Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry Y Ho, A Gruhler, A Heilbut, GD Bader, L Moore, SL Adams, A Millar, ... Nature 415 (6868), 180-183, 2002 | 4595 | 2002 |
The CRAPome: a contaminant repository for affinity purification–mass spectrometry data D Mellacheruvu, Z Wright, AL Couzens, JP Lambert, NA St-Denis, T Li, ... Nature methods 10 (8), 730-736, 2013 | 1735 | 2013 |
High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015 | 1634 | 2015 |
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins C Doil, N Mailand, S Bekker-Jensen, P Menard, DH Larsen, R Pepperkok, ... Cell 136 (3), 435-446, 2009 | 1083 | 2009 |
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase NK Kolas, JR Chapman, S Nakada, J Ylanko, R Chahwan, FD Sweeney, ... Science 318 (5856), 1637, 2007 | 1072 | 2007 |
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice C Escribano-Díaz, A Orthwein, A Fradet-Turcotte, M Xing, JTF Young, ... Molecular cell 49 (5), 872-883, 2013 | 1035 | 2013 |
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage GS Stewart, S Panier, K Townsend, AK Al-Hakim, NK Kolas, ES Miller, ... Cell 136 (3), 420-434, 2009 | 865 | 2009 |
The cardiac transcription factors Nkx2‐5 and GATA‐4 are mutual cofactors D Durocher, F Charron, R Warren, RJ Schwartz, M Nemer The EMBO journal, 1997 | 849 | 1997 |
The control of DNA repair by the cell cycle N Hustedt, D Durocher Nature cell biology 19 (1), 1-9, 2017 | 762 | 2017 |
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark A Fradet-Turcotte, MD Canny, C Escribano-Díaz, A Orthwein, CCY Leung, ... Nature 499 (7456), 50-54, 2013 | 747 | 2013 |
DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme? D Durocher, SP Jackson Current opinion in cell biology 13 (2), 225-231, 2001 | 740 | 2001 |
Regulation of DNA damage responses by ubiquitin and SUMO SP Jackson, D Durocher Molecular cell 49 (5), 795-807, 2013 | 712 | 2013 |
A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery MC Keogh, JA Kim, M Downey, J Fillingham, D Chowdhury, JC Harrison, ... Nature 439 (7075), 497-501, 2005 | 628 | 2005 |
The shieldin complex mediates 53BP1-dependent DNA repair SM Noordermeer, S Adam, D Setiaputra, M Barazas, SJ Pettitt, AK Ling, ... Nature 560 (7716), 117-121, 2018 | 556 | 2018 |
The molecular basis of FHA domain: phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms D Durocher, IA Taylor, D Sarbassova, LF Haire, SL Westcott, SP Jackson, ... Molecular cell 6 (5), 1169-1182, 2000 | 549 | 2000 |
A mechanism for the suppression of homologous recombination in G1 cells A Orthwein, SM Noordermeer, MD Wilson, S Landry, RI Enchev, ... Nature 528 (7582), 422-426, 2015 | 543 | 2015 |
The FHA domain D Durocher, SP Jackson FEBS letters 513 (1), 58-66, 2002 | 526 | 2002 |
The FHA domain is a modular phosphopeptide recognition motif D Durocher, J Henckel, AR Fersht, SP Jackson Molecular cell 4 (3), 387-394, 1999 | 510 | 1999 |
Evaluation and design of genome-wide CRISPR/SpCas9 knockout screens T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ... G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017 | 496 | 2017 |
A genetic map of the response to DNA damage in human cells M Olivieri, T Cho, A Álvarez-Quilón, K Li, MJ Schellenberg, ... Cell 182 (2), 481-496. e21, 2020 | 398 | 2020 |