Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized, controlled trials MJ Sorich, MD Wiese, A Rowland, G Kichenadasse, RA McKinnon, ... Annals of Oncology 26 (1), 13-21, 2015 | 608 | 2015 |
Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer DW NEBERT, RA MCKINNON, A Puga DNA and cell biology 15 (4), 273-280, 1996 | 452 | 1996 |
Meta-analysis of BRAF mutation as a predictive biomarker of benefit from anti-EGFR monoclonal antibody therapy for RAS wild-type metastatic colorectal cancer A Rowland, MM Dias, MD Wiese, G Kichenadasse, RA McKinnon, ... British journal of cancer 112 (12), 1888-1894, 2015 | 381 | 2015 |
The UDP-glycosyltransferase (UGT) superfamily: new members, new functions, and novel paradigms R Meech, DG Hu, RA McKinnon, SN Mubarokah, AZ Haines, PC Nair, ... Physiological Reviews 99 (2), 1153-1222, 2019 | 276 | 2019 |
Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance JO Miners, RA McKinnon, PI Mackenzie Toxicology 181, 453-456, 2002 | 276 | 2002 |
Predicting human drug glucuronidation parameters: application of in vitro and in silico modeling approaches JO Miners, PA Smith, MJ Sorich, RA McKinnon, PI Mackenzie Annu. Rev. Pharmacol. Toxicol. 44 (1), 1-25, 2004 | 249 | 2004 |
Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues. RA McKinnon, WM Burgess, PM Hall, SJ Roberts-Thomson, FJ Gonzalez, ... Gut 36 (2), 259-267, 1995 | 205 | 1995 |
Cyp1a2 (-/-) null mutant mice develop normally but show deficient drug metabolism. HC Liang, H Li, RA McKinnon, JJ Duffy, SS Potter, A Puga, DW Nebert Proceedings of the National Academy of Sciences 93 (4), 1671-1676, 1996 | 204 | 1996 |
Predicting response and toxicity to immune checkpoint inhibitors using routinely available blood and clinical markers AM Hopkins, A Rowland, G Kichenadasse, MD Wiese, H Gurney, ... British Journal of Cancer 117 (7), 913-920, 2017 | 176 | 2017 |
The role of xenobiotic metabolizing enzymes in arylamine toxicity and carcinogenesis: functional and localization studies KF Windmill, RA McKinnon, X Zhu, A Gaedigk, DM Grant, ME McManus Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 376 (1 …, 1997 | 166 | 1997 |
Manipulation of the gut microbiota using resistant starch is associated with protection against colitis-associated colorectal cancer in rats Y Hu, RK Le Leu, CT Christophersen, R Somashekar, MA Conlon, ... Carcinogenesis 37 (4), 366-375, 2016 | 162 | 2016 |
CYP2C19 Genotype Has a Greater Effect on Adverse Cardiovascular Outcomes Following Percutaneous Coronary Intervention and in Asian Populations Treated … MJ Sorich, A Rowland, RA McKinnon, MD Wiese Circulation: cardiovascular genetics 7 (6), 895-902, 2014 | 151 | 2014 |
Comparison of linear and nonlinear classification algorithms for the prediction of drug and chemical metabolism by human UDP-glucuronosyltransferase isoforms MJ Sorich, JO Miners, RA McKinnon, DA Winkler, FR Burden, PA Smith Journal of chemical information and computer sciences 43 (6), 2019-2024, 2003 | 141 | 2003 |
Complementary and alternative medicines and dietary interventions in multiple sclerosis: what is being used in South Australia and why? EM Leong, SJ Semple, M Angley, W Siebert, J Petkov, RA McKinnon Complementary therapies in medicine 17 (4), 216-223, 2009 | 137 | 2009 |
Transcriptional regulation of human UDP-glucuronosyltransferase genes DG Hu, R Meech, RA McKinnon, PI Mackenzie Drug metabolism reviews 46 (4), 421-458, 2014 | 132 | 2014 |
Prasugrel vs. clopidogrel for cytochrome P450 2C19‐genotyped subgroups: integration of the TRITON‐TIMI 38 trial data MJ Sorich, A Vitry, MB Ward, JD Horowitz, RA McKinnon Journal of Thrombosis and Haemostasis 8 (8), 1678-1684, 2010 | 129 | 2010 |
Polymorphisms in UDP glucuronosyltransferase genes: functional consequences and clinical relevance PI Mackenzie, JO Miners, RA McKinnon Walter de Gruyter 38 (9), 889-892, 2000 | 123 | 2000 |
Biosimilarity and interchangeability: principles and evidence: a systematic review RA McKinnon, M Cook, W Liauw, M Marabani, IC Marschner, NH Packer, ... BioDrugs 32, 27-52, 2018 | 117 | 2018 |
miR-18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells KJ Humphreys, RA McKinnon, MZ Michael PloS one 9 (11), e112288, 2014 | 108 | 2014 |
Cytochrome P450: Evolution and functional variability D Nebert, R McKinnon Progress in liver diseases 12, 63-97, 1994 | 105 | 1994 |