidates functional impact of polygenic risk for schizophrenia M Fromer, P Roussos, SK Sieberts, JS Johnson, DH Kavanagh, ... Nature neuroscience 19 (11), 1442-1453, 2016 | 1075 | 2016 |
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers TR Bomfim, L Forny-Germano, LB Sathler, J Brito-Moreira, JC Houzel, ... The Journal of clinical investigation 122 (4), 1339-1353, 2012 | 919 | 2012 |
Altered neuregulin 1–erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia CG Hahn, HY Wang, DS Cho, K Talbot, RE Gur, WH Berrettini, K Bakshi, ... Nature medicine 12 (7), 824-828, 2006 | 692 | 2006 |
Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia K Talbot, WL Eidem, CL Tinsley, MA Benson, EW Thompson, RJ Smith, ... The Journal of clinical investigation 113 (9), 1353-1363, 2004 | 540 | 2004 |
Acetylcholinesterase neurons in dopamine-containing regions of the brain LL Butcher, K Talbot, L Bilezikjian Journal of neural transmission 37, 127-153, 1975 | 257 | 1975 |
Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease N Louneva, JW Cohen, LY Han, K Talbot, RS Wilson, DA Bennett, ... The American journal of pathology 173 (5), 1488-1495, 2008 | 237 | 2008 |
Neurodevelopment, neuroplasticity, and new genes for schizophrenia SE Arnold, K Talbot, CG Hahn Progress in brain research 147, 319-345, 2005 | 201 | 2005 |
Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin K Talbot, DS Cho, WY Ong, MA Benson, LY Han, HA Kazi, J Kamins, ... Human molecular genetics 15 (20), 3041-3054, 2006 | 166 | 2006 |
Association of anxiety and depression with microtubule-associated protein 2–and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans A Soetanto, RS Wilson, K Talbot, A Un, JA Schneider, M Sobiesk, J Kelly, ... Archives of general psychiatry 67 (5), 448-457, 2010 | 146 | 2010 |
The nature, significance, and glucagon‐like peptide‐1 analog treatment of brain insulin resistance in Alzheimer's disease K Talbot, HY Wang Alzheimer's & Dementia 10, S12-S25, 2014 | 141 | 2014 |
Landscape of conditional eQTL in dorsolateral prefrontal cortex and co-localization with schizophrenia GWAS A Dobbyn, LM Huckins, J Boocock, LG Sloofman, BS Glicksberg, ... The American Journal of Human Genetics 102 (6), 1169-1184, 2018 | 140 | 2018 |
Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression J Tang, RP LeGros, N Louneva, L Yeh, JW Cohen, CG Hahn, DJ Blake, ... Human molecular genetics 18 (20), 3851-3863, 2009 | 140 | 2009 |
Age-dependent synuclein pathology following traumatic brain injury in mice K Uryu, BI Giasson, L Longhi, D Martinez, I Murray, V Conte, M Nakamura, ... Experimental neurology 184 (1), 214-224, 2003 | 139 | 2003 |
Neurobehavioral abnormalities in the dysbindin‐1 mutant, sandy, on a C57BL/6J genetic background MM Cox, AM Tucker, J Tang, K Talbot, DC Richer, L Yeh, SE Arnold Genes, Brain and Behavior 8 (4), 390-397, 2009 | 124 | 2009 |
Brain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogs K Talbot Neurodegenerative disease management 4 (1), 31-40, 2014 | 117 | 2014 |
Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia GC Carlson, K Talbot, TB Halene, MJ Gandal, HA Kazi, L Schlosser, ... Proceedings of the National Academy of Sciences 108 (43), E962-E970, 2011 | 115 | 2011 |
Measuring cell-type specific differential methylation in human brain tissue CM Montaño, RA Irizarry, WE Kaufmann, K Talbot, RE Gur, AP Feinberg, ... Genome biology 14, 1-9, 2013 | 114 | 2013 |
Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function DT Balu, GC Carlson, K Talbot, H Kazi, TE Hill‐Smith, RM Easton, ... Hippocampus 22 (2), 230-240, 2012 | 104 | 2012 |
Cholinergic–Monoaminergic Interactions in the Brain L Butcher Elsevier, 2012 | 99 | 2012 |