| Masking the 5′ terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex ES Machlin, P Sarnow, SM Sagan Proceedings of the National Academy of Sciences 108 (8), 3193-3198, 2011 | 365 | 2011 |
| Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection SH Safiabadi Tali, JJ LeBlanc, Z Sadiq, OD Oyewunmi, C Camargo, ... Clinical microbiology reviews 34 (3), 10.1128/cmr. 00228-20, 2021 | 360 | 2021 |
| Analysis of the T cell response to Zika virus and identification of a novel CD8+ T cell epitope in immunocompetent mice RD Pardy, MM Rajah, SA Condotta, NG Taylor, SM Sagan, MJ Richer PLoS pathogens 13 (2), e1006184, 2017 | 143 | 2017 |
| Bioinformatic and physical characterizations of genome-scale ordered RNA structure in mammalian RNA viruses M Davis, SM Sagan, JP Pezacki, DJ Evans, P Simmonds Journal of virology 82 (23), 11824-11836, 2008 | 117 | 2008 |
| The diverse roles of microRNAs at the Host–Virus Interface A Bernier, SM Sagan Viruses 10 (8), 440, 2018 | 99 | 2018 |
| The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication SM Sagan, Y Rouleau, C Leggiadro, L Supekova, PG Schultz, AI Su, ... Biochemistry and cell biology 84 (1), 67-79, 2006 | 99 | 2006 |
| Peroxisome proliferator-activated receptor α antagonism inhibits hepatitis C virus replication B Rakic, SM Sagan, M Noestheden, S Bélanger, X Nan, CL Evans, XS Xie, ... Chemistry & biology 13 (1), 23-30, 2006 | 98 | 2006 |
| Dissecting noncoding and pathogen RNA–protein interactomes RA Flynn, L Martin, RC Spitale, BT Do, SM Sagan, B Zarnegar, K Qu, ... RNA 21 (1), 135-143, 2015 | 92 | 2015 |
| Molecular determinants of flavivirus virion assembly TR Barnard, QH Abram, QF Lin, AB Wang, SM Sagan Trends in Biochemical Sciences 46 (5), 378-390, 2021 | 76 | 2021 |
| Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism RK Lyn, DC Kennedy, SM Sagan, DR Blais, Y Rouleau, AF Pegoraro, ... Virology 394 (1), 130-142, 2009 | 76 | 2009 |
| The miR-17∼ 92 microRNA Cluster Is a Global Regulator of Tumor Metabolism S Izreig, B Samborska, RM Johnson, A Sergushichev, EH Ma, C Lussier, ... Cell Reports 16 (7), 1915-1928, 2016 | 71 | 2016 |
| miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5′ end from the cellular pyrophosphatases, DOM3Z and DUSP11 Y Amador-Cañizares, A Bernier, JA Wilson, SM Sagan Nucleic acids research 46 (10), 5139-5158, 2018 | 65 | 2018 |
| miR-122 and Ago interactions with the HCV genome alter the structure of the viral 5′ terminus J Chahal, LFR Gebert, HH Gan, E Camacho, KC Gunsalus, IJ MacRae, ... Nucleic acids research 47 (10), 5307-5324, 2019 | 60 | 2019 |
| Unraveling the mysterious interactions between hepatitis C virus RNA and liver-specific microRNA-122 P Sarnow, SM Sagan Annual review of virology 3 (1), 309-332, 2016 | 59 | 2016 |
| Cis-acting RNA elements in the Hepatitis C virus RNA genome SM Sagan, J Chahal, P Sarnow Virus research, 2015 | 49 | 2015 |
| Hepatitis C virus and human miR-122: insights from the bench to the clinic JA Wilson, SM Sagan Current opinion in virology 7, 11-18, 2014 | 46 | 2014 |
| Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus JP Pezacki, SM Sagan, AM Tonary, Y Rouleau, S Bélanger, L Supekova, ... BMC chemical biology 9 (1), 1-15, 2009 | 39 | 2009 |
| Neuronal microRNA regulation in experimental autoimmune encephalomyelitis CA Juźwik, S Drake, MA Lécuyer, RM Johnson, B Morquette, Y Zhang, ... Scientific reports 8 (1), 13437, 2018 | 36 | 2018 |
| Effects of pH and salt concentration on the siRNA binding activity of the RNA silencing suppressor protein p19 R Koukiekolo, SM Sagan, JP Pezacki FEBS letters 581 (16), 3051-3056, 2007 | 34 | 2007 |
| Zika virus: emergence, phylogenetics, challenges, and opportunities MM Rajah, RD Pardy, SA Condotta, MJ Richer, SM Sagan ACS infectious diseases 2 (11), 763-772, 2016 | 32 | 2016 |
