Mesenchymal stem cells reduce colitis in mice via release of TSG6, independently of their localization to the intestine E Sala, M Genua, L Petti, A Anselmo, V Arena, J Cibella, L Zanotti, ... Gastroenterology 149 (1), 163-176. e20, 2015 | 269 | 2015 |
VEGF-C–dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease S D’alessio, C Correale, C Tacconi, A Gandelli, G Pietrogrande, ... The Journal of clinical investigation 124 (9), 3863-3878, 2014 | 227 | 2014 |
Multiple pathways of cell invasion are regulated by multiple families of serine proteases M Del Rosso, G Fibbi, M Pucci, S D'Alessio, A Del Rosso, L Magnelli, ... Clinical & experimental metastasis 19, 193-207, 2002 | 159 | 2002 |
Matrix metalloproteinase 12–dependent cleavage of urokinase receptor in systemic sclerosis microvascular endothelial cells results in impaired angiogenesis S D'Alessio, G Fibbi, M Cinelli, S Guiducci, A Del Rosso, F Margheri, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2004 | 153 | 2004 |
Vascular endothelial growth factor C disrupts the endothelial lymphatic barrier to promote colorectal cancer invasion C Tacconi, C Correale, A Gandelli, A Spinelli, E Dejana, S D’Alessio, ... Gastroenterology 148 (7), 1438-1451. e8, 2015 | 135 | 2015 |
Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism S D'Alessio, G Ferrari, K Cinnante, W Scheerer, AC Galloway, DF Roses, ... Journal of Biological Chemistry 283 (1), 87-99, 2008 | 133 | 2008 |
The urokinase receptor as an entertainer of signal transduction S D’Alessio, F Blasi Front Biosci 14, 4575-4587, 2009 | 124 | 2009 |
Revisiting fibrosis in inflammatory bowel disease: the gut thickens S D’Alessio, F Ungaro, D Noviello, S Lovisa, L Peyrin-Biroulet, S Danese Nature Reviews Gastroenterology & Hepatology 19 (3), 169-184, 2022 | 96 | 2022 |
An uncleavable uPAR mutant allows dissection of signaling pathways in uPA-dependent cell migration R Mazzieri, S D'Alessio, RK Kenmoe, L Ossowski, F Blasi Molecular biology of the cell 17 (1), 367-378, 2006 | 92 | 2006 |
Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases F Margheri, S D'alessio, S Serrati, M Pucci, F Annunziato, L Cosmi, ... Gene Therapy 12 (8), 702-714, 2005 | 89 | 2005 |
Metagenomic analysis of intestinal mucosa revealed a specific eukaryotic gut virome signature in early-diagnosed inflammatory bowel disease F Ungaro, L Massimino, F Furfaro, V Rimoldi, L Peyrin-Biroulet, ... Gut Microbes 10 (2), 149-158, 2019 | 83 | 2019 |
Activation of the VEGFC/VEGFR3 pathway induces tumor immune escape in colorectal cancer C Tacconi, F Ungaro, C Correale, V Arena, L Massimino, M Detmar, ... Cancer research 79 (16), 4196-4210, 2019 | 72 | 2019 |
The gut virome in inflammatory bowel disease pathogenesis: from metagenomics to novel therapeutic approaches F Ungaro, L Massimino, S D’Alessio, S Danese United European gastroenterology journal 7 (8), 999-1007, 2019 | 65 | 2019 |
Actors and factors in the resolution of intestinal inflammation: lipid mediators as a new approach to therapy in inflammatory bowel diseases F Ungaro, F Rubbino, S Danese, S D’Alessio Frontiers in immunology 8, 1331, 2017 | 65 | 2017 |
PDE4 inhibition and inflammatory bowel disease: a novel therapeutic avenue M Spadaccini, S D’Alessio, L Peyrin-Biroulet, S Danese International Journal of Molecular Sciences 18 (6), 1276, 2017 | 65 | 2017 |
Antisense oligodeoxynucleotides for urokinase‐plasminogen activator receptor have anti‐invasive and anti‐proliferative effects in vitro and inhibit spontaneous metastases of … S D'Alessio, F Margheri, M Pucci, A Del Rosso, BP Monia, M Bologna, ... International journal of cancer 110 (1), 125-133, 2004 | 60 | 2004 |
TREM-1 inhibition restores impaired autophagy activity and reduces colitis in mice T Kökten, S Gibot, P Lepage, S D’Alessio, J Hablot, NC Ndiaye, ... Journal of Crohn's and Colitis 12 (2), 230-244, 2018 | 58 | 2018 |
MFSD2A promotes endothelial generation of inflammation-resolving lipid mediators and reduces colitis in mice F Ungaro, C Tacconi, L Massimino, PA Corsetto, C Correale, P Fonteyne, ... Gastroenterology 153 (5), 1363-1377. e6, 2017 | 58 | 2017 |
uPAR-deficient mouse keratinocytes fail to produce EGFR-dependent laminin-5, affecting migration in vivo and in vitro S D'Alessio, L Gerasi, F Blasi Journal of cell science 121 (23), 3922-3932, 2008 | 57 | 2008 |
The urokinase plasminogen activator receptor (uPAR) controls macrophage phagocytosis in intestinal inflammation M Genua, S D'Alessio, J Cibella, A Gandelli, E Sala, C Correale, ... Gut 64 (4), 589-600, 2015 | 52 | 2015 |