Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases RM Meganck, RS Baric Nature medicine 27 (3), 401-410, 2021 | 182 | 2021 |
The current and future state of vaccines, antivirals and gene therapies against emerging coronaviruses LV Tse, RM Meganck, RL Graham, RS Baric Frontiers in microbiology 11, 658, 2020 | 109 | 2020 |
Tissue-dependent expression and translation of circular RNAs with recombinant AAV vectors in vivo RM Meganck, EK Borchardt, RMC Rivera, ML Scalabrino, JE Wilusz, ... Molecular Therapy-Nucleic Acids 13, 89-98, 2018 | 108 | 2018 |
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice A Schäfer, DR Martinez, JJ Won, RM Meganck, FR Moreira, AJ Brown, ... Science Translational Medicine 14 (643), eabm3410, 2022 | 56 | 2022 |
Engineering highly efficient backsplicing and translation of synthetic circRNAs RM Meganck, J Liu, AE Hale, KE Simon, MM Fanous, HA Vincent, ... Molecular Therapy-Nucleic Acids, 2021 | 53 | 2021 |
Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus A Das, R Barrientos, T Shiota, V Madigan, I Misumi, KL McKnight, L Sun, ... Nature microbiology 5 (9), 1069-1078, 2020 | 50 | 2020 |
Durability of heterologous and homologous COVID-19 vaccine boosts CS Tan, YC Ai-ris, J Yu, J Liu, A Chandrashekar, K McMahan, ... JAMA network open 5 (8), e2226335-e2226335, 2022 | 49 | 2022 |
Coevolution of adeno-associated virus capsid antigenicity and tropism through a structure-guided approach LP Havlik, KE Simon, JK Smith, KA Klinc, LV Tse, DK Oh, MM Fanous, ... Journal of Virology 94 (19), 10.1128/jvi. 00976-20, 2020 | 47 | 2020 |
Mapping and engineering functional domains of the assembly-activating protein of adeno-associated viruses LV Tse, S Moller-Tank, RM Meganck, A Asokan Journal of virology 92 (14), 10.1128/jvi. 00393-18, 2018 | 41 | 2018 |
Inducing circular RNA formation using the CRISPR endoribonuclease Csy4 EK Borchardt, RM Meganck, HA Vincent, CB Ball, SBV Ramos, ... Rna 23 (5), 619-627, 2017 | 31 | 2017 |
Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription VJ Madigan, JA Yuziuk, AM Chiarella, TO Tyson, RM Meganck, ... PLoS pathogens 15 (8), e1007988, 2019 | 25 | 2019 |
Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2 RJ Hagey, M Elazar, EA Pham, S Tian, L Ben-Avi, C Bernardin-Souibgui, ... Nature medicine 28 (9), 1944-1955, 2022 | 20 | 2022 |
Genomewide CRISPR knockout screen identified PLAC8 as an essential factor for SADS-CoVs infection LV Tse, RM Meganck, KC Araba, BL Yount, KM Shaffer, YJ Hou, JE Munt, ... Proceedings of the National Academy of Sciences 119 (18), e2118126119, 2022 | 20 | 2022 |
Generation of mature DENVs via genetic modification and directed evolution LV Tse, RM Meganck, S Dong, LE Adams, LJ White, ML Mallory, R Jadi, ... MBio 13 (3), e00386-22, 2022 | 12* | 2022 |
Impact of RNA structure on ZFP36L2 interaction with luteinizing hormone receptor mRNA CB Ball, AC Solem, RM Meganck, A Laederach, SBV Ramos RNA 23 (8), 1209-1223, 2017 | 11 | 2017 |
Host range, transmissibility and antigenicity of a pangolin coronavirus YJ Hou, S Chiba, SR Leist, RM Meganck, DR Martinez, A Schäfer, ... Nature Microbiology 8 (10), 1820-1833, 2023 | 10 | 2023 |
A live dengue virus vaccine carrying a chimeric envelope glycoprotein elicits dual DENV2-DENV4 serotype-specific immunity E Young, B Yount, P Pantoja, S Henein, RM Meganck, J McBride, JE Munt, ... Nature communications 14 (1), 1371, 2023 | 9 | 2023 |
A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus LV Tse, YJ Hou, E McFadden, RE Lee, TD Scobey, SR Leist, DR Martinez, ... Science Translational Medicine 15 (715), eadg5567, 2023 | 5 | 2023 |
Knockouts of TUT7 and 3′ hExo show that they cooperate in histone mRNA maintenance and degradation CE Holmquist, W He, RM Meganck, WF Marzluff RNA 28 (11), 1519-1533, 2022 | 1 | 2022 |
SARS-CoV-2 variant of concern fitness and adaptation in primary human airway epithelia RM Meganck, CE Edwards, ML Mallory, RE Lee, H Dang, AB Bailey, ... Cell Reports 43 (4), 2024 | | 2024 |