IDH1 and IDH2 Mutations in Gliomas AL Cohen, SL Holmen, H Colman Current neurology and neuroscience reports 13, 1-7, 2013 | 746 | 2013 |
Essential role of β-catenin in postnatal bone acquisition SL Holmen, CR Zylstra, A Mukherjee, RE Sigler, MC Faugere, ... Journal of Biological Chemistry 280 (22), 21162-21168, 2005 | 715 | 2005 |
Decreased BMD and Limb Deformities in Mice Carrying Mutations in Both Lrp5 and Lrp6 SL Holmen, TA Giambernardi, CR Zylstra, BD BucknerBerghuis, ... Journal of Bone and Mineral Research 19 (12), 2033-2040, 2004 | 410 | 2004 |
Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling M Ai, SL Holmen, W Van Hul, BO Williams, ML Warman Molecular and cellular biology 25 (12), 4946-4955, 2005 | 297 | 2005 |
Molecular profiling reveals unique immune and metabolic features of melanoma brain metastases GM Fischer, A Jalali, DA Kircher, WC Lee, JL McQuade, LE Haydu, ... Cancer discovery 9 (5), 628-645, 2019 | 271 | 2019 |
Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma Y Yu, K Schleich, B Yue, S Ji, P Lohneis, K Kemper, MR Silvis, N Qutob, ... Cancer cell 33 (2), 322-336. e8, 2018 | 154 | 2018 |
AKT1 activation promotes development of melanoma metastases JH Cho, JP Robinson, RA Arave, WJ Burnett, DA Kircher, G Chen, ... Cell reports 13 (5), 898-905, 2015 | 148 | 2015 |
Chemical analysis of constitutive pigmentation of human epidermis reveals constant eumelanin to pheomelanin ratio S Del Bino, S Ito, J Sok, Y Nakanishi, P Bastien, K Wakamatsu, F Bernerd Pigment cell & melanoma research 28 (6), 707-717, 2015 | 134 | 2015 |
A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate β-catenin-dependent signaling SL Holmen, A Salic, CR Zylstra, MW Kirschner, BO Williams Journal of Biological Chemistry 277 (38), 34727-34735, 2002 | 132 | 2002 |
Melanoma models for the next generation of therapies EE Patton, KL Mueller, DJ Adams, N Anandasabapathy, AE Aplin, ... Cancer cell 39 (5), 610-631, 2021 | 128 | 2021 |
Melanoma central nervous system metastases: current approaches, challenges, and opportunities JV Cohen, H Tawbi, KA Margolin, R Amravadi, M Bosenberg, ... Pigment cell & melanoma research 29 (6), 627-642, 2016 | 128 | 2016 |
Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation JP Robinson, MW VanBrocklin, AR Guilbeault, DL Signorelli, S Brandner, ... Oncogene 29 (3), 335-344, 2010 | 112 | 2010 |
Exploiting drug addiction mechanisms to select against MAPKi-resistant melanoma A Hong, G Moriceau, L Sun, S Lomeli, M Piva, R Damoiseaux, SL Holmen, ... Cancer discovery 8 (1), 74-93, 2018 | 111 | 2018 |
Essential role for Ras signaling in glioblastoma maintenance SL Holmen, BO Williams Cancer research 65 (18), 8250-8255, 2005 | 111 | 2005 |
Potent selection of antigen loss variants of B16 melanoma following inflammatory killing of melanocytes in vivo L Sanchez-Perez, T Kottke, RM Diaz, A Ahmed, J Thompson, H Chong, ... Cancer research 65 (5), 2009-2017, 2005 | 105 | 2005 |
Mutant IDH1 promotes glioma formation in vivo B Philip, XY Diana, MR Silvis, CH Shin, JP Robinson, GL Robinson, ... Cell reports 23 (5), 1553-1564, 2018 | 104 | 2018 |
Mitogen-activated protein kinase inhibition induces translocation of Bmf to promote apoptosis in melanoma MW VanBrocklin, M Verhaegen, MS Soengas, SL Holmen Cancer research 69 (5), 1985-1994, 2009 | 88 | 2009 |
Differential oncogenic potential of activated RAS isoforms in melanocytes T Whitwam, MW Vanbrocklin, ME Russo, PT Haak, D Bilgili, JH Resau, ... Oncogene 26 (31), 4563-4570, 2007 | 87 | 2007 |
APC inhibits ERK pathway activation and cellular proliferation induced by RAS KS Park, SH Jeon, SE Kim, YY Bahk, SL Holmen, BO Williams, KC Chung, ... Journal of cell science 119 (5), 819-827, 2006 | 81 | 2006 |
Efficient lipid-mediated transfection of DNA into primary rat hepatocytes SL Holmen, MW Vanbrocklin, RR Eversole, SR Stapleton, LC Ginsberg In Vitro Cellular & Developmental Biology-Animal 31, 347-351, 1995 | 79 | 1995 |