Cardioprotection and lifespan extension by the natural polyamine spermidine T Eisenberg, M Abdellatif, S Schroeder, U Primessnig, S Stekovic, T Pendl, ... Nature medicine 22 (12), 1428-1438, 2016 | 972 | 2016 |
Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA K Panzitt, MMO Tschernatsch, C Guelly, T Moustafa, M Stradner, ... Gastroenterology 132 (1), 330-342, 2007 | 906 | 2007 |
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1 G Haemmerle, T Moustafa, G Woelkart, S Büttner, A Schmidt, ... Nature medicine 17 (9), 1076-1085, 2011 | 765 | 2011 |
A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis P Fickert, U Stöger, A Fuchsbichler, T Moustafa, HU Marschall, ... The American journal of pathology 171 (2), 525-536, 2007 | 400 | 2007 |
Bile acids as regulators of hepatic lipid and glucose metabolism M Trauner, T Claudel, P Fickert, T Moustafa, M Wagner Digestive diseases 28 (1), 220-224, 2010 | 372 | 2010 |
Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTα-OSTβ in cholestasis in humans and rodents JL Boyer, M Trauner, A Mennone, CJ Soroka, SY Cai, T Moustafa, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 290 (6 …, 2006 | 349 | 2006 |
Selective activation of nuclear bile acid receptor FXR in the intestine protects mice against cholestasis S Modica, M Petruzzelli, E Bellafante, S Murzilli, L Salvatore, N Celli, ... Gastroenterology 142 (2), 355-365. e4, 2012 | 296 | 2012 |
Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan T Eisenberg, S Schroeder, A Andryushkova, T Pendl, V Küttner, A Bhukel, ... Cell metabolism 19 (3), 431-444, 2014 | 275 | 2014 |
Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae BT Weinert, V Iesmantavicius, T Moustafa, C Schölz, SA Wagner, ... Molecular systems biology 10 (1), 716, 2014 | 267 | 2014 |
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-α/β in the adaptive response to bile acids G Zollner, M Wagner, T Moustafa, P Fickert, D Silbert, J Gumhold, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 290 (5 …, 2006 | 214 | 2006 |
PCK2 activation mediates an adaptive response to glucose depletion in lung cancer K Leithner, A Hrzenjak, M Trötzmüller, T Moustafa, HC Köfeler, ... Oncogene 34 (8), 1044-1050, 2015 | 201 | 2015 |
Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts P Fickert, A Fuchsbichler, T Moustafa, M Wagner, G Zollner, E Halilbasic, ... The American journal of pathology 175 (6), 2392-2405, 2009 | 183 | 2009 |
Bile acids trigger cholemic nephropathy in common bile‐duct–ligated mice P Fickert, E Krones, MJ Pollheimer, A Thueringer, T Moustafa, D Silbert, ... Hepatology 58 (6), 2056-2069, 2013 | 175 | 2013 |
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury T Moustafa, P Fickert, C Magnes, C Guelly, A Thueringer, S Frank, ... Gastroenterology 142 (1), 140-151. e12, 2012 | 174 | 2012 |
Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2−/− mice E Halilbasic, R Fiorotto, P Fickert, HU Marschall, T Moustafa, C Spirli, ... Hepatology 49 (6), 1972-1981, 2009 | 164 | 2009 |
Analysis of acetylation stoichiometry suggests that SIRT 3 repairs nonenzymatic acetylation lesions BT Weinert, T Moustafa, V Iesmantavicius, R Zechner, C Choudhary The EMBO journal 34 (21), 2620-2632, 2015 | 144 | 2015 |
Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases M Trauner, P Fickert, E Halilbasic, T Moustafa WMW Wiener Medizinische Wochenschrift 158 (19), 542-548, 2008 | 144 | 2008 |
Differential effects of norUDCA and UDCA in obstructive cholestasis in mice P Fickert, MJ Pollheimer, D Silbert, T Moustafa, E Halilbasic, E Krones, ... Journal of hepatology 58 (6), 1201-1208, 2013 | 100 | 2013 |
TORC1 promotes phosphorylation of ribosomal protein S6 via the AGC kinase Ypk3 in Saccharomyces cerevisiae A González, M Shimobayashi, T Eisenberg, DA Merle, T Pendl, MN Hall, ... PloS one 10 (3), e0120250, 2015 | 93 | 2015 |
Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis MK Brahma, RC Adam, NM Pollak, D Jaeger, KA Zierler, N Pöcher, ... Journal of lipid research 55 (11), 2229-2241, 2014 | 68 | 2014 |