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Muhammad Ayaz
Muhammad Ayaz
Research Specialist at Moffitt Cancer Center
在 moffitt.org 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Enantiodivergent organocascade reactions
B Westermann, M Ayaz, SS van Berkel
Angewandte Chemie International Edition 5 (49), 846-849, 2010
1292010
GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors
A Kazi, S Xiang, H Yang, D Delitto, J Trevino, RHY Jiang, M Ayaz, ...
Nature communications 9 (1), 5154, 2018
1052018
Synthesis and antibacterial activity of substituted flavones, 4-thioflavones and 4-iminoflavones
EU Mughal, M Ayaz, Z Hussain, A Hasan, A Sadiq, M Riaz, A Malik, ...
Bioorganic & medicinal chemistry 14 (14), 4704-4711, 2006
1032006
Dual farnesyl and geranylgeranyl transferase inhibitor thwarts mutant KRAS-driven patient-derived pancreatic tumors
A Kazi, S Xiang, H Yang, L Chen, P Kennedy, M Ayaz, S Fletcher, ...
Clinical Cancer Research 25 (19), 5984-5996, 2019
652019
Synthesis of tetrazolo-fused benzodiazepines and benzodiazepinones by a two-step protocol using an Ugi-azide reaction for initial diversity generation
S Gunawan, M Ayaz, F De Moliner, B Frett, C Kaiser, N Patrick, Z Xu, ...
Tetrahedron 68 (27-28), 5606-5611, 2012
612012
Structural insights into JAK2 inhibition by ruxolitinib, fedratinib, and derivatives thereof
RR Davis, B Li, SY Yun, A Chan, P Nareddy, S Gunawan, M Ayaz, ...
Journal of medicinal chemistry 64 (4), 2228-2241, 2021
562021
General one-pot, two-step protocol accessing a range of novel polycyclic heterocycles with high skeletal diversity
Z Xu, M Ayaz, AA Cappelli, C Hulme
ACS combinatorial science 14 (8), 460-464, 2012
562012
Potent dual BET bromodomain-kinase inhibitors as value-added multitargeted chemical probes and cancer therapeutics
SW Ember, QT Lambert, N Berndt, S Gunawan, M Ayaz, M Tauro, JY Zhu, ...
Molecular cancer therapeutics 16 (6), 1054-1067, 2017
502017
Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon
AA Akuffo, AY Alontaga, R Metcalf, MS Beatty, A Becker, JM McDaniel, ...
Journal of Biological Chemistry 293 (16), 6187-6200, 2018
432018
Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer
JJ McGuire, JS Frieling, CH Lo, T Li, A Muhammad, HR Lawrence, ...
Nature communications 12 (1), 723, 2021
412021
A novel route to synthesize libraries of quinoxalines via Petasis methodology in two synthetic operations
M Ayaz, J Dietrich, C Hulme
Tetrahedron letters 52 (38), 4821-4823, 2011
392011
Enantiodivergente Organokaskadenreaktionen
B Westermann, M Ayaz, SS van Berkel
Angewandte Chemie 5 (122), 858-861, 2010
392010
Novel succinct routes to quinoxalines and 2-benzimidazolylquinoxalines via the Ugi reaction
M Ayaz, Z Xu, C Hulme
Tetrahedron letters 55 (23), 3406-3409, 2014
382014
Cation–π and π–π stacking interactions allow selective inhibition of butyrylcholinesterase by modified quinine and cinchonidine alkaloids
SA Nawaz, M Ayaz, W Brandt, LA Wessjohann, B Westermann
Biochemical and Biophysical Research Communications 404 (4), 935-940, 2011
372011
Synthesis of diverse nitrogen-enriched heterocyclic scaffolds using a suite of tunable one-pot multicomponent reactions
G Martinez-Ariza, M Ayaz, F Medda, C Hulme
The Journal of Organic Chemistry 79 (11), 5153-5162, 2014
362014
Targeting the BRD4-HOXB13 Co-regulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer
N Nerlakanti, J Yao, DT Nguyen, AK Patel, HR Lawrence, M Ayaz, ...
Molecular cancer therapeutics, molcanther. 0602.2018, 2018
312018
o-Phenylenediacetic Acid Anhydride in the Castagnoli–Cushman Reaction: Extending the Product Space to ε-Lactams
O Bakulina, D Dar’in, M Krasavin
Synlett 28 (10), 1165-1169, 2017
252017
The Synthesis of Stable, Complex Organocesium Tetramic Acids through the Ugi Reaction and Cesium‐Carbonate‐Promoted Cascades
G Martinez‐Ariza, M Ayaz, SA Roberts, WA Rabanal‐León, ...
Angewandte Chemie 127 (40), 11838-11842, 2015
252015
Projected impact of lockdown on SMEs in Pakistan
SA Javed, MU Ayaz
Sustainable Development Policy Institute, 2020
242020
Small molecule medicinal chemistry: strategies and technologies
C Hulme, M Ayaz, G Martinez-Ariza, F Medda, A Shaw, W Czechtizky, ...
:, 145, 2015
232015
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