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Jose I. Aguirre
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Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss
JI Aguirre, LI Plotkin, SA Stewart, RS Weinstein, AM Parfitt, SC Manolagas, ...
Journal of bone and mineral research 21 (4), 605-615, 2006
6532006
Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs
LI Plotkin, I Mathov, JI Aguirre, AM Parfitt, SC Manolagas, T Bellido
American Journal of Physiology-Cell Physiology 289 (3), C633-C643, 2005
3292005
Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation
LI Plotkin, JI Aguirre, S Kousteni, SC Manolagas, T Bellido
Journal of Biological Chemistry 280 (8), 7317-7325, 2005
3182005
Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and …
J Aguirre, L Buttery, M O’Shaughnessy, F Afzal, IF de Marticorena, ...
The American journal of pathology 158 (1), 247-257, 2001
2822001
Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens
JR Chen, LI Plotkin, JI Aguirre, L Han, RL Jilka, S Kousteni, T Bellido, ...
Journal of biological chemistry 280 (6), 4632-4638, 2005
2172005
Oncologic doses of zoledronic acid induce osteonecrosis of the jaw‐like lesions in rice rats (Oryzomys palustris) with periodontitis
JI Aguirre, MP Akhter, DB Kimmel, JE Pingel, A Williams, M Jorgensen, ...
Journal of Bone and Mineral Research 27 (10), 2130-2143, 2012
1722012
A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction
JI Aguirre, LI Plotkin, AR Gortazar, MM Millan, CA O'Brien, SC Manolagas, ...
Journal of Biological Chemistry 282 (35), 25501-25508, 2007
1722007
Effects of alendronate on bone healing after tooth extraction in rats
JI Aguirre, MK Altman, SM Vanegas, SE Franz, ACF Bassit, TJ Wronski
Oral diseases 16 (7), 674-685, 2010
1182010
Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats
S Taylor, MS Ominsky, R Hu, E Pacheco, YD He, DL Brown, JI Aguirre, ...
Bone 84, 148-159, 2016
972016
Differential temporal effects of sclerostin antibody and parathyroid hormone on cancellous and cortical bone and quantitative differences in effects on the osteoblast lineage …
MS Ominsky, DL Brown, G Van, D Cordover, E Pacheco, E Frazier, ...
Bone 81, 380-391, 2015
852015
Vascular remodeling and ET-1 expression in rat strains with different responses to chronic hypoxia
JI Aguirre, NW Morrell, L Long, P Clift, PD Upton, JM Polak, MR Wilkins
American Journal of Physiology-Lung Cellular and Molecular Physiology 278 (5 …, 2000
752000
Role for β1 integrins in cortical osteocytes during acute musculoskeletal disuse
JA Phillips, EAC Almeida, EL Hill, JI Aguirre, MF Rivera, I Nachbandi, ...
Matrix Biology 27 (7), 609-618, 2008
642008
Sclerostin inhibition prevents spinal cord injury‐induced cancellous bone loss
LA Beggs, F Ye, P Ghosh, DT Beck, CF Conover, A Balaez, JR Miller, ...
Journal of Bone and Mineral Research 30 (4), 681-689, 2015
622015
Testosterone dose dependently prevents bone and muscle loss in rodents after spinal cord injury
JF Yarrow, CF Conover, LA Beggs, DT Beck, DM Otzel, A Balaez, ...
Journal of neurotrauma 31 (9), 834-845, 2014
602014
Exosomes: novel regulators of bone remodelling and potential therapeutic agents for orthodontics
LS Holliday, KP McHugh, J Zuo, JI Aguirre, JK Neubert, WJ Rody Jr
Orthodontics & craniofacial research 20, 95-99, 2017
572017
Ectopic expression of Wnt10b decreases adiposity and improves glucose homeostasis in obese rats
G Aslanidi, V Kroutov, G Philipsberg, K Lamb, M Campbell-Thompson, ...
American Journal of Physiology-Endocrinology and Metabolism 293 (3), E726-E736, 2007
532007
Preclinical models of medication-related osteonecrosis of the jaw (MRONJ)
JI Aguirre, EJ Castillo, DB Kimmel
Bone 153, 116184, 2021
522021
Antibiotic perturbation of gut microbiota dysregulates osteoimmune cross talk in postpubertal skeletal development
JD Hathaway-Schrader, HM Steinkamp, MB Chavez, NA Poulides, ...
The American journal of pathology 189 (2), 370-390, 2019
492019
Teriparatide [rhPTH (1-34)], but not strontium ranelate, demonstrated bone anabolic efficacy in mature, osteopenic, ovariectomized rats
YL Ma, QQ Zeng, LL Porras, A Harvey, TL Moore, TL Shelbourn, ...
Endocrinology 152 (5), 1767-1778, 2011
432011
Enhanced alveolar bone loss in a model of non‐invasive periodontitis in rice rats
JI Aguirre, MP Akhter, DB Kimmel, J Pingel, X Xia, A Williams, ...
Oral diseases 18 (5), 459-468, 2012
422012
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