Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise-regulated kinases and AMPK substrates NJ Hoffman, BL Parker, R Chaudhuri, KH Fisher-Wellman, M Kleinert, ... Cell metabolism 22 (5), 922-935, 2015 | 401 | 2015 |
Inhibition of PKCɛ improves glucose-stimulated insulin secretion and reduces insulin clearance C Schmitz-Peiffer, DR Laybutt, JG Burchfield, E Gurisik, S Narasimhan, ... Cell metabolism 6 (4), 320-328, 2007 | 129 | 2007 |
Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation DJ Fazakerley, AY Minard, JR Krycer, KC Thomas, J Stöckli, DJ Harney, ... Journal of Biological Chemistry 293 (19), 7315-7328, 2018 | 128 | 2018 |
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance DJ Fazakerley, R Chaudhuri, P Yang, GJ Maghzal, KC Thomas, JR Krycer, ... Elife 7, e32111, 2018 | 117 | 2018 |
Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C θ JG Burchfield, AJ Lennard, S Narasimhan, WE Hughes, VC Wasinger, ... Journal of Biological Chemistry 279 (18), 18623-18632, 2004 | 107 | 2004 |
Identification of a distal GLUT4 trafficking event controlled by actin polymerization JA Lopez, JG Burchfield, DH Blair, K Mele, Y Ng, P Vallotton, DE James, ... Molecular biology of the cell 20 (17), 3918-3929, 2009 | 95 | 2009 |
Variations in the requirement for v-SNAREs in GLUT4 trafficking in adipocytes P Zhao, L Yang, JA Lopez, J Fan, JG Burchfield, L Bai, W Hong, T Xu, ... Journal of cell science 122 (19), 3472-3480, 2009 | 89 | 2009 |
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt Z Su, JG Burchfield, P Yang, SJ Humphrey, G Yang, D Francis, S Yasmin, ... Nature communications 10 (1), 5486, 2019 | 88 | 2019 |
High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice JG Burchfield, MA Kebede, CC Meoli, J Stöckli, PT Whitworth, AL Wright, ... Journal of biological chemistry 293 (15), 5731-5745, 2018 | 83 | 2018 |
Exocytotic vesicle behaviour assessed by total internal reflection fluorescence microscopy JG Burchfield, JA Lopez, K Mele, P Vallotton, WE Hughes Traffic 11 (4), 429-439, 2010 | 83 | 2010 |
The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 … SX Tan, Y Ng, JG Burchfield, G Ramm, DG Lambright, J Stöckli, ... Molecular and cellular biology 32 (24), 4946-4959, 2012 | 82 | 2012 |
Diverse roles for protein kinase C δ and protein kinase C ε in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C δ G Frangioudakis, JG Burchfield, S Narasimhan, GJ Cooney, M Leitges, ... Diabetologia 52, 2616-2620, 2009 | 78 | 2009 |
Deletion of PKCε selectively enhances the amplifying pathways of glucose-stimulated insulin secretion via increased lipolysis in mouse β-cells J Cantley, JG Burchfield, GL Pearson, C Schmitz-Peiffer, M Leitges, ... Diabetes 58 (8), 1826-1834, 2009 | 65 | 2009 |
Multiplexed temporal quantification of the exercise-regulated plasma peptidome BL Parker, JG Burchfield, D Clayton, TA Geddes, RJ Payne, B Kiens, ... Molecular & Cellular Proteomics 16 (12), 2055-2068, 2017 | 63 | 2017 |
Proteomic analysis of GLUT4 storage vesicles reveals tumor suppressor candidate 5 (TUSC5) as a novel regulator of insulin action in adipocytes DJ Fazakerley, S Naghiloo, R Chaudhuri, F Koumanov, JG Burchfield, ... Journal of Biological Chemistry 290 (39), 23528-23542, 2015 | 59 | 2015 |
Phosphoproteomics reveals conserved exercise‐stimulated signaling and AMPK regulation of store‐operated calcium entry ME Nelson, BL Parker, JG Burchfield, NJ Hoffman, EJ Needham, ... The EMBO journal 38 (24), e102578, 2019 | 58 | 2019 |
Cluster analysis of insulin action in adipocytes reveals a key role for Akt at the plasma membrane Y Ng, G Ramm, JG Burchfield, ACF Coster, J Stöckli, DE James Journal of biological chemistry 285 (4), 2245-2257, 2010 | 57 | 2010 |
Autoencoder-based cluster ensembles for single-cell RNA-seq data analysis TA Geddes, T Kim, L Nan, JG Burchfield, JYH Yang, D Tao, P Yang BMC bioinformatics 20, 1-11, 2019 | 53 | 2019 |
DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake J Li, J Cantley, JG Burchfield, CC Meoli, J Stöckli, PT Whitworth, H Pant, ... Diabetologia 57, 2173-2182, 2014 | 46 | 2014 |
Systemic VEGF-A neutralization ameliorates diet-induced metabolic dysfunction LE Wu, CC Meoli, SP Mangiafico, DJ Fazakerley, VC Cogger, ... Diabetes 63 (8), 2656-2667, 2014 | 40 | 2014 |