Expanded encyclopaedias of DNA elements in the human and mouse genomes JE Moore, MJ Purcaro, HE Pratt, CB Epstein, N Shoresh, J Adrian, T Kawli, ... Nature 583 (7818), 699-710, 2020 | 1457 | 2020 |
Interaction of tau with the RNA-binding protein TIA1 regulates tau pathophysiology and toxicity T Vanderweyde, DJ Apicco, K Youmans-Kidder, PEA Ash, C Cook, ... Cell reports 15 (7), 1455-1466, 2016 | 312 | 2016 |
NEMO prevents RIP kinase 1-mediated epithelial cell death and chronic intestinal inflammation by NF-κB-dependent and-independent functions K Vlantis, A Wullaert, A Polykratis, V Kondylis, M Dannappel, R Schwarzer, ... Immunity 44 (3), 553-567, 2016 | 189 | 2016 |
Evolutionary constraint and innovation across hundreds of placental mammals MJ Christmas, IM Kaplow, DP Genereux, MX Dong, GM Hughes, X Li, ... Science 380 (6643), eabn3943, 2023 | 143 | 2023 |
A curated benchmark of enhancer-gene interactions for evaluating enhancer-target gene prediction methods JE Moore, HE Pratt, MJ Purcaro, Z Weng Genome biology 21, 1-16, 2020 | 105 | 2020 |
Integrating gene annotation with orthology inference at scale BM Kirilenko, C Munegowda, E Osipova, D Jebb, V Sharma, M Blumer, ... Science 380 (6643), eabn3107, 2023 | 78 | 2023 |
A genomic timescale for placental mammal evolution NM Foley, VC Mason, AJ Harris, KR Bredemeyer, J Damas, HA Lewin, ... Science 380 (6643), eabl8189, 2023 | 74 | 2023 |
YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation L He, H Pratt, M Gao, F Wei, Z Weng, K Struhl Elife 10, e67312, 2021 | 74 | 2021 |
Leveraging base-pair mammalian constraint to understand genetic variation and human disease PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li, DP Genereux, ... Science 380 (6643), eabn2937, 2023 | 71 | 2023 |
Annotation of chromatin states in 66 complete mouse epigenomes during development A van der Velde, K Fan, J Tsuji, JE Moore, MJ Purcaro, HE Pratt, Z Weng Communications Biology 4 (1), 239, 2021 | 59 | 2021 |
Three-dimensional genome rewiring in loci with human accelerated regions KC Keough, S Whalen, F Inoue, PF Przytycki, T Fair, C Deng, M Steyert, ... Science 380 (6643), eabm1696, 2023 | 57 | 2023 |
Genome-wide analysis of immune system genes by expressed sequence Tag profiling CC Giallourakis, Y Benita, B Molinie, Z Cao, O Despo, HE Pratt, ... The Journal of Immunology 190 (11), 5578-5587, 2013 | 53 | 2013 |
Mammalian evolution of human cis-regulatory elements and transcription factor binding sites G Andrews, K Fan, HE Pratt, N Phalke, Zoonomia Consortium §, ... Science 380 (6643), eabn7930, 2023 | 51 | 2023 |
Differential analysis of chromatin accessibility and histone modifications for predicting mouse developmental enhancers S Fu, Q Wang, JE Moore, MJ Purcaro, HE Pratt, K Fan, C Gu, C Jiang, ... Nucleic acids research 46 (21), 11184-11201, 2018 | 50 | 2018 |
Relating enhancer genetic variation across mammals to complex phenotypes using machine learning IM Kaplow, AJ Lawler, DE Schäffer, C Srinivasan, HH Sestili, ME Wirthlin, ... Science 380 (6643), eabm7993, 2023 | 49 | 2023 |
Insights into mammalian TE diversity through the curation of 248 genome assemblies AB Osmanski, NS Paulat, J Korstian, JR Grimshaw, M Halsey, ... Science 380 (6643), eabn1430, 2023 | 47 | 2023 |
HELZ2 is an IFN effector mediating suppression of dengue virus DN Fusco, H Pratt, S Kandilas, SSY Cheon, W Lin, DA Cronkite, ... Frontiers in microbiology 8, 240, 2017 | 43 | 2017 |
The contribution of historical processes to contemporary extinction risk in placental mammals AP Wilder, MA Supple, A Subramanian, A Mudide, R Swofford, ... Science 380 (6643), eabn5856, 2023 | 42 | 2023 |
The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models J Rozowsky, J Gao, B Borsari, YT Yang, T Galeev, G Gürsoy, CB Epstein, ... Cell 186 (7), 1493-1511. e40, 2023 | 33 | 2023 |
Single-cell multi-cohort dissection of the schizophrenia transcriptome WB Ruzicka, S Mohammadi, JF Fullard, J Davila-Velderrain, S Subburaju, ... Science 384 (6698), eadg5136, 2024 | 31 | 2024 |