Chemical genetics of Plasmodium falciparum WA Guiguemde, AA Shelat, D Bouck, S Duffy, GJ Crowther, PH Davis, ... Nature 465 (7296), 311-315, 2010 | 648 | 2010 |
A novel multiple-stage antimalarial agent that inhibits protein synthesis B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ... Nature 522 (7556), 315-320, 2015 | 440 | 2015 |
Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins CJ Lovitt, TB Shelper, VM Avery BMC cancer 18, 1-11, 2018 | 332 | 2018 |
Advanced cell culture techniques for cancer drug discovery CJ Lovitt, TB Shelper, VM Avery Biology 3 (2), 345-367, 2014 | 329 | 2014 |
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria MA Phillips, J Lotharius, K Marsh, J White, A Dayan, KL White, ... Science translational medicine 7 (296), 296ra111-296ra111, 2015 | 327 | 2015 |
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 295 | 2016 |
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ... Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014 | 262 | 2014 |
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors N Kato, E Comer, T Sakata-Kato, A Sharma, M Sharma, M Maetani, ... Nature 538 (7625), 344-349, 2016 | 252 | 2016 |
Quinolone-3-diarylethers: a new class of antimalarial drug A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... Science translational medicine 5 (177), 177ra37-177ra37, 2013 | 249 | 2013 |
Flinderoles A−C: Antimalarial Bis-indole Alkaloids from Flindersia Species LS Fernandez, MS Buchanan, AR Carroll, YJ Feng, RJ Quinn, VM Avery Organic letters 11 (2), 329-332, 2009 | 242 | 2009 |
Leishmaniasis drug discovery: recent progress and challenges in assay development B Zulfiqar, TB Shelper, VM Avery Drug discovery today 22 (10), 1516-1531, 2017 | 211 | 2017 |
Identification of inhibitors of Plasmodium falciparum gametocyte development S Duffy, VM Avery Malaria journal 12, 1-15, 2013 | 162 | 2013 |
Development and optimization of a novel 384-well anti-malarial imaging assay validated for high-throughput screening S Duffy, VM Avery The American journal of tropical medicine and hygiene 86 (1), 84, 2012 | 162 | 2012 |
3, 5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential Y Younis, F Douelle, TS Feng, DG Cabrera, CL Manach, AT Nchinda, ... Journal of medicinal chemistry 55 (7), 3479-3487, 2012 | 159 | 2012 |
Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum AB Vaidya, JM Morrisey, Z Zhang, S Das, TM Daly, TD Otto, NJ Spillman, ... Nature communications 5 (1), 5521, 2014 | 150 | 2014 |
Natural Products, Stylissadines A and B, Specific Antagonists of the P2X7 Receptor, an Important Inflammatory Target1 MS Buchanan, AR Carroll, R Addepalli, VM Avery, JNA Hooper, RJ Quinn The Journal of organic chemistry 72 (7), 2309-2317, 2007 | 137 | 2007 |
HBO1 is required for the maintenance of leukaemia stem cells L MacPherson, J Anokye, MM Yeung, EYN Lam, YC Chan, CF Weng, ... Nature 577 (7789), 266-270, 2020 | 128 | 2020 |
Screening the medicines for malaria venture pathogen box across multiple pathogens reclassifies starting points for open-source drug discovery S Duffy, ML Sykes, AJ Jones, TB Shelper, M Simpson, R Lang, ... Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00379-17, 2017 | 127 | 2017 |
Identification of MMV malaria box inhibitors of Plasmodium falciparum early-stage gametocytes using a luciferase-based high-throughput assay L Lucantoni, S Duffy, SH Adjalley, DA Fidock, VM Avery Antimicrobial agents and chemotherapy 57 (12), 6050-6062, 2013 | 121 | 2013 |
Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427 ML Sykes, VM Avery Am. J. Trop. Med. Hyg 81 (4), 665-674, 2009 | 115 | 2009 |