Tetrathiomolybdate inhibits copper trafficking proteins through metal cluster formation HM Alvarez, Y Xue, CD Robinson, MA Canalizo-Hernández, RG Marvin, ... Science 327 (5963), 331-334, 2010 | 190 | 2010 |
Modeling Nickel Hydrogenases: Synthesis and Structure of a Distorted Octahedral Complex with an Unprecedented [NiS4H2] Core HM Alvarez, M Krawiec, BT Donovan-Merkert, M Fouzi, D Rabinovich Inorganic Chemistry 40 (23), 5736-5737, 2001 | 84 | 2001 |
Homoleptic Group 12 Metal Bis(mercaptoimidazolyl)borate Complexes M(BmR)2 (M = Zn, Cd, Hg) HM Alvarez, TB Tran, MA Richter, DM Alyounes, D Rabinovich, JM Tanski, ... Inorganic chemistry 42 (6), 2149-2156, 2003 | 74 | 2003 |
An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy S Chan, N Belmar, S Ho, B Rogers, M Stickler, M Graham, E Lee, N Tran, ... Nature cancer 3 (3), 337-354, 2022 | 54 | 2022 |
Poly (mercaptoimidazolyl) borate chemistry and the predominance of κ3-S, S, H over κ2-S, S or κ3-S, S, S coordination modes: unexpected formation of square pyramidal Ni (II … HM Alvarez, JM Tanski, D Rabinovich Polyhedron 23 (2-3), 395-403, 2004 | 47 | 2004 |
Thallium (I) bis (mercaptoimidazolyl) borates HM Alvarez, PA Gillespie, CD Gause, AL Rheingold, JA Golen, ... Polyhedron 23 (4), 617-622, 2004 | 37 | 2004 |
Epitope and Fc-mediated cross-linking, but not high affinity, are critical for antitumor activity of CD137 agonist antibody with reduced liver toxicity SK Ho, Z Xu, A Thakur, M Fox, SS Tan, E DiGiammarino, L Zhou, M Sho, ... Molecular cancer therapeutics 19 (4), 1040-1051, 2020 | 35 | 2020 |
Effects of PEGylation and immune complex formation on the pharmacokinetics and biodistribution of recombinant interleukin 10 in mice HM Alvarez, OY So, SC Hsieh, N Shinsky-Bjorde, H Ma, Y Song, Y Pang, ... Drug Metabolism and Disposition 40 (2), 360-373, 2012 | 32 | 2012 |
Murinization and H chain isotype matching of the anti-Gitr antibody Dta-1 reduces immunogenicity-mediated anaphylaxis in C57bl/6 mice NA Belmar, SW Chan, MI Fox, JA Samayoa, MM Stickler, NN Tran, ... The Journal of Immunology 198 (11), 4502-4512, 2017 | 6 | 2017 |
Evaluation of efficacy metrics for in vivo experiments with immuno-oncology therapeutic agents C Zhang, Y Sun, HM Alvarez, Y Akamatsu, F Harding, SS Tan, M Fox, ... Cancer Research 80 (16_Supplement), 1615-1615, 2020 | | 2020 |
Structural implications for GITR agonism in immunotherapies H Alvarez, B Rogers, S Chan, L Bigelow, S Cichanowicz, M Lake, ... JOURNAL FOR IMMUNOTHERAPY OF CANCER 7, 2019 | | 2019 |
Murinization of an anti-GITR IgG2c antibody DTA-1 inhibits immunogenicity-mediated anaphylaxis in C57BL/6J mice H Alvarez, N Belmar, M Fox, J Samayoa, S Chan, D Hollenbaugh, ... Journal for ImmunoTherapy of Cancer 3 (Suppl 2), P182, 2015 | | 2015 |
The Role of FcRn in the Disposition, Metabolism and Pharmacokinetics of Soluble Non‐Crosslinking Immune Complexes HM Alvarez, OY So, SC Hsieh, N Shinsky‐Bjorde, H Ma, Y Song, Y Pang, ... The FASEB Journal 27, 270.7-270.7, 2013 | | 2013 |
Insights on the intracellular mechanism of action of the anticancer and antiangiogenic copper chelator drug: Ammonium tetrathiomolybdate (TM) HM Alvarez Northwestern University, 2008 | | 2008 |
Insights on the molecular mechanism of action of the antiangiogenic copper chelator drug: ammonium tetrathiomolybdate HM Alvarez, TV O'Halloran, R Kelly, JE Penner-Hahn, B Lai ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 233, 461-461, 2007 | | 2007 |
CCDC 208142: Experimental Crystal Structure Determination MA Richter, DM Alyounes, M Krawiec, TB Tran, JM Tanski, D Rabinovich, ... The Cambridge Structural Database, 2003 | | 2003 |
CCDC 208145: Experimental Crystal Structure Determination D Rabinovich, MA Richter, HM Alvarez, JM Tanski, M Krawiec, ... The Cambridge Structural Database, 2003 | | 2003 |
Five-coordinate nickel poly (mercaptoimidazolyl) borate complexes. HM Alvarez, JM Tanski, D Rabinovich ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 224, U677-U677, 2002 | | 2002 |
Bis (mercaptoimidazolyl) borate complexes. HM Alvarez, D Rabinovich ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 223, A16-A16, 2002 | | 2002 |
New synthetic models of nickel hydrogenases. D Rabinovich, HM Alvarez ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 223, A68-A68, 2002 | | 2002 |