The genetic basis of early T-cell precursor acute lymphoblastic leukaemia J Zhang, L Ding, L Holmfeldt, G Wu, SL Heatley, D Payne-Turner, ... Nature 481 (7380), 157-163, 2012 | 1800 | 2012 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1723* | 2020 |
Hematopoiesis: a human perspective S Doulatov, F Notta, E Laurenti, JE Dick Cell stem cell 10 (2), 120-136, 2012 | 1172 | 2012 |
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment F Notta, S Doulatov, E Laurenti, A Poeppl, I Jurisica, JE Dick Science 333 (6039), 218-221, 2011 | 1071 | 2011 |
Distinct routes of lineage development reshape the human blood hierarchy across ontogeny F Notta, S Zandi, N Takayama, S Dobson, OI Gan, G Wilson, ... Science 351 (6269), aab2116, 2016 | 854 | 2016 |
Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer A Kreso, CA O'Brien, P Van Galen, OI Gan, F Notta, AMK Brown, K Ng, ... Science 339 (6119), 543-548, 2013 | 854 | 2013 |
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 806 | 2018 |
Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development S Doulatov, F Notta, K Eppert, LT Nguyen, PS Ohashi, JE Dick Nature immunology 11 (7), 585-593, 2010 | 669 | 2010 |
Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells F Notta, CG Mullighan, JCY Wang, A Poeppl, S Doulatov, LA Phillips, ... Nature 469 (7330), 362-367, 2011 | 598 | 2011 |
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ... Nature 538 (7625), 378-382, 2016 | 561 | 2016 |
Genomics-driven precision medicine for advanced pancreatic cancer: early results from the COMPASS trial KL Aung, SE Fischer, RE Denroche, GH Jang, A Dodd, S Creighton, ... Clinical Cancer Research 24 (6), 1344-1354, 2018 | 493 | 2018 |
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution M Chan-Seng-Yue, JC Kim, GW Wilson, K Ng, EF Figueroa, GM O’Kane, ... Nature genetics 52 (2), 231-240, 2020 | 454 | 2020 |
Childhood cerebellar tumours mirror conserved fetal transcriptional programs MC Vladoiu, I El-Hamamy, LK Donovan, H Farooq, BL Holgado, ... Nature 572 (7767), 67-73, 2019 | 364 | 2019 |
A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal M Milyavsky, OI Gan, M Trottier, M Komosa, O Tabach, F Notta, ... Cell stem cell 7 (2), 186-197, 2010 | 324 | 2010 |
Association of distinct mutational signatures with correlates of increased immune activity in pancreatic ductal adenocarcinoma AA Connor, RE Denroche, GH Jang, L Timms, SN Kalimuthu, I Selander, ... JAMA oncology 3 (6), 774-783, 2017 | 256 | 2017 |
GATA6 expression distinguishes classical and basal-like subtypes in advanced pancreatic cancer GM O’Kane, BT Grünwald, GH Jang, M Masoomian, S Picardo, RC Grant, ... Clinical Cancer Research 26 (18), 4901-4910, 2020 | 230 | 2020 |
Spatially confined sub-tumor microenvironments in pancreatic cancer BT Grünwald, A Devisme, G Andrieux, F Vyas, K Aliar, CW McCloskey, ... Cell 184 (22), 5577-5592. e18, 2021 | 227 | 2021 |
Efficacy of retinoids in IKZF1-mutated BCR-ABL1 acute lymphoblastic leukemia ML Churchman, J Low, C Qu, EM Paietta, LH Kasper, Y Chang, ... Cancer cell 28 (3), 343-356, 2015 | 192 | 2015 |
Engraftment of human hematopoietic stem cells is more efficient in female NOD/SCID/IL-2Rgc-null recipients F Notta, S Doulatov, JE Dick Blood, The Journal of the American Society of Hematology 115 (18), 3704-3707, 2010 | 180 | 2010 |
Integration of genomic and transcriptional features in pancreatic cancer reveals increased cell cycle progression in metastases AA Connor, RE Denroche, GH Jang, M Lemire, A Zhang, ... Cancer cell 35 (2), 267-282. e7, 2019 | 174 | 2019 |