Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism K Arita, M Ariyoshi, H Tochio, Y Nakamura, M Shirakawa Nature 455 (7214), 818-821, 2008 | 571 | 2008 |
High-resolution multi-dimensional NMR spectroscopy of proteins in human cells K Inomata, A Ohno, H Tochio, S Isogai, T Tenno, I Nakase, T Takeuchi, ... Nature 458 (7234), 106-109, 2009 | 520 | 2009 |
Paramagnetic Relaxation-Based 19F MRI Probe To Detect Protease Activity S Mizukami, R Takikawa, F Sugihara, Y Hori, H Tochio, M Wälchli, ... Journal of the American Chemical Society 130 (3), 794-795, 2008 | 294 | 2008 |
Crystal structure of thymine DNA glycosylase conjugated to SUMO-1 D Baba, N Maita, JG Jee, Y Uchimura, H Saitoh, K Sugasawa, F Hanaoka, ... Nature 435 (7044), 979-982, 2005 | 279 | 2005 |
Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling H Ohnishi, H Tochio, Z Kato, KE Orii, A Li, T Kimura, H Hiroaki, N Kondo, ... Proceedings of the National Academy of Sciences 106 (25), 10260-10265, 2009 | 254 | 2009 |
Structural basis for distinct roles of Lys63‐and Lys48‐linked polyubiquitin chains T Tenno, K Fujiwara, H Tochio, K Iwai, EH Morita, H Hayashi, S Murata, ... Genes to Cells 9 (10), 865-875, 2004 | 251 | 2004 |
Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1 K Arita, S Isogai, T Oda, M Unoki, K Sugita, N Sekiyama, K Kuwata, ... Proceedings of the National Academy of Sciences 109 (32), 12950-12955, 2012 | 227 | 2012 |
Self-assembling nanoprobes that display off/on 19F nuclear magnetic resonance signals for protein detection and imaging Y Takaoka, T Sakamoto, S Tsukiji, M Narazaki, T Matsuda, H Tochio, ... Nature chemistry 1 (7), 557-561, 2009 | 225 | 2009 |
Real-time background-free selective imaging of fluorescent nanodiamonds in vivo R Igarashi, Y Yoshinari, H Yokota, T Sugi, F Sugihara, K Ikeda, H Sumiya, ... Nano letters 12 (11), 5726-5732, 2012 | 212 | 2012 |
Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide H Tochio, Q Zhang, P Mandal, M Li, M Zhang Nature structural biology 6 (5), 417-421, 1999 | 199 | 1999 |
In-cell NMR spectroscopy of proteins inside Xenopus laevis oocytes T Sakai, H Tochio, T Tenno, Y Ito, T Kokubo, H Hiroaki, M Shirakawa Journal of biomolecular NMR 36, 179-188, 2006 | 180 | 2006 |
Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95 JF Long, H Tochio, P Wang, JS Fan, C Sala, M Niethammer, M Sheng, ... Journal of molecular biology 327 (1), 203-214, 2003 | 179 | 2003 |
Intracellular phosphate serves as a signal for the regulation of the PHO pathway in Saccharomyces cerevisiae C Auesukaree, T Homma, H Tochio, M Shirakawa, Y Kaneko, ... Journal of Biological Chemistry 279 (17), 17289-17294, 2004 | 171 | 2004 |
Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain JS Fan, Q Zhang, H Tochio, M Li, M Zhang Journal of molecular biology 306 (1), 97-108, 2001 | 170 | 2001 |
Structure of the UBA domain of Dsk2p in complex with ubiquitin: molecular determinants for ubiquitin recognition A Ohno, JG Jee, K Fujiwara, T Tenno, N Goda, H Tochio, H Kobayashi, ... Structure 13 (4), 521-532, 2005 | 163 | 2005 |
An autoinhibitory mechanism for nonsyntaxin SNARE proteins revealed by the structure of Ykt6p H Tochio, MMK Tsui, DK Banfield, M Zhang Science 293 (5530), 698-702, 2001 | 160 | 2001 |
Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin S Isogai, D Morimoto, K Arita, S Unzai, T Tenno, J Hasegawa, Y Sou, ... Journal of Biological Chemistry 286 (36), 31864-31874, 2011 | 158 | 2011 |
Formation of nNOS/PSD-95 PDZ dimer requires a preformed β-finger structure from the nNOS PDZ domain H Tochio, YK Mok, Q Zhang, HM Kan, DS Bredt, M Zhang Journal of molecular biology 303 (3), 359-370, 2000 | 155 | 2000 |
Solution structure and backbone dynamics of the second PDZ domain of postsynaptic density-95 H Tochio, F Hung, M Li, DS Bredt, M Zhang Journal of molecular biology 295 (2), 225-237, 2000 | 141 | 2000 |
Distance Determination in Proteins inside Xenopus laevis Oocytes by Double Electron−Electron Resonance Experiments R Igarashi, T Sakai, H Hara, T Tenno, T Tanaka, H Tochio, M Shirakawa Journal of the American Chemical Society 132 (24), 8228-8229, 2010 | 139 | 2010 |