Non-coding variability at the APOE locus contributes to the Alzheimer’s risk X Zhou, Y Chen, KY Mok, TCY Kwok, VCT Mok, Q Guo, FC Ip, Y Chen, ... Nature communications 10 (1), 3310, 2019 | 151 | 2019 |
Gut microbiome alterations precede cerebral amyloidosis and microglial pathology in a mouse model of Alzheimer’s disease Y Chen, L Fang, S Chen, H Zhou, Y Fan, L Lin, J Li, J Xu, Y Chen, Y Ma, ... BioMed research international 2020 (1), 8456596, 2020 | 115 | 2020 |
Myostatin regulates glucose metabolism via the AMP-activated protein kinase pathway in skeletal muscle cells Y Chen, J Ye, L Cao, Y Zhang, W Xia, D Zhu The international journal of biochemistry & cell biology 42 (12), 2072-2081, 2010 | 105 | 2010 |
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis X Zhou, Y Chen, KY Mok, Q Zhao, K Chen, Y Chen, J Hardy, Y Li, AKY Fu, ... Proceedings of the National Academy of Sciences 115 (8), 1697-1706, 2018 | 81 | 2018 |
The atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics Y Xiao, Y Peng, J Wan, G Tang, Y Chen, J Tang, WC Ye, NY Ip, L Shi Journal of Biological Chemistry 288 (27), 20034-20045, 2013 | 79 | 2013 |
Upregulation of myostatin gene expression in streptozotocin-induced type 1 diabetes mice is attenuated by insulin Y Chen, L Cao, J Ye, D Zhu Biochemical and biophysical research communications 388 (1), 112-116, 2009 | 68 | 2009 |
Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice Y Duan, T Ye, Z Qu, Y Chen, A Miranda, X Zhou, KC Lok, Y Chen, AKY Fu, ... Nature Biomedical Engineering 6 (2), 168-180, 2022 | 44 | 2022 |
Coronin 6 regulates acetylcholine receptor clustering through modulating receptor anchorage to actin cytoskeleton Y Chen, FCF Ip, L Shi, Z Zhang, H Tang, YP Ng, WC Ye, AKY Fu, NY Ip Journal of Neuroscience 34 (7), 2413-2421, 2014 | 43 | 2014 |
Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population X Zhou, Y Chen, FCF Ip, NCH Lai, YYT Li, Y Jiang, H Zhong, Y Chen, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 12 (1 …, 2020 | 29 | 2020 |
Spatiotemporal regulation of Rho GTPases in neuronal migration Z Xu, Y Chen, Y Chen Cells 8 (6), 568, 2019 | 29 | 2019 |
Axin regulates dendritic spine morphogenesis through Cdc42-dependent signaling Y Chen, Z Liang, E Fei, Y Chen, X Zhou, W Fang, WY Fu, AKY Fu, NY Ip PloS one 10 (7), e0133115, 2015 | 28 | 2015 |
The association between single-nucleotide polymorphisms of NCF2 and systemic lupus erythematosus in Chinese mainland population B Yu, Y Chen, Q Wu, P Li, Y Shao, J Zhang, Q Zhong, X Peng, H Yang, ... Clinical rheumatology 30, 521-527, 2011 | 28 | 2011 |
Olean-12-Eno[2,3-c] [1,2,5]Oxadiazol-28-Oic Acid (OEOA) Induces G1 Cell Cycle Arrest and Differentiation in Human Leukemia Cell Lines YP Ng, Y Chen, Y Hu, FCF Ip, NY Ip PloS one 8 (5), e63580, 2013 | 21 | 2013 |
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease Y Jiang, X Zhou, HY Wong, L Ouyang, FCF Ip, VMN Chau, SF Lau, W Wu, ... Nature aging 2 (7), 616-634, 2022 | 20 | 2022 |
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction X Zhou, Y Chen, FCF Ip, Y Jiang, H Cao, G Lv, H Zhong, J Chen, T Ye, ... Communications Medicine 3 (1), 49, 2023 | 19 | 2023 |
Muscone with Attenuation of Neuroinflammation and Oxidative Stress Exerts Antidepressant‐Like Effect in Mouse Model of Chronic Restraint Stress H Liu, LL Liu, J Chen, YW Chen, Y Chai, QS Liu, Y Cheng Oxidative Medicine and Cellular Longevity 2022 (1), 3322535, 2022 | 16 | 2022 |
Changes of protein phosphorylation are associated with synaptic functions during the early stage of Alzheimer’s disease Y Chen, J Xu, X Zhou, S Liu, Y Zhang, S Ma, AKY Fu, NY Ip, Y Chen ACS Chemical Neuroscience 10 (9), 3986-3996, 2019 | 15 | 2019 |
Dynamic network modeling of gut microbiota during Alzheimer’s disease progression in mice Y Li, Y Chen, Y Fan, Y Chen, Y Chen Gut Microbes 15 (1), 2172672, 2023 | 14 | 2023 |
Identify the association between polymorphisms of BLK and systemic lupus erythematosus through unlabelled probe‐based high‐resolution melting analysis Y Chen, Q Wu, Y Shao, J Zhang, M Guan, J Wan, B Yu, W Zhang International journal of immunogenetics 39 (4), 321-327, 2012 | 14 | 2012 |
p39-associated Cdk5 activity regulates dendritic morphogenesis L Ouyang, Y Chen, Y Wang, Y Chen, AKY Fu, WY Fu, NY Ip Scientific reports 10 (1), 18746, 2020 | 13 | 2020 |