Paclitaxel reduces tumor growth by reprogramming tumor-associated macrophages to an M1 profile in a TLR4-dependent manner CW Wanderley, DF Colon, JPM Luiz, FF Oliveira, PR Viacava, CA Leite, ... Cancer research 78 (20), 5891-5900, 2018 | 355 | 2018 |
The antioxidant effects of the flavonoids rutin and quercetin inhibit oxaliplatin-induced chronic painful peripheral neuropathy MI Azevedo, AF Pereira, RB Nogueira, FE Rolim, GAC Brito, DVT Wong, ... Molecular pain 9, 1744-8069-9-53, 2013 | 289 | 2013 |
Phosphoinositide 3-kinase gamma inhibition protects from anthracycline cardiotoxicity and reduces tumor growth M Li, V Sala, MC De Santis, J Cimino, P Cappello, N Pianca, A Di Bona, ... Circulation 138 (7), 696-711, 2018 | 170 | 2018 |
Irinotecan-and 5-fluorouracil-induced intestinal mucositis: insights into pathogenesis and therapeutic perspectives RA Ribeiro, CWS Wanderley, DVT Wong, JMSC Mota, CAVG Leite, ... Cancer chemotherapy and pharmacology 78, 881-893, 2016 | 152 | 2016 |
Hydrogen sulfide prevents ethanol-induced gastric damage in mice: role of ATP-sensitive potassium channels and capsaicin-sensitive primary afferent neurons JVR Medeiros, VH Bezerra, AS Gomes, ALR Barbosa, RCP Lima-Junior, ... Journal of Pharmacology and Experimental Therapeutics 330 (3), 764-770, 2009 | 110 | 2009 |
Role of inducible nitric oxide synthase pathway on methotrexate-induced intestinal mucositis in rodents RFC Leitão, GAC Brito, RB Oriá, MB Braga-Neto, EAL Bellaguarda, ... BMC gastroenterology 11, 1-10, 2011 | 94 | 2011 |
Pentacyclic triterpenoids, α, β-amyrins, suppress the scratching behavior in a mouse model of pruritus FA Oliveira, RCP Lima-Junior, WM Cordeiro, GM Vieira-Júnior, ... Pharmacology Biochemistry and Behavior 78 (4), 719-725, 2004 | 94 | 2004 |
IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice R Guabiraba, AG Besnard, GB Menezes, T Secher, MS Jabir, SS Amaral, ... Mucosal immunology 7 (5), 1079-1093, 2014 | 91 | 2014 |
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis CC Campa, RL Silva, JP Margaria, T Pirali, MS Mattos, LR Kraemer, ... Nature communications 9 (1), 5232, 2018 | 87 | 2018 |
Effect of different doses of zoledronic acid in establishing of bisphosphonate-related osteonecrosis PG de Barros Silva, AECF Junior, CR Teófilo, MC Barbosa, RCPL Júnior, ... Archives of oral biology 60 (9), 1237-1245, 2015 | 84 | 2015 |
Involvement of nitric oxide on the pathogenesis of irinotecan-induced intestinal mucositis: role of cytokines on inducible nitric oxide synthase activation RCP Lima-Júnior, AA Figueiredo, HC Freitas, MLP Melo, DVT Wong, ... Cancer chemotherapy and pharmacology 69, 931-942, 2012 | 80 | 2012 |
5-fluorouracil induces enteric neuron death and glial activation during intestinal mucositis via a S100B-RAGE-NFκB-dependent pathway DVS Costa, AC Bon-Frauches, AMHP Silva, RCP Lima-Júnior, CS Martins, ... Scientific reports 9 (1), 665, 2019 | 74 | 2019 |
Oleanolic acid, a pentacyclic triterpene attenuates capsaicin-induced nociception in mice: possible mechanisms JL Maia, RCP Lima-Júnior, CM Melo, JP David, JM David, AR Campos, ... Pharmacological Research 54 (4), 282-286, 2006 | 72 | 2006 |
Oleanolic acid, a pentacyclic triterpene attenuates the mustard oil-induced colonic nociception in mice JL Maia, RCP Lima-Júnior, JP David, JM David, FA Santos, VS Rao Biological and Pharmaceutical Bulletin 29 (1), 82-85, 2006 | 69 | 2006 |
The adaptor protein Myd88 is a key signaling molecule in the pathogenesis of irinotecan-induced intestinal mucositis DVT Wong, RCP Lima-Júnior, CBM Carvalho, VF Borges, ... PloS one 10 (10), e0139985, 2015 | 64 | 2015 |
α-Phellandrene, a cyclic monoterpene, attenuates inflammatory response through neutrophil migration inhibition and mast cell degranulation HDAS Siqueira, BS Neto, DP Sousa, BS Gomes, FV da Silva, FVM Cunha, ... Life sciences 160, 27-33, 2016 | 60 | 2016 |
Bothrops jararacussu snake venom-induces a local inflammatory response in a prostanoid-and neutrophil-dependent manner CWS Wanderley, CMS Silva, DVT Wong, RM Ximenes, DFC Morelo, ... Toxicon 90, 134-147, 2014 | 58 | 2014 |
Anti-inflammatory effect of the monoterpene myrtenol is dependent on the direct modulation of neutrophil migration and oxidative stress BS Gomes, BPS Neto, EM Lopes, FVM Cunha, AR Araújo, ... Chemico-Biological Interactions 273, 73-81, 2017 | 57 | 2017 |
Targeted inhibition of IL‐18 attenuates irinotecan‐induced intestinal mucositis in mice RCP Lima‐Júnior, HC Freitas, DVT Wong, CWS Wanderley, LG Nunes, ... British journal of pharmacology 171 (9), 2335-2350, 2014 | 57 | 2014 |
Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice PMG Soares, RCP Lima-Junior, JMSC Mota, PFC Justino, GAC Brito, ... Cancer chemotherapy and pharmacology 68, 713-720, 2011 | 55 | 2011 |