| Enantiodivergent organocascade reactions B Westermann, M Ayaz, SS van Berkel Angewandte Chemie International Edition 5 (49), 846-849, 2010 | 129 | 2010 |
| GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors A Kazi, S Xiang, H Yang, D Delitto, J Trevino, RHY Jiang, M Ayaz, ... Nature communications 9 (1), 5154, 2018 | 105 | 2018 |
| Synthesis and antibacterial activity of substituted flavones, 4-thioflavones and 4-iminoflavones EU Mughal, M Ayaz, Z Hussain, A Hasan, A Sadiq, M Riaz, A Malik, ... Bioorganic & medicinal chemistry 14 (14), 4704-4711, 2006 | 103 | 2006 |
| Dual farnesyl and geranylgeranyl transferase inhibitor thwarts mutant KRAS-driven patient-derived pancreatic tumors A Kazi, S Xiang, H Yang, L Chen, P Kennedy, M Ayaz, S Fletcher, ... Clinical Cancer Research 25 (19), 5984-5996, 2019 | 65 | 2019 |
| Synthesis of tetrazolo-fused benzodiazepines and benzodiazepinones by a two-step protocol using an Ugi-azide reaction for initial diversity generation S Gunawan, M Ayaz, F De Moliner, B Frett, C Kaiser, N Patrick, Z Xu, ... Tetrahedron 68 (27-28), 5606-5611, 2012 | 61 | 2012 |
| Structural insights into JAK2 inhibition by ruxolitinib, fedratinib, and derivatives thereof RR Davis, B Li, SY Yun, A Chan, P Nareddy, S Gunawan, M Ayaz, ... Journal of medicinal chemistry 64 (4), 2228-2241, 2021 | 56 | 2021 |
| General one-pot, two-step protocol accessing a range of novel polycyclic heterocycles with high skeletal diversity Z Xu, M Ayaz, AA Cappelli, C Hulme ACS combinatorial science 14 (8), 460-464, 2012 | 56 | 2012 |
| Potent dual BET bromodomain-kinase inhibitors as value-added multitargeted chemical probes and cancer therapeutics SW Ember, QT Lambert, N Berndt, S Gunawan, M Ayaz, M Tauro, JY Zhu, ... Molecular cancer therapeutics 16 (6), 1054-1067, 2017 | 50 | 2017 |
| Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon AA Akuffo, AY Alontaga, R Metcalf, MS Beatty, A Becker, JM McDaniel, ... Journal of Biological Chemistry 293 (16), 6187-6200, 2018 | 43 | 2018 |
| Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer JJ McGuire, JS Frieling, CH Lo, T Li, A Muhammad, HR Lawrence, ... Nature communications 12 (1), 723, 2021 | 41 | 2021 |
| A novel route to synthesize libraries of quinoxalines via Petasis methodology in two synthetic operations M Ayaz, J Dietrich, C Hulme Tetrahedron letters 52 (38), 4821-4823, 2011 | 39 | 2011 |
| Enantiodivergente Organokaskadenreaktionen B Westermann, M Ayaz, SS van Berkel Angewandte Chemie 5 (122), 858-861, 2010 | 39 | 2010 |
| Novel succinct routes to quinoxalines and 2-benzimidazolylquinoxalines via the Ugi reaction M Ayaz, Z Xu, C Hulme Tetrahedron letters 55 (23), 3406-3409, 2014 | 38 | 2014 |
| Cation–π and π–π stacking interactions allow selective inhibition of butyrylcholinesterase by modified quinine and cinchonidine alkaloids SA Nawaz, M Ayaz, W Brandt, LA Wessjohann, B Westermann Biochemical and Biophysical Research Communications 404 (4), 935-940, 2011 | 37 | 2011 |
| Synthesis of diverse nitrogen-enriched heterocyclic scaffolds using a suite of tunable one-pot multicomponent reactions G Martinez-Ariza, M Ayaz, F Medda, C Hulme The Journal of Organic Chemistry 79 (11), 5153-5162, 2014 | 36 | 2014 |
| Targeting the BRD4-HOXB13 Co-regulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer N Nerlakanti, J Yao, DT Nguyen, AK Patel, HR Lawrence, M Ayaz, ... Molecular cancer therapeutics, molcanther. 0602.2018, 2018 | 31 | 2018 |
| o-Phenylenediacetic Acid Anhydride in the Castagnoli–Cushman Reaction: Extending the Product Space to ε-Lactams O Bakulina, D Dar’in, M Krasavin Synlett 28 (10), 1165-1169, 2017 | 25 | 2017 |
| The Synthesis of Stable, Complex Organocesium Tetramic Acids through the Ugi Reaction and Cesium‐Carbonate‐Promoted Cascades G Martinez‐Ariza, M Ayaz, SA Roberts, WA Rabanal‐León, ... Angewandte Chemie 127 (40), 11838-11842, 2015 | 25 | 2015 |
| Projected impact of lockdown on SMEs in Pakistan SA Javed, MU Ayaz Sustainable Development Policy Institute, 2020 | 24 | 2020 |
| Small molecule medicinal chemistry: strategies and technologies C Hulme, M Ayaz, G Martinez-Ariza, F Medda, A Shaw, W Czechtizky, ... :, 145, 2015 | 23 | 2015 |
