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Isabel M Pires
Isabel M Pires
在 manchester.ac.uk 的电子邮件经过验证
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引用次数
引用次数
年份
Regulation of autophagy by ATF4 in response to severe hypoxia
T Rzymski, M Milani, L Pike, F Buffa, HR Mellor, L Winchester, I Pires, ...
Oncogene 29 (31), 4424-4435, 2010
4362010
Anticancer properties of essential oils and other natural products
K Blowman, M Magalhães, MFL Lemos, C Cabral, IM Pires
Evidence‐Based Complementary and Alternative Medicine 2018 (1), 3149362, 2018
2842018
Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment
N Chan, IM Pires, Z Bencokova, C Coackley, KR Luoto, N Bhogal, ...
Cancer research 70 (20), 8045-8054, 2010
2672010
ATM activation and signaling under hypoxic conditions
Z Bencokova, MR Kaufmann, IM Pires, PS Lecane, AJ Giaccia, ...
Molecular and cellular biology, 2009
2602009
Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability
IM Pires, Z Bencokova, M Milani, LK Folkes, JL Li, MR Stratford, AL Harris, ...
Cancer research 70 (3), 925-935, 2010
2262010
Targeting radiation-resistant hypoxic tumour cells through ATR inhibition
IM Pires, MM Olcina, S Anbalagan, JR Pollard, PM Reaper, PA Charlton, ...
British journal of cancer 107 (2), 291-299, 2012
2182012
Replication stress and chromatin context link ATM activation to a role in DNA replication
MM Olcina, IP Foskolou, S Anbalagan, JM Senra, IM Pires, Y Jiang, ...
Molecular cell 52 (5), 758-766, 2013
1252013
RASSF1A–LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2
DE Pefani, R Latusek, I Pires, AM Grawenda, KS Yee, G Hamilton, ...
Nature Cell Biology 16 (10), 962-971, 2014
982014
CH-01 is a hypoxia-activated prodrug that sensitizes cells to hypoxia/reoxygenation through inhibition of Chk1 and Aurora A
C Cazares-Körner, IM Pires, ID Swallow, SC Grayer, LJ O’Connor, ...
ACS chemical biology 8 (7), 1451-1459, 2013
672013
Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy
S Anbalagan, IM Pires, C Blick, MA Hill, DJP Ferguson, DA Chan, ...
Radiotherapy and Oncology 103 (3), 388-393, 2012
562012
Use of the xCELLigence system for real-time analysis of changes in cellular motility and adhesion in physiological conditions
S Scrace, E O’Neill, EM Hammond, IM Pires
Adhesion Protein Protocols, 295-306, 2013
502013
Secondary metabolites (essential oils) from sand-dune plants induce cytotoxic effects in cancer cells
E Beeby, M Magalhães, J Poças, T Collins, MFL Lemos, L Barros, ...
Journal of ethnopharmacology 258, 112803, 2020
452020
Hypoxia-driven cell motility reflects the interplay between JMY and HIF-1α
AS Coutts, IM Pires, L Weston, FM Buffa, M Milani, JL Li, AL Harris, ...
Oncogene 30 (48), 4835-4842, 2011
442011
Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors
IM Pires, TH Ward, C Dive
British journal of pharmacology 159 (6), 1326-1338, 2010
432010
Fission yeast Dss1 associates with the proteasome and is required for efficient ubiquitin-dependent proteolysis
L Jossé, ME Harley, IMS Pires, DA Hughes
Biochemical Journal 393 (1), 303-309, 2006
382006
The role of glucosinolates from cruciferous vegetables (Brassicaceae) in gastrointestinal cancers: from prevention to therapeutics
C Melim, MR Lauro, IM Pires, PJ Oliveira, C Cabral
Pharmaceutics 14 (1), 190, 2022
362022
Evaluation of the first potent and highly selective inhibitor of ATR kinase: an approach to selectively sensitize cancer cells to ionizing radiation and hypoxia
G McKenna, T Brunner, P Charlton, E Fokas, E Hammond, M Mangan, ...
Cancer Research 71 (8_Supplement), 5501-5501, 2011
342011
Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1
IM Pires, Z Bencokova, C McGurk, EM Hammond
Cell cycle 9 (13), 2502-2507, 2010
342010
Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro
T Collins, E Pyne, M Christensen, A Iles, N Pamme, IM Pires
Biomicrofluidics 15 (4), 2021
292021
HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion
IM Pires, NJG Blokland, AWT Broos, FA Poujade, JM Senra, SA Eccles, ...
Cancer biology & therapy 15 (10), 1350-1357, 2014
292014
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