| γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes M Gaczynska, KL Rock, AL Goldberg Nature 365 (6443), 264-267, 1993 | 799 | 1993 |
| Covalent modification of the active site threonine of proteasomal β subunits and the Escherichia coli homolog HslV by a new class of inhibitors M Bogyo, JS McMaster, M Gaczynska, D Tortorella, AL Goldberg, ... Proceedings of the National Academy of Sciences 94 (13), 6629-6634, 1997 | 581 | 1997 |
| Altered peptidase and viral-specific T cell response in LMP2 mutant mice L Van Kaert, PG Ashton-Rickardt, M Eichelberger, M Gaczynska, ... Immunity 1 (7), 533-541, 1994 | 549 | 1994 |
| Lactacystin and clasto-lactacystin β-lactone modify multiple proteasome β-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I … A Craiu, M Gaczynska, T Akopian, CF Gramm, G Fenteany, AL Goldberg, ... Journal of Biological Chemistry 272 (20), 13437-13445, 1997 | 511 | 1997 |
| Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7. M Gaczynska, KL Rock, T Spies, AL Goldberg Proceedings of the National Academy of Sciences 91 (20), 9213-9217, 1994 | 437 | 1994 |
| A proteolytic system that compensates for loss of proteasome function R Glas, M Bogyo, JS McMaster, M Gaczynska, HL Ploegh Nature 392 (6676), 618-622, 1998 | 335 | 1998 |
| Single‐cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT‐related genes in metastatic prostate cancer CL Chen, D Mahalingam, P Osmulski, RR Jadhav, CM Wang, RJ Leach, ... The Prostate 73 (8), 813-826, 2013 | 283 | 2013 |
| Proteasome subunits X and Y alter peptidase activities in opposite ways to the interferon-γ-induced subunits LMP2 and LMP7 M Gaczynska, AL Goldberg, K Tanaka, KB Hendil, KL Rock Journal of biological chemistry 271 (29), 17275-17280, 1996 | 211 | 1996 |
| Proline-and arginine-rich peptides constitute a novel class of allosteric inhibitors of proteasome activity M Gaczynska, PA Osmulski, Y Gao, MJ Post, M Simons Biochemistry 42 (29), 8663-8670, 2003 | 156 | 2003 |
| The central unit within the 19S regulatory particle of the proteasome R Rosenzweig, PA Osmulski, M Gaczynska, MH Glickman Nature structural & molecular biology 15 (6), 573-580, 2008 | 155 | 2008 |
| Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat KA Rodriguez, YH Edrey, P Osmulski, M Gaczynska, R Buffenstein PloS one 7 (5), e35890, 2012 | 129 | 2012 |
| Caretaker or undertaker? The role of the proteasome in aging M Gaczynska, PA Osmulski, WF Ward Mechanisms of ageing and development 122 (3), 235-254, 2001 | 114 | 2001 |
| A tetrahedral transition state at the active sites of the 20S proteasome is coupled to opening of the α-ring channel PA Osmulski, M Hochstrasser, M Gaczynska Structure 17 (8), 1137-1147, 2009 | 109 | 2009 |
| Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease YH Edrey, DX Medina, M Gaczynska, PA Osmulski, S Oddo, A Caccamo, ... Neurobiology of aging 34 (10), 2352-2360, 2013 | 102 | 2013 |
| Role of proteasomes in antigen presentation M Gaczynska, KL Rock, AL Goldberg Enzyme and Protein 47 (4-6), 354-369, 1993 | 99 | 1993 |
| Atomic force microscopy reveals two conformations of the 20 S proteasome from fission yeast PA Osmulski, M Gaczynska Journal of Biological Chemistry 275 (18), 13171-13174, 2000 | 79 | 2000 |
| Nanoenzymology of the 20S proteasome: proteasomal actions are controlled by the allosteric transition PA Osmulski, M Gaczynska Biochemistry 41 (22), 7047-7053, 2002 | 76 | 2002 |
| The growth-suppressive function of the polycomb group protein polyhomeotic is mediated by polymerization of its sterile alpha motif (SAM) domain AK Robinson, BZ Leal, LV Chadwell, R Wang, U Ilangovan, Y Kaur, ... Journal of Biological Chemistry 287 (12), 8702-8713, 2012 | 75 | 2012 |
| AFM of biological complexes: what can we learn? M Gaczynska, PA Osmulski Current opinion in colloid & interface science 13 (5), 351-367, 2008 | 71 | 2008 |
| Small-molecule inhibitors of proteasome activity M Gaczynska, PA Osmulski Ubiquitin-Proteasome Protocols, 1-22, 2005 | 70 | 2005 |
