| Metastability of native proteins and the phenomenon of amyloid formation AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ... Journal of the American Chemical Society 133 (36), 14160-14163, 2011 | 504 | 2011 |
| Plasticity of an ultrafast interaction between nucleoporins and nuclear transport receptors S Milles, D Mercadante, IV Aramburu, MR Jensen, N Banterle, C Koehler, ... Cell 163 (3), 734-745, 2015 | 286 | 2015 |
| A mechanistic model of tau amyloid aggregation based on direct observation of oligomers SL Shammas, GA Garcia, S Kumar, M Kjaergaard, MH Horrocks, N Shivji, ... Nature communications 6 (1), 7025, 2015 | 217 | 2015 |
| Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ... Biophysical journal 101 (7), 1681-1689, 2011 | 185 | 2011 |
| Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein JM Rogers, V Oleinikovas, SL Shammas, CT Wong, D De Sancho, ... Proceedings of the National Academy of Sciences 111 (43), 15420-15425, 2014 | 156 | 2014 |
| Insights into coupled folding and binding mechanisms from kinetic studies SL Shammas, MD Crabtree, L Dahal, BIM Wicky, J Clarke Journal of Biological Chemistry 291 (13), 6689-6695, 2016 | 155 | 2016 |
| Perturbation of the stability of amyloid fibrils through alteration of electrostatic interactions SL Shammas, TPJ Knowles, AJ Baldwin, CE MacPhee, ME Welland, ... Biophysical journal 100 (11), 2783-2791, 2011 | 155 | 2011 |
| Transient misfolding dominates multidomain protein folding A Borgia, KR Kemplen, MB Borgia, A Soranno, S Shammas, B Wunderlich, ... Nature communications 6 (1), 8861, 2015 | 117 | 2015 |
| Remarkably fast coupled folding and binding of the intrinsically disordered transactivation domain of cMyb to CBP KIX SL Shammas, AJ Travis, J Clarke The journal of physical chemistry B 117 (42), 13346-13356, 2013 | 103 | 2013 |
| Hsp70 inhibits the nucleation and elongation of tau and sequesters tau aggregates with high affinity F Kundel, S De, P Flagmeier, MH Horrocks, M Kjaergaard, SL Shammas, ... ACS chemical biology 13 (3), 636-646, 2018 | 102 | 2018 |
| Affinity of IDPs to their targets is modulated by ion-specific changes in kinetics and residual structure BIM Wicky, SL Shammas, J Clarke Proceedings of the National Academy of Sciences 114 (37), 9882-9887, 2017 | 89 | 2017 |
| Allostery within a transcription coactivator is predominantly mediated through dissociation rate constants SL Shammas, AJ Travis, J Clarke Proceedings of the National Academy of Sciences 111 (33), 12055-12060, 2014 | 85 | 2014 |
| Mechanistic roles of protein disorder within transcription SL Shammas Current opinion in structural biology 42, 155-161, 2017 | 70 | 2017 |
| Intrinsic determinants of neurotoxic aggregate formation by the amyloid β peptide AC Brorsson, B Bolognesi, GG Tartaglia, SL Shammas, G Favrin, I Watson, ... Biophysical journal 98 (8), 1677-1684, 2010 | 59 | 2010 |
| Conserved helix-flanking prolines modulate intrinsically disordered protein: target affinity by altering the lifetime of the bound complex MD Crabtree, W Borcherds, A Poosapati, SL Shammas, GW Daughdrill, ... Biochemistry 56 (18), 2379-2384, 2017 | 47 | 2017 |
| Separating the effects of internal friction and transition state energy to explain the slow, frustrated folding of spectrin domains BG Wensley, LG Kwa, SL Shammas, JM Rogers, S Browning, Z Yang, ... Proceedings of the National Academy of Sciences 109 (44), 17795-17799, 2012 | 47 | 2012 |
| Slow, reversible, coupled folding and binding of the spectrin tetramerization domain SL Shammas, JM Rogers, SA Hill, J Clarke Biophysical journal 103 (10), 2203-2214, 2012 | 45 | 2012 |
| Two differential binding mechanisms of FG-nucleoporins and nuclear transport receptors PS Tan, IV Aramburu, D Mercadante, S Tyagi, A Chowdhury, D Spitz, ... Cell reports 22 (13), 3660-3671, 2018 | 44 | 2018 |
| pKID binds to KIX via an unstructured transition state with nonnative interactions L Dahal, TOC Kwan, SL Shammas, J Clarke Biophysical journal 113 (12), 2713-2722, 2017 | 42 | 2017 |
| Role of non-native electrostatic interactions in the coupled folding and binding of PUMA with Mcl-1 WT Chu, J Clarke, SL Shammas, J Wang PLoS computational biology 13 (4), e1005468, 2017 | 38 | 2017 |
