Nuclear receptors and the regulation of drug‐metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs BL Urquhart, RG Tirona, RB Kim The Journal of Clinical Pharmacology 47 (5), 566-578, 2007 | 453 | 2007 |
Pre–B-Cell Colony–Enhancing Factor Regulates NAD+-Dependent Protein Deacetylase Activity and Promotes Vascular Smooth Muscle Cell Maturation E van der Veer, Z Nong, C O’Neil, B Urquhart, D Freeman, JG Pickering Circulation research 97 (1), 25-34, 2005 | 301 | 2005 |
Human skeletal muscle drug transporters determine local exposure and toxicity of statins MJ Knauer, BL Urquhart, HE Meyer zu Schwabedissen, UI Schwarz, ... Circulation research 106 (2), 297-306, 2010 | 247 | 2010 |
Allogenic fecal microbiota transplantation in patients with nonalcoholic fatty liver disease improves abnormal small intestinal permeability: a randomized control trial L Craven, A Rahman, SN Parvathy, M Beaton, J Silverman, K Qumosani, ... Official journal of the American College of Gastroenterology| ACG 115 (7 …, 2020 | 245 | 2020 |
Blood− brain barrier transporters and response to CNS-active drugs BL Urquhart, RB Kim European journal of clinical pharmacology 65, 1063-1070, 2009 | 230 | 2009 |
Uremic toxins in the progression of chronic kidney disease and cardiovascular disease: mechanisms and therapeutic targets YJ Lim, NA Sidor, NC Tonial, A Che, BL Urquhart Toxins 13 (2), 142, 2021 | 174 | 2021 |
Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe BL Urquhart, JA Ware, RG Tirona, RH Ho, BF Leake, UI Schwarz, H Zaher, ... Pharmacogenetics and genomics 18 (5), 439-448, 2008 | 156 | 2008 |
Propofol neuroprotection in cerebral ischemia and its effects on low-molecular-weight antioxidants and skilled motor tasks NA Bayona, AW Gelb, Z Jiang, JX Wilson, BL Urquhart, DF Cechetto The Journal of the American Society of Anesthesiologists 100 (5), 1151-1159, 2004 | 143 | 2004 |
Reinstalling antitumor immunity by inhibiting tumor-derived immunosuppressive molecule IDO through RNA interference X Zheng, J Koropatnick, M Li, X Zhang, F Ling, X Ren, X Hao, H Sun, ... The Journal of Immunology 177 (8), 5639-5646, 2006 | 141 | 2006 |
Metabolic products of the intestinal microbiome and extremes of atherosclerosis C Bogiatzi, G Gloor, E Allen-Vercoe, G Reid, RG Wong, BL Urquhart, ... Atherosclerosis 273, 91-97, 2018 | 140 | 2018 |
Genomic signatures for paclitaxel and gemcitabine resistance in breast cancer derived by machine learning SN Dorman, K Baranova, JHM Knoll, BL Urquhart, G Mariani, ... Molecular oncology 10 (1), 85-100, 2016 | 122 | 2016 |
N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes H Moazzen, X Lu, NL Ma, TJ Velenosi, BL Urquhart, LJ Wisse, ... Cardiovascular diabetology 13, 1-13, 2014 | 111 | 2014 |
Silencing IDO in dendritic cells: a novel approach to enhance cancer immunotherapy in a murine breast cancer model X Zheng, J Koropatnick, D Chen, T Velenosi, H Ling, X Zhang, N Jiang, ... International journal of cancer 132 (4), 967-977, 2013 | 110 | 2013 |
Pharmacokinetic considerations in chronic kidney disease and patients requiring dialysis TJ Velenosi, BL Urquhart Expert opinion on drug metabolism & toxicology 10 (8), 1131-1143, 2014 | 80 | 2014 |
Effect of renal impairment on atherosclerosis: only partially mediated by homocysteine JD Spence, BL Urquhart, H Bang Nephrology Dialysis Transplantation 31 (6), 937-944, 2016 | 73 | 2016 |
Untargeted plasma and tissue metabolomics in rats with chronic kidney disease given AST-120 TJ Velenosi, A Hennop, DA Feere, A Tieu, AS Kucey, P Kyriacou, ... Scientific Reports 6 (1), 22526, 2016 | 70 | 2016 |
Effect of CKD and dialysis modality on exposure to drugs cleared by nonrenal mechanisms BKA Thomson, TD Nolin, TJ Velenosi, DA Feere, MJ Knauer, LJ Asher, ... American Journal of Kidney Diseases 65 (4), 574-582, 2015 | 69 | 2015 |
Down-regulation of hepatic CYP3A and CYP2C mediated metabolism in rats with moderate chronic kidney disease TJ Velenosi, AYN Fu, S Luo, H Wang, BL Urquhart Drug Metabolism and Disposition 40 (8), 1508-1514, 2012 | 68 | 2012 |
The human proton-coupled folate transporter (hPCFT): modulation of intestinal expression and function by drugs BL Urquhart, JC Gregor, N Chande, MJ Knauer, RG Tirona, RB Kim American Journal of Physiology-Gastrointestinal and Liver Physiology 298 (2 …, 2010 | 61 | 2010 |
Moderate renal impairment and toxic metabolites produced by the intestinal microbiome: dietary implications M Pignanelli, C Bogiatzi, G Gloor, E Allen-Vercoe, G Reid, BL Urquhart, ... Journal of Renal Nutrition 29 (1), 55-64, 2019 | 59 | 2019 |