| Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease C Venegas, S Kumar, BS Franklin, T Dierkes, R Brinkschulte, D Tejera, ... Nature 552 (7685), 355-361, 2017 | 845 | 2017 |
| Structure–function relationships in HIV‐1 Nef M Geyer, OT Fackler, BM Peterlin EMBO reports, 2001 | 503 | 2001 |
| The RNA polymerase II carboxy-terminal domain (CTD) code D Eick, M Geyer Chemical reviews 113 (11), 8456-8490, 2013 | 478 | 2013 |
| Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape PA Koenig, H Das, H Liu, BM Kümmerer, FN Gohr, LM Jenster, ... Science 371 (6530), eabe6230, 2021 | 348 | 2021 |
| Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins T Schweins, M Geyer, K Scheffzek, A Warshel, HR Kalbitzer, ... Nature structural biology 2 (1), 36-44, 1995 | 333 | 1995 |
| Formins as effector proteins of Rho GTPases S Kühn, M Geyer Small GTPases 5 (3), e983876, 2014 | 328 | 2014 |
| NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain A Stutz, CC Kolbe, R Stahl, GL Horvath, BS Franklin, O van Ray, ... Journal of Experimental Medicine 214 (6), 1725-1736, 2017 | 325 | 2017 |
| Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors T Zhang, N Kwiatkowski, CM Olson, SE Dixon-Clarke, BJ Abraham, ... Nature chemical biology 12 (10), 876-884, 2016 | 321 | 2016 |
| The control of HIV transcription: keeping RNA polymerase II on track M Ott, M Geyer, Q Zhou Cell host & microbe 10 (5), 426-435, 2011 | 321 | 2011 |
| Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions OT Fackler, W Luo, M Geyer, AS Alberts, BM Peterlin Molecular cell 3 (6), 729-739, 1999 | 318 | 1999 |
| Fifteen formins for an actin filament: a molecular view on the regulation of human formins A Schönichen, M Geyer Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1803 (2), 152-163, 2010 | 300 | 2010 |
| Conformational Transitions in p21ras and in Its Complexes with the Effector Protein Raf-RBD and the GTPase Activating Protein GAP M Geyer, T Schweins, C Herrmann, T Prisner, A Wittinghofer, HR Kalbitzer Biochemistry 35 (32), 10308-10320, 1996 | 280 | 1996 |
| CDK12 inhibition reverses de novo and acquired PARP inhibitor resistance in BRCA wild-type and mutated models of triple-negative breast cancer SF Johnson, C Cruz, AK Greifenberg, S Dust, DG Stover, D Chi, ... Cell reports 17 (9), 2367-2381, 2016 | 276 | 2016 |
| GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins M Geyer, A Wittinghofer Current opinion in structural biology 7 (6), 786-792, 1997 | 276 | 1997 |
| Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation F Itzen, AK Greifenberg, CA Bösken, M Geyer Nucleic acids research 42 (12), 7577-7590, 2014 | 261 | 2014 |
| Rational discovery of molecular glue degraders via scalable chemical profiling C Mayor-Ruiz, S Bauer, M Brand, Z Kozicka, M Siklos, H Imrichova, ... Nature chemical biology 16 (11), 1199-1207, 2020 | 245 | 2020 |
| FMNL2 drives actin-based protrusion and migration downstream of Cdc42 J Block, D Breitsprecher, S Kühn, M Winterhoff, F Kage, R Geffers, ... Current Biology 22 (11), 1005-1012, 2012 | 233 | 2012 |
| Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription M Barboric, JHN Yik, N Czudnochowski, Z Yang, R Chen, X Contreras, ... Nucleic acids research 35 (6), 2003-2012, 2007 | 212 | 2007 |
| CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation M Krajewska, R Dries, AV Grassetti, S Dust, Y Gao, H Huang, B Sharma, ... Nature communications 10 (1), 1757, 2019 | 210 | 2019 |
| Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition N Czudnochowski, CA Bösken, M Geyer Nature communications 3 (1), 842, 2012 | 210 | 2012 |
