Crystal structure and mechanism of a bacterial fluorinating enzyme C Dong, F Huang, H Deng, C Schaffrath, JB Spencer, D O'hagan, ... Nature 427 (6974), 561-565, 2004 | 383 | 2004 |
Enzymatic Fluorination and Biotechnological Developments of the Fluorinase D O'Hagan, H Deng Chemical Reviews 115 (2), 634-649, 2014 | 315 | 2014 |
Diverse metabolic profiles of a Streptomyces strain isolated from a hyper-arid environment ME Rateb, WE Houssen, WTA Harrison, H Deng, CK Okoro, JA Asenjo, ... Journal of natural products 74 (9), 1965-1971, 2011 | 200 | 2011 |
Upconversion NIR-II fluorophores for mitochondria-targeted cancer imaging and photothermal therapy H Zhou, X Zeng, A Li, W Zhou, L Tang, W Hu, Q Fan, X Meng, H Deng, ... Nature Communications 11 (1), 6183, 2020 | 197 | 2020 |
Chaxamycins A–D, Bioactive Ansamycins from a Hyper-arid Desert Streptomyces sp. ME Rateb, WE Houssen, M Arnold, MH Abdelrahman, H Deng, ... Journal of natural products 74 (6), 1491-1499, 2011 | 150 | 2011 |
Novel NIR-II organic fluorophores for bioimaging beyond 1550 nm Y Li, Y Liu, Q Li, X Zeng, T Tian, W Zhou, Y Cui, X Wang, X Cheng, Q Ding, ... Chemical Science 11 (10), 2621-2626, 2020 | 147 | 2020 |
Fluorometabolite biosynthesis and the fluorinase from Streptomyces cattleya H Deng, D O'Hagan, C Schaffrath Natural product reports 21 (6), 773-784, 2004 | 138 | 2004 |
Identification of Fluorinases from Streptomyces sp MA37, Norcardia brasiliensis, and Actinoplanes sp N902‐109 by Genome Mining H Deng, L Ma, N Bandaranayaka, Z Qin, G Mann, K Kyeremeh, Y Yu, ... ChemBioChem 15 (3), 364-368, 2014 | 128 | 2014 |
The fluorinase from Streptomyces cattleya is also a chlorinase H Deng, SL Cobb, AR McEwan, RP McGlinchey, JH Naismith, D O’Hagan, ... Angewandte Chemie (International ed. in English) 45 (5), 759, 2006 | 114 | 2006 |
Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert SS Elsayed, F Trusch, H Deng, A Raab, I Prokes, K Busarakam, ... The Journal of organic chemistry 80 (20), 10252-10260, 2015 | 110 | 2015 |
Isolation and characterisation of 5′-fluorodeoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya C Schaffrath, H Deng, D O’Hagan FEBS letters 547 (1-3), 111-114, 2003 | 98 | 2003 |
Enzymatic fluorination in Streptomyces cattleya takes place with an inversion of configuration consistent with an SN2 reaction mechanism CD Cadicamo, J Courtieu, H Deng, A Meddour, D O'Hagan ChemBioChem 5 (5), 685-690, 2004 | 85 | 2004 |
The first enzymatic method for C–18F bond formation: the synthesis of 5′‐[18F]‐fluoro‐5′‐deoxyadenosine for imaging with PET L Martarello, C Schaffrath, H Deng, AD Gee, A Lockhart, D O'Hagan Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal …, 2003 | 75 | 2003 |
Fluorinase mediated C–18 F bond formation, an enzymatic tool for PET labelling H Deng, SL Cobb, AD Gee, A Lockhart, L Martarello, RP McGlinchey, ... Chemical communications, 652-654, 2006 | 73 | 2006 |
The fluorinase, the chlorinase and the duf-62 enzymes H Deng, D O’Hagan Current opinion in chemical biology 12 (5), 582-592, 2008 | 72 | 2008 |
Identification of a fluorometabolite from Streptomyces sp. MA37:(2 R 3 S 4 S)-5-fluoro-2, 3, 4-trihydroxypentanoic acid L Ma, A Bartholome, MH Tong, Z Qin, Y Yu, T Shepherd, K Kyeremeh, ... Chemical science 6 (2), 1414-1419, 2015 | 67 | 2015 |
Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674 S Huang, L Ma, MH Tong, Y Yu, D O'Hagan, H Deng Organic & Biomolecular Chemistry, 2014 | 65 | 2014 |
Dithiolopyrrolone natural products: isolation, synthesis and biosynthesis Z Qin, S Huang, Y Yu, H Deng Marine drugs 11 (10), 3970-3997, 2013 | 61 | 2013 |
Fluorine speciation analysis using reverse phase liquid chromatography coupled off-line to continuum source molecular absorption spectrometry (CS-MAS): identification and … Z Qin, D McNee, H Gleisner, A Raab, K Kyeremeh, M Jaspars, E Krupp, ... Analytical chemistry 84 (14), 6213-6219, 2012 | 59 | 2012 |
An enzymatic route to 5-deoxy-5-[18F] fluoro-d-ribose, a [18 F]-fluorinated sugar for PET imaging M Onega, J Domarkas, H Deng, LF Schweiger, TAD Smith, AE Welch, ... Chemical Communications 46 (1), 139-141, 2010 | 57 | 2010 |