| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13252* | 2021 |
| Parkin ubiquitinates the α-synuclein–interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease KKK Chung, Y Zhang, KL Lim, Y Tanaka, H Huang, J Gao, CA Ross, ... Nature medicine 7 (10), 1144-1150, 2001 | 982 | 2001 |
| Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity AB West, DJ Moore, C Choi, SA Andrabi, X Li, D Dikeman, S Biskup, ... Human molecular genetics 16 (2), 223-232, 2007 | 706 | 2007 |
| Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation KL Lim, KCM Chew, JMM Tan, C Wang, KKK Chung, Y Zhang, Y Tanaka, ... Journal of Neuroscience 25 (8), 2002-2009, 2005 | 633 | 2005 |
| Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy JY Lee, Y Nagano, JP Taylor, KL Lim, TP Yao Journal of Cell Biology 189 (4), 671-679, 2010 | 631 | 2010 |
| Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases JMM Tan, ESP Wong, DS Kirkpatrick, O Pletnikova, HS Ko, SP Tay, ... Human molecular genetics 17 (3), 431-439, 2008 | 547 | 2008 |
| Loss of locus coeruleus neurons and reduced startle in parkin null mice R Von Coelln, B Thomas, JM Savitt, KL Lim, M Sasaki, EJ Hess, ... Proceedings of the National Academy of Sciences 101 (29), 10744-10749, 2004 | 413 | 2004 |
| Intraparticle Energy Level Alignment of Semiconducting Polymer Nanoparticles to Amplify Chemiluminescence for Ultrasensitive In Vivo Imaging of Reactive … X Zhen, C Zhang, C Xie, Q Miao, KL Lim, K Pu ACS nano 10 (6), 6400-6409, 2016 | 290 | 2016 |
| Targeted disruption of the tyrosine phosphatase PTPα leads to constitutive downregulation of the kinases Src and Fyn S Ponniah, DZM Wang, KL Lim, CJ Pallen Current Biology 9 (10), 535-538, 1999 | 268 | 1999 |
| Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila CH Ng, SZS Mok, C Koh, X Ouyang, ML Fivaz, EK Tan, VL Dawson, ... Journal of Neuroscience 29 (36), 11257-11262, 2009 | 248 | 2009 |
| Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function C Wang, HS Ko, B Thomas, F Tsang, KCM Chew, SP Tay, MWL Ho, ... Human molecular genetics 14 (24), 3885-3897, 2005 | 244 | 2005 |
| Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin SR Sriram, X Li, HS Ko, KKK Chung, E Wong, KL Lim, VL Dawson, ... Human molecular genetics 14 (17), 2571-2586, 2005 | 242 | 2005 |
| Reactive oxygen species trigger Parkin/PINK1 pathway–dependent mitophagy by inducing mitochondrial recruitment of Parkin B Xiao, JY Goh, L Xiao, H Xian, KL Lim, YC Liou Journal of Biological Chemistry 292 (40), 16697-16708, 2017 | 217 | 2017 |
| Autophagy-mediated clearance of aggresomes is not a universal phenomenon ESP Wong, JMM Tan, WE Soong, K Hussein, N Nukina, VL Dawson, ... Human molecular genetics 17 (16), 2570-2582, 2008 | 192 | 2008 |
| A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson’s disease models L Li, CW Zhang, GYJ Chen, B Zhu, C Chai, QH Xu, EK Tan, Q Zhu, KL Lim, ... Nature Communications 5 (1), 3276, 2014 | 191 | 2014 |
| AMP kinase activation mitigates dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson's disease CH Ng, MSH Guan, C Koh, X Ouyang, F Yu, EK Tan, SP O'Neill, X Zhang, ... Journal of Neuroscience 32 (41), 14311-14317, 2012 | 189 | 2012 |
| Deregulation of a STAT3–interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness N De La Iglesia, G Konopka, KL Lim, CL Nutt, JF Bromberg, DA Frank, ... Journal of Neuroscience 28 (23), 5870-5878, 2008 | 181 | 2008 |
| Role of the ubiquitin proteasome system in Parkinson's disease KL Lim, JMM Tan BMC biochemistry 8, 1-10, 2007 | 178 | 2007 |
| Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age AC Pawlyk, BI Giasson, DM Sampathu, FA Perez, KL Lim, VL Dawson, ... Journal of Biological Chemistry 278 (48), 48120-48128, 2003 | 177 | 2003 |
| Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases? KL Lim, VL Dawson, TM Dawson Neurobiology of aging 27 (4), 524-529, 2006 | 169 | 2006 |
