Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs IG Winkler, NA Sims, AR Pettit, V Barbier, B Nowlan, F Helwani, IJ Poulton, ... Blood, The Journal of the American Society of Hematology 116 (23), 4815-4828, 2010 | 938 | 2010 |
Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit NA Sims, TJ Martin BoneKEy reports 3, 2014 | 870 | 2014 |
Osteoclast-derived activity in the coupling of bone formation to resorption TJ Martin, NA Sims Trends in molecular medicine 11 (2), 76-81, 2005 | 829 | 2005 |
Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption NA Sims, JH Gooi Seminars in cell & developmental biology 19 (5), 444-451, 2008 | 692 | 2008 |
Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment CR Walkley, JM Shea, NA Sims, LE Purton, SH Orkin Cell 129 (6), 1081-1095, 2007 | 475 | 2007 |
Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone LM Calvi, NA Sims, JL Hunzelman, MC Knight, A Giovannetti, JM Saxton, ... The Journal of clinical investigation 107 (3), 277-286, 2001 | 426 | 2001 |
Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-β in bone remodeling in females but not in males NA Sims, S Dupont, A Krust, P Clement-Lacroix, D Minet, ... Bone 30 (1), 18-25, 2002 | 419 | 2002 |
The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo LS Whyte, E Ryberg, NA Sims, SA Ridge, K Mackie, PJ Greasley, ... Proceedings of the national Academy of sciences 106 (38), 16511-16516, 2009 | 400 | 2009 |
Overexpression of ΔFosB transcription factor (s) increases bone formation and inhibits adipogenesis G Sabatakos, NA Sims, J Chen, K Aoki, MB Kelz, M Amling, Y Bouali, ... Nature medicine 6 (9), 985-990, 2000 | 397 | 2000 |
Model structure and control of bone remodeling: a theoretical study P Pivonka, J Zimak, DW Smith, BS Gardiner, CR Dunstan, NA Sims, ... Bone 43 (2), 249-263, 2008 | 358 | 2008 |
Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice M Kansara, M Tsang, L Kodjabachian, NA Sims, MK Trivett, M Ehrich, ... The Journal of clinical investigation 119 (4), 837-851, 2009 | 336 | 2009 |
Decreased c-Src expression enhances osteoblast differentiation and bone formation M Marzia, NA Sims, S Voit, S Migliaccio, A Taranta, S Bernardini, ... The Journal of cell biology 151 (2), 311-320, 2000 | 332 | 2000 |
Interleukin‐6 modulates production of T lymphocyte–derived cytokines in antigen‐induced arthritis and drives inflammation‐induced osteoclastogenesis PKK Wong, JMW Quinn, NA Sims, A van Nieuwenhuijze, IK Campbell, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2006 | 327 | 2006 |
Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis E Romas, NA Sims, DK Hards, M Lindsay, JWM Quinn, PFJ Ryan, ... The American journal of pathology 161 (4), 1419-1427, 2002 | 326 | 2002 |
Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice EC Walker, NE McGregor, IJ Poulton, M Solano, S Pompolo, ... The Journal of clinical investigation 120 (2), 582-592, 2010 | 310 | 2010 |
Quantifying the osteocyte network in the human skeleton PR Buenzli, NA Sims Bone 75, 144-150, 2015 | 308 | 2015 |
Bone homeostasis in growth hormone receptor–null mice is restored by IGF-I but independent of Stat5 NA Sims, P Clément-Lacroix, F Da Ponte, Y Bouali, N Binart, R Moriggl, ... The Journal of clinical investigation 106 (9), 1095-1103, 2000 | 276 | 2000 |
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma DM Thomas, SA Johnson, NA Sims, MK Trivett, JL Slavin, BP Rubin, ... The Journal of cell biology 167 (5), 925-934, 2004 | 254 | 2004 |
SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1–dependent inflammatory arthritis PKK Wong, PJ Egan, BA Croker, K O’Donnell, NA Sims, S Drake, H Kiu, ... The Journal of clinical investigation 116 (6), 1571-1581, 2006 | 247 | 2006 |
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2−/− mice H Gil-Henn, O Destaing, NA Sims, K Aoki, N Alles, L Neff, A Sanjay, ... The Journal of cell biology 178 (6), 1053-1064, 2007 | 244 | 2007 |