2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity PL Sulkowski, CD Corso, ND Robinson, SE Scanlon, KR Purshouse, ... Science translational medicine 9 (375), eaal2463, 2017 | 524 | 2017 |
Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection J Wei, MM Alfajaro, PC DeWeirdt, RE Hanna, WJ Lu-Culligan, WL Cai, ... Cell 184 (1), 76-91. e13, 2021 | 456 | 2021 |
Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes YV Surovtseva, D Churikov, KA Boltz, X Song, JC Lamb, R Warrington, ... Molecular cell 36 (2), 207-218, 2009 | 340 | 2009 |
The Arabidopsis Pot1 and Pot2 Proteins Function in Telomere Length Homeostasis and Chromosome End Protection EV Shakirov, YV Surovtseva, N Osbun, DE Shippen Molecular and cellular biology 25 (17), 7725-7733, 2005 | 164 | 2005 |
Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance YV Surovtseva, EV Shakirov, L Vespa, N Osbun, X Song, DE Shippen The EMBO journal 26 (15), 3653-3661, 2007 | 119 | 2007 |
Determinants of mammalian nucleolar architecture KI Farley, Y Surovtseva, J Merkel, SJ Baserga Chromosoma 124, 323-331, 2015 | 118 | 2015 |
Diverse regulators of human ribosome biogenesis discovered by changes in nucleolar number KI Farley-Barnes, KL McCann, LM Ogawa, J Merkel, YV Surovtseva, ... Cell reports 22 (7), 1923-1934, 2018 | 115 | 2018 |
STN1 protects chromosome ends in Arabidopsis thaliana X Song, K Leehy, RT Warrington, JC Lamb, YV Surovtseva, DE Shippen Proceedings of the National Academy of Sciences 105 (50), 19815-19820, 2008 | 115 | 2008 |
A C-terminal Myb extension domain defines a novel family of double-strand telomeric DNA-binding proteins in Arabidopsis ZN Karamysheva, YV Surovtseva, L Vespa, EV Shakirov, DE Shippen Journal of Biological Chemistry 279 (46), 47799-47807, 2004 | 115 | 2004 |
Restriction of SARS-CoV-2 replication by targeting programmed− 1 ribosomal frameshifting Y Sun, L Abriola, RO Niederer, SF Pedersen, MM Alfajaro, ... Proceedings of the National Academy of Sciences 118 (26), e2023051118, 2021 | 106 | 2021 |
Mitochondrial ribosomal protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription YV Surovtseva, TE Shutt, J Cotney, H Cimen, SY Chen, EC Koc, ... Proceedings of the National Academy of Sciences 108 (44), 17921-17926, 2011 | 91 | 2011 |
PKCε contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling BM Gassaway, MC Petersen, YV Surovtseva, KW Barber, JB Sheetz, ... Proceedings of the National Academy of Sciences 115 (38), E8996-E9005, 2018 | 75 | 2018 |
Complement membrane attack complexes activate noncanonical NF-κB by forming an Akt+ NIK+ signalosome on Rab5+ endosomes D Jane-wit, YV Surovtseva, L Qin, G Li, R Liu, P Clark, TD Manes, C Wang, ... Proceedings of the National Academy of Sciences 112 (31), 9686-9691, 2015 | 71 | 2015 |
Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection J Wei, MM Alfajaro, RE Hanna, PC DeWeirdt, MS Strine, WJ Lu-Culligan, ... Biorxiv, 2020 | 64 | 2020 |
LRP130 protein remodels mitochondria and stimulates fatty acid oxidation L Liu, M Sanosaka, S Lei, ML Bestwick, JH Frey, YV Surovtseva, ... Journal of Biological Chemistry 286 (48), 41253-41264, 2011 | 57 | 2011 |
Characterization of cardiac glycoside natural products as potent inhibitors of DNA double-strand break repair by a whole-cell double immunofluorescence assay YV Surovtseva, V Jairam, AF Salem, RK Sundaram, RS Bindra, ... Journal of the American Chemical Society 138 (11), 3844-3855, 2016 | 52 | 2016 |
Mitochondrial ribosomal protein L12 is required for POLRMT stability and exists as two forms generated by alternative proteolysis during import J Nouws, AV Goswami, M Bestwick, BJ McCann, YV Surovtseva, ... Journal of Biological Chemistry 291 (2), 989-997, 2016 | 50 | 2016 |
Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis YV Surovtseva, GS Shadel Nucleic acids research 41 (4), 2479-2488, 2013 | 46 | 2013 |
Increased numbers of nucleoli in a genome-wide RNAi screen reveal proteins that link the cell cycle to RNA polymerase I transcription LM Ogawa, AF Buhagiar, L Abriola, BA Leland, YV Surovtseva, ... Molecular biology of the cell 32 (9), 956-973, 2021 | 28 | 2021 |
Combined HMG-COA reductase and prenylation inhibition in treatment of CCM S Nishimura, K Mishra-Gorur, JS Park, YV Surovtseva, SM Sebti, ... Proceedings of the National Academy of Sciences 114 (21), 5503-5508, 2017 | 28 | 2017 |