Neuroblastoma arginase activity creates an immunosuppressive microenvironment that impairs autologous and engineered immunity F Mussai, S Egan, S Hunter, H Webber, J Fisher, R Wheat, C McConville, ... Cancer research 75 (15), 3043-3053, 2015 | 109 | 2015 |
Selective inhibition of SIN3 corepressor with avermectins as a novel therapeutic strategy in triple-negative breast cancer YJ Kwon, K Petrie, BA Leibovitch, L Zeng, M Mezei, L Howell, V Gil, ... Molecular cancer therapeutics 14 (8), 1824-1836, 2015 | 78 | 2015 |
Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma E Poon, T Liang, Y Jamin, S Walz, C Kwok, A Hakkert, K Barker, Z Urban, ... The Journal of clinical investigation 130 (11), 5875-5892, 2020 | 46 | 2020 |
The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML M Kahl, A Brioli, M Bens, F Perner, A Kresinsky, U Schnetzke, A Hinze, ... Leukemia 33 (11), 2628-2639, 2019 | 35 | 2019 |
Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer N Bansal, K Petrie, R Christova, CY Chung, BA Leibovitch, L Howell, V Gil, ... Oncotarget 6 (33), 34087, 2015 | 34 | 2015 |
(Bio) printing in personalized medicine—opportunities and potential benefits D Shopova, A Yaneva, D Bakova, A Mihaylova, P Kasnakova, ... Bioengineering 10 (3), 287, 2023 | 26 | 2023 |
A colorectal cancer 3D bioprinting workflow as a platform for disease modeling and chemotherapeutic screening Y Sbirkov, D Molander, C Milet, I Bodurov, B Atanasov, R Penkov, N Belev, ... Frontiers in Bioengineering and Biotechnology 9, 755563, 2021 | 25 | 2021 |
Retinoic acid receptor γ is a therapeutically targetable driver of growth and survival in prostate cancer K Petrie, Z Urban‐Wójciuk, Y Sbirkov, A Graham, A Hamann, G Brown Cancer Reports 3 (6), e1284, 2020 | 23 | 2020 |
Autistic spectrum disorder (ASD)–Gene, molecular and pathway signatures linking systemic inflammation, mitochondrial dysfunction, transsynaptic signalling, and neurodevelopment M Gevezova, Y Sbirkov, V Sarafian, K Plaimas, A Suratanee, M Maes Brain, behavior, & immunity-health 30, 100646, 2023 | 19 | 2023 |
Alternative RNA splicing—The trojan horse of cancer cells in chemotherapy N Mehterov, M Kazakova, Y Sbirkov, B Vladimirov, N Belev, G Yaneva, ... Genes 12 (7), 1085, 2021 | 17 | 2021 |
Endothelial inflammation and dysfunction in COVID-19 Y Sbirkov, V Dzharov, K Todorova, S Hayrabedyan, V Sarafian Vasa, 2022 | 15 | 2022 |
Suppression of MYC by PI3K/AKT/mTOR pathway inhibition in combination with all‐trans retinoic acid treatment for therapeutic gain in acute myeloid leukaemia S Stengel, KR Petrie, Y Sbirkov, C Stanko, F Ghazvini Zadegan, V Gil, ... British Journal of Haematology 198 (2), 338-348, 2022 | 14 | 2022 |
Cellular bioenergetic and metabolic changes in patients with autism spectrum disorder M Gevezova, D Minchev, I Pacheva, Y Sbirkov, R Yordanova, E Timova, ... Current Topics in Medicinal Chemistry 21 (11), 985-994, 2021 | 10 | 2021 |
Semi-quantitative mass spectrometry in AML cells identifies new non-genomic targets of the EZH2 methyltransferase Y Sbirkov, C Kwok, A Bhamra, AJ Thompson, V Gil, A Zelent, K Petrie International journal of molecular sciences 18 (7), 1440, 2017 | 10 | 2017 |
World’s first long-term colorectal cancer model by 3D bioprinting as a mechanism for screening oncolytic viruses C McGuckin, N Forraz, C Milet, M Lacroix, Y Sbirkov, V Sarafian, C Ebel, ... Cancers 15 (19), 4724, 2023 | 7 | 2023 |
3D bioprinting as an emerging standard for cancer modeling and drug testing D Molander, Y Sbirkov, V Sarafian Folia Medica 64 (4), 559-565, 2022 | 6 | 2022 |
Metabolic reprogramming in childhood acute lymphoblastic leukemia Y Sbirkov, H Burnusuzov, V Sarafian Pediatric Blood & Cancer 67 (6), e28255, 2020 | 6 | 2020 |
Autophagy and SARS-CoV-2-old players in new games T Ivanova, Y Mariienko, N Mehterov, M Kazakova, Y Sbirkov, K Todorova, ... International Journal of Molecular Sciences 24 (9), 7734, 2023 | 4 | 2023 |
Dual inhibition of EZH2 and G9A/GLP histone methyltransferases by HKMTI-1-005 promotes differentiation of acute myeloid leukemia cells Y Sbirkov, T Schenk, C Kwok, S Stengel, R Brown, G Brown, L Chesler, ... Frontiers in Cell and Developmental Biology 11, 1076458, 2023 | 4 | 2023 |
The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme Z Urban-Wójciuk, A Graham, K Barker, C Kwok, Y Sbirkov, L Howell, ... Cancer gene therapy 29 (7), 940-950, 2022 | 4 | 2022 |