| Characteristics of photoreceptor PDE (PDE6): similarities and differences to PDE5 RH Cote International journal of impotence research 16 (1), S28-S33, 2004 | 214 | 2004 |
| Isolation and Characterization of Rifampin-Resistant and Streptolydigin-Resistant Mutants of Bacillus subtilis with Altered Sporulation Properties AL Sonenshein, B Cami, J Brevet, R Cote Journal of bacteriology 120 (1), 253-265, 1974 | 145 | 1974 |
| Efficacy and selectivity of phosphodiesterase-targeted drugs in inhibiting photoreceptor phosphodiesterase (PDE6) in retinal photoreceptors X Zhang, Q Feng, RH Cote Investigative ophthalmology & visual science 46 (9), 3060-3066, 2005 | 133 | 2005 |
| cGMP binding sites on photoreceptor phosphodiesterase: role in feedback regulation of visual transduction. RH Cote, MD Bownds, VY Arshavsky Proceedings of the National Academy of Sciences 91 (11), 4845-4849, 1994 | 118 | 1994 |
| Light-induced decreases in cGMP concentration precede changes in membrane permeability in frog rod photoreceptors. RH Cote, MS Biernbaum, GD Nicol, MD Bownds Journal of biological Chemistry 259 (15), 9635-9641, 1984 | 114 | 1984 |
| Molecular organization of bovine rod cGMP-phosphodiesterase 6 JFK Tcheudji, L Lebeau, N Virmaux, CG Maftei, RH Cote, C Lugnier, ... Journal of molecular biology 310 (4), 781-791, 2001 | 110 | 2001 |
| The catalytic and GAF domains of the rod cGMP phosphodiesterase (PDE6) heterodimer are regulated by distinct regions of its inhibitory γ subunit H Mou, RH Cote Journal of Biological Chemistry 276 (29), 27527-27534, 2001 | 104 | 2001 |
| cGMP signaling in vertebrate retinal photoreceptor cells X Zhang, RH Cote Front Biosci 10 (1-3), 1191-1204, 2005 | 98 | 2005 |
| cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its γ and δ subunits H Mou, HJ Grazio, TA Cook, JA Beavo, RH Cote Journal of Biological Chemistry 274 (26), 18813-18820, 1999 | 89 | 1999 |
| Intracellular cGMP concentration in rod photoreceptors is regulated by binding to high and moderate affinity cGMP binding sites RH Cote, MA Brunnock Journal of Biological Chemistry 268 (23), 17190-17198, 1993 | 87 | 1993 |
| Evaluation of the 17-kDa prenyl-binding protein as a regulatory protein for phototransduction in retinal photoreceptors AW Norton, S Hosier, JM Terew, N Li, A Dhingra, N Vardi, W Baehr, ... Journal of Biological Chemistry 280 (2), 1248-1256, 2005 | 75 | 2005 |
| Head-to-tail polymerization of microtubules in vitro RH Cote, GG Borisy Journal of molecular biology 150 (4), 577-599, 1981 | 74 | 1981 |
| Mechanism of transducin activation of frog rod photoreceptor phosphodiesterase: allosteric interactions between the inhibitory γ subunit and the noncatalytic cGMP-binding sites AW Norton, MR D'Amours, HJ Grazio, TL Hebert, RH Cote Journal of Biological Chemistry 275 (49), 38611-38619, 2000 | 64 | 2000 |
| Regulation of photoreceptor phosphodiesterase catalysis by its non-catalytic cGMP-binding sites MR D'AMOURS, RH Cote Biochemical Journal 340 (3), 863-869, 1999 | 61 | 1999 |
| Photoreceptor phosphodiesterase (PDE6): a G-protein-activated PDE regulating visual excitation in rod and cone photoreceptor cells RH Cote Cyclic nucleotide phosphodiesterases in health and disease, 165-193, 2006 | 54 | 2006 |
| Photoreceptor phosphodiesterase: interaction of inhibitory γ subunit and cyclic GMP with specific binding sites on catalytic subunits NO Artemyev, VY Arshavsky, RH Cote Methods 14 (1), 93-104, 1998 | 51 | 1998 |
| Molecular architecture of photoreceptor phosphodiesterase elucidated by chemical cross-linking and integrative modeling X Zeng-Elmore, XZ Gao, R Pellarin, D Schneidman-Duhovny, XJ Zhang, ... Journal of molecular biology 426 (22), 3713-3728, 2014 | 50 | 2014 |
| The glutamic acid-rich protein-2 (GARP2) is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties DC Pentia, S Hosier, RH Cote Journal of biological chemistry 281 (9), 5500-5505, 2006 | 50 | 2006 |
| Regulation of photoreceptor phosphodiesterase (PDE6) by phosphorylation of its inhibitory γ subunit re-evaluated MJ Paglia, H Mou, RH Cote Journal of Biological Chemistry 277 (7), 5017-5023, 2002 | 41 | 2002 |
| Identification of amino acid residues responsible for the selectivity of tadalafil binding to two closely related phosphodiesterases, PDE5 and PDE6 KB Cahill, JH Quade, KL Carleton, RH Cote Journal of Biological Chemistry 287 (49), 41406-41416, 2012 | 40 | 2012 |
Xiong-Zhuo Gao在 merck.com 的电子邮件经过验证
