| WHOPPA enables parallel assessment of leucine-rich repeat kinase 2 and glucocerebrosidase enzymatic activity in Parkinson’s disease monocytes RL Wallings, LP Hughes, HA Staley, ZD Simon, NR McFarland, ... Frontiers in cellular neuroscience 16, 892899, 2022 | 15 | 2022 |
| ASO-mediated knockdown or kinase inhibition of G2019S-Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages RL Wallings, JR Mark, HA Staley, DA Gillett, N Neighbarger, ... Molecular Therapy-Nucleic Acids 34, 2023 | 4 | 2023 |
| The R1441C-Lrrk2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner in mice RL Wallings, K McFarland, HA Staley, N Neighbarger, S Schaake, ... Science Translational Medicine 16 (772), eadl1535, 2024 | 1 | 2024 |
| Lack of neuroprotection after systemic administration of the soluble TNF inhibitor XPro1595 in an rAAV6-α-Syn+ PFFs-induced rat model for Parkinson's disease F Fredlund, C Fryklund, O Trujeque-Ramos, HA Staley, J Pardo, KC Luk, ... bioRxiv, 2024.10. 23.619575, 2024 | 1 | 2024 |
| The role of immune dysregulation of innate and adaptive immune cells in the prodromal and clinical stages of Parkinson’s disease JR Mark, RL Wallings, H Staley, MG Tansey Alzheimer's & Dementia 20, e085589, 2024 | | 2024 |
| Alzheimer’s disease-associated protective variant Plcg2-P522R modulates peripheral macrophage function in a sex-dimorphic manner HA Staley, JE Jernigan, MKL Bolen, AM Titus, N Neighbarger, C Cole, ... Journal of Neuroinflammation 21 (1), 280, 2024 | | 2024 |
| Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy V Joers, BC Murray, C McLaughlin, D Oliver, HE Staley, J Coronado, ... Journal of Neuroinflammation 21 (1), 240, 2024 | | 2024 |
| Peripheral Blood Immune Cells from Individuals with Parkinson’s Disease or Inflammatory Bowel Disease Share Deficits in Iron Storage and Transport that are Modulated by Non … MKL Bolen, BN Gomes, B Gill, KB Menees, H Staley, J Jernigan, ... bioRxiv, 2024 | | 2024 |
| RGS10 Attenuates Systemic Immune Dysregulation Induced by Chronic Inflammatory Stress JE Jernigan, HA Staley, Z Baty, ML Bolen, BN Gomes, J Holt, CL Cole, ... bioRxiv, 2024.10. 24.620078, 2024 | | 2024 |
| ASO-mediated knockdown of GPNMB in mutant-GRN and Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses R Wallings, DA Gillett, H Staley, S Mahn, J Mark, N Neighbarger, ... bioRxiv, 2024.07. 22.604676, 2024 | | 2024 |
| The R1441C-LRRK2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner RL Wallings, K McFarland, HA Staley, N Neighbarger, S Schaake, ... bioRxiv, 2023.10. 12.562063, 2023 | | 2023 |
