Inulin, a flexible oligosaccharide I: Review of its physicochemical characteristics MA Mensink, HW Frijlink, K van der Voort Maarschalk, WLJ Hinrichs Carbohydrate polymers 130, 405-419, 2015 | 499 | 2015 |
How sugars protect proteins in the solid state and during drying (review): Mechanisms of stabilization in relation to stress conditions MA Mensink, HW Frijlink, K van Der Voort Maarschalk, WLJ Hinrichs European Journal of Pharmaceutics and Biopharmaceutics 114, 288-295, 2017 | 457 | 2017 |
Development of stable influenza vaccine powder formulations: challenges and possibilities JP Amorij, A Huckriede, J Wilschut, HW Frijlink, WLJ Hinrichs Pharmaceutical research 25, 1256-1273, 2008 | 270 | 2008 |
Characterization of the molecular distribution of drugs in glassy solid dispersions at the nano-meter scale, using differential scanning calorimetry and gravimetric water … DJ Van Drooge, WLJ Hinrichs, MR Visser, HW Frijlink International journal of pharmaceutics 310 (1-2), 220-229, 2006 | 263 | 2006 |
Inulin glasses for the stabilization of therapeutic proteins WLJ Hinrichs, MG Prinsen, HW Frijlink International journal of pharmaceutics 215 (1-2), 163-174, 2001 | 243 | 2001 |
A comparison between spray drying and spray freeze drying to produce an influenza subunit vaccine powder for inhalation V Saluja, JP Amorij, JC Kapteyn, AH De Boer, HW Frijlink, WLJ Hinrichs Journal of Controlled Release 144 (2), 127-133, 2010 | 242 | 2010 |
A novel bottom–up process to produce drug nanocrystals: controlled crystallization during freeze-drying H De Waard, WLJ Hinrichs, HW Frijlink Journal of controlled release 128 (2), 179-183, 2008 | 226 | 2008 |
Thermosensitive polymers as carriers for DNA delivery WLJ Hinrichs, NME Schuurmans-Nieuwenbroek, P Van De Wetering, ... Journal of controlled release 60 (2-3), 249-259, 1999 | 224 | 1999 |
Pulmonary delivery of an inulin-stabilized influenza subunit vaccine prepared by spray-freeze drying induces systemic, mucosal humoral as well as cell-mediated immune responses … JP Amorij, V Saluja, AH Petersen, WLJ Hinrichs, A Huckriede, HW Frijlink Vaccine 25 (52), 8707-8717, 2007 | 215 | 2007 |
Unraveling protein stabilization mechanisms: Vitrification and water replacement in a glass transition temperature controlled system N Grasmeijer, M Stankovic, H de Waard, HW Frijlink, WLJ Hinrichs Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (4), 763-769, 2013 | 193 | 2013 |
Inulin, a flexible oligosaccharide. II: Review of its pharmaceutical applications MA Mensink, HW Frijlink, K van der Voort Maarschalk, WLJ Hinrichs Carbohydrate polymers 134, 418-428, 2015 | 178 | 2015 |
Polymeric formulations for drug release prepared by hot melt extrusion: application and characterization M Stanković, HW Frijlink, WLJ Hinrichs Drug Discovery Today 20 (7), 812-823, 2015 | 170 | 2015 |
Size and molecular flexibility of sugars determine the storage stability of freeze-dried proteins WF Tonnis, MA Mensink, A de Jager, K van der Voort Maarschalk, ... Molecular pharmaceutics 12 (3), 684-694, 2015 | 162 | 2015 |
Needle-free influenza vaccination JP Amorij, WLJ Hinrichs, HW Frijlink, JC Wilschut, A Huckriede The Lancet infectious diseases 10 (10), 699-711, 2010 | 159 | 2010 |
Towards tailored vaccine delivery: needs, challenges and perspectives JP Amorij, GFA Kersten, V Saluja, WF Tonnis, WLJ Hinrichs, B Slütter, ... Journal of Controlled Release 161 (2), 363-376, 2012 | 148 | 2012 |
Rational design of an influenza subunit vaccine powder with sugar glass technology: preventing conformational changes of haemagglutinin during freezing and freeze-drying JP Amorij, J Meulenaar, WLJ Hinrichs, T Stegmann, A Huckriede, ... Vaccine 25 (35), 6447-6457, 2007 | 144 | 2007 |
The choice of a suitable oligosaccharide to prevent aggregation of PEGylated nanoparticles during freeze thawing and freeze drying WLJ Hinrichs, FA Mancenido, NN Sanders, K Braeckmans, SC De Smedt, ... International journal of pharmaceutics 311 (1-2), 237-244, 2006 | 143 | 2006 |
Quality by design approach for optimizing the formulation and physical properties of extemporaneously prepared orodispersible films JC Visser, WMC Dohmen, WLJ Hinrichs, J Breitkreutz, HW Frijlink, ... International journal of pharmaceutics 485 (1-2), 70-76, 2015 | 132 | 2015 |
Improved dissolution behavior of lipophilic drugs by solid dispersions: the production process as starting point for formulation considerations P Srinarong, H de Waard, HW Frijlink, WLJ Hinrichs Expert opinion on drug delivery 8 (9), 1121-1140, 2011 | 129 | 2011 |
Orodispersible films in individualized pharmacotherapy: The development of a formulation for pharmacy preparations JC Visser, HJ Woerdenbag, S Crediet, E Gerrits, MA Lesschen, ... International journal of pharmaceutics 478 (1), 155-163, 2015 | 119 | 2015 |