Principles of bioactive lipid signalling: lessons from sphingolipids YA Hannun, LM Obeid Nature reviews Molecular cell biology 9 (2), 139-150, 2008 | 3574 | 2008 |
Programmed cell death induced by ceramide LM Obeid, CM Linardic, LA Karolak, YA Hannun Science 259 (5102), 1769-1771, 1993 | 2200 | 1993 |
Functions of ceramide in coordinating cellular responses to stress YA Hannun Science 274 (5294), 1855-1859, 1996 | 1988 | 1996 |
The sphingomyelin cycle and the second messenger function of ceramide YA Hannun The Journal of biological chemistry 269 (5), 3125-3128, 1994 | 1627 | 1994 |
Functions of sphingolipids and sphingolipid breakdown products in cellular regulation YA Hannun, RM Bell Science 243 (4890), 500-507, 1989 | 1583 | 1989 |
Biologically active sphingolipids in cancer pathogenesis and treatment B Ogretmen, YA Hannun Nature Reviews Cancer 4 (8), 604-616, 2004 | 1486 | 2004 |
Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. YA Hannun, CR Loomis, AH Merrill Jr, RM Bell Journal of Biological Chemistry 261 (27), 12604-12609, 1986 | 1419 | 1986 |
Sphingolipids and their metabolism in physiology and disease YA Hannun, LM Obeid Nature reviews Molecular cell biology 19 (3), 175-191, 2018 | 1272 | 2018 |
An overview of sphingolipid metabolism: from synthesis to breakdown CR Gault, LM Obeid, YA Hannun Sphingolipids as signaling and regulatory molecules, 1-23, 2010 | 1122 | 2010 |
The ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind YA Hannun, LM Obeid Journal of Biological Chemistry 277 (29), 25847-25850, 2002 | 1099 | 2002 |
Ceramide in the eukaryotic stress response YA Hannun, C Luberto Trends in cell biology 10 (2), 73-80, 2000 | 994 | 2000 |
Ceramide in apoptosis: an overview and current perspectives BJ Pettus, CE Chalfant, YA Hannun Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2002 | 958 | 2002 |
Apoptosis and the dilemma of cancer chemotherapy YA Hannun Blood, The Journal of the American Society of Hematology 89 (6), 1845-1853, 1997 | 945 | 1997 |
The complex life of simple sphingolipids AH Futerman, YA Hannun EMBO reports 5 (8), 777-782, 2004 | 848 | 2004 |
Sphingomyelin turnover induced by vitamin D3 in HL-60 cells: role in cell differentiation T Okazaki, RM Bell, YA Hannun Journal of Biological Chemistry 264 (32), 19076-19080, 1989 | 847 | 1989 |
Bioactive sphingolipids: metabolism and function N Bartke, YA Hannun Journal of lipid research 50, S91-S96, 2009 | 815 | 2009 |
Ceramide activates heterotrimeric protein phosphatase 2A RT Dobrowsky, C Kamibayashi, MC Mumby, YA Hannun Journal of Biological Chemistry 268 (21), 15523-15530, 1993 | 803 | 1993 |
Ceramide: an intracellular signal for apoptosis YA Hannun, LM Obeid Trends in biochemical sciences 20 (2), 73-77, 1995 | 782 | 1995 |
Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation. MY Kim, C Linardic, L Obeid, Y Hannun Journal of Biological Chemistry 266 (1), 484-489, 1991 | 764 | 1991 |
Substantial contribution of extrinsic risk factors to cancer development S Wu, S Powers, W Zhu, YA Hannun Nature 529 (7584), 43-47, 2016 | 754 | 2016 |