Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover AJ Callaghan, MJ Marcaida, JA Stead, KJ McDowall, WG Scott, BF Luisi Nature 437 (7062), 1187-1191, 2005 | 326 | 2005 |
Oxypurinol directly and immediately activates the drug-specific T cells via the preferential use of HLA-B* 58: 01 J Yun, MJ Marcaida, KK Eriksson, H Jamin, S Fontana, WJ Pichler, ... The Journal of Immunology 192 (7), 2984-2993, 2014 | 183 | 2014 |
The RNA degradosome: life in the fast lane of adaptive molecular evolution MJ Marcaida, MA DePristo, V Chandran, AJ Carpousis, BF Luisi Trends in biochemical sciences 31 (7), 359-365, 2006 | 146 | 2006 |
Homing endonucleases: from basics to therapeutic applications MJ Marcaida, IG Muñoz, FJ Blanco, J Prieto, G Montoya Cellular and Molecular Life Sciences 67, 727-748, 2010 | 111 | 2010 |
Molecular basis of histone H3K4me3 recognition by ING4 A Palacios, IG Muñoz, D Pantoja-Uceda, MJ Marcaida, D Torres, ... Journal of biological chemistry 283 (23), 15956-15964, 2008 | 95 | 2008 |
The crystal structure of the Escherichia coli RNase E apoprotein and a mechanism for RNA degradation DJ Koslover, AJ Callaghan, MJ Marcaida, EF Garman, M Martick, ... Structure 16 (8), 1238-1244, 2008 | 92 | 2008 |
Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores C Cao, N Cirauqui, MJ Marcaida, E Buglakova, A Duperrex, A Radenovic, ... Nature communications 10 (1), 4918, 2019 | 90 | 2019 |
Discovery of a selective aurora a kinase inhibitor by virtual screening F Kilchmann, MJ Marcaida, S Kotak, T Schick, SD Boss, M Awale, ... Journal of medicinal chemistry 59 (15), 7188-7211, 2016 | 67 | 2016 |
Modulation of Heme Redox Potential in the Cytochrome c6 Family JAR Worrall, BG Schlarb-Ridley, T Reda, MJ Marcaida, RJ Moorlen, ... Journal of the American Chemical Society 129 (30), 9468-9475, 2007 | 58 | 2007 |
Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering MJ Marcaida, J Prieto, P Redondo, AD Nadra, A Alibés, L Serrano, ... Proceedings of the National Academy of Sciences 105 (44), 16888-16893, 2008 | 47 | 2008 |
Bridged bicyclic peptides as potential drug scaffolds: synthesis, structure, protein binding and stability M Bartoloni, X Jin, MJ Marcaida, J Banha, I Dibonaventura, S Bongoni, ... Chemical science 6 (10), 5473-5490, 2015 | 42 | 2015 |
Visualizing phosphodiester-bond hydrolysis by an endonuclease R Molina, S Stella, P Redondo, H Gomez, MJ Marcaida, M Orozco, ... Nature structural & molecular biology 22 (1), 65-72, 2015 | 42 | 2015 |
Structure of cytochrome c6A, a novel dithio-cytochrome of Arabidopsis thaliana, and its reactivity with plastocyanin: implications for function MJ Marcaida, BG Schlarb-Ridley, JAR Worrall, J Wastl, TJ Evans, ... Journal of molecular biology 360 (5), 968-977, 2006 | 41 | 2006 |
Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains L Abrami, M Audagnotto, S Ho, MJ Marcaida, FS Mesquita, MU Anwar, ... Nature chemical biology 17 (4), 438-447, 2021 | 37 | 2021 |
Solution structure of human growth arrest and DNA damage 45α (Gadd45α) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase R Sánchez, D Pantoja-Uceda, J Prieto, T Diercks, MJ Marcaida, ... Journal of biological chemistry 285 (29), 22196-22201, 2010 | 35 | 2010 |
Structural insights on cholesterol endosynthesis: Binding of squalene and 2, 3-oxidosqualene to supernatant protein factor M Christen, MJ Marcaida, C Lamprakis, W Aeschimann, J Vaithilingam, ... Journal of structural biology 190 (3), 261-270, 2015 | 28 | 2015 |
The polyglutamine expansion at the N-terminal of Huntingtin protein modulates the dynamic configuration and phosphorylation of the C-terminal HEAT domain T Jung, B Shin, G Tamo, H Kim, R Vijayvargia, A Leitner, MJ Marcaida, ... Structure 28 (9), 1035-1050. e8, 2020 | 24 | 2020 |
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms DP Duarte, AJ Lamontanara, G La Sala, S Jeong, YK Sohn, A Panjkovich, ... Nature communications 11 (1), 2319, 2020 | 24 | 2020 |
KAP1 is an antiparallel dimer with a functional asymmetry G Fonti, MJ Marcaida, LC Bryan, S Träger, AS Kalantzi, PYJL Helleboid, ... Life science alliance 2 (4), 2019 | 19 | 2019 |
The human RNA helicase DDX21 presents a dimerization interface necessary for helicase activity MJ Marcaida, A Kauzlaric, A Duperrex, J Sülzle, MC Moncrieffe, ... Iscience 23 (12), 2020 | 18 | 2020 |