Directed evolution of artificial metalloenzymes for in vivo metathesis M Jeschek, R Reuter, T Heinisch, C Trindler, J Klehr, S Panke, TR Ward Nature 537 (7622), 661-665, 2016 | 446 | 2016 |
Rationally reduced libraries for combinatorial pathway optimization minimizing experimental effort M Jeschek, D Gerngross, S Panke Nature communications 7 (1), 11163, 2016 | 132 | 2016 |
Artificial metalloenzymes on the verge of new-to-nature metabolism M Jeschek, S Panke, TR Ward Trends in biotechnology 36 (1), 60-72, 2018 | 96 | 2018 |
E. coli surface display of streptavidin for directed evolution of an allylic deallylase T Heinisch, F Schwizer, B Garabedian, E Csibra, M Jeschek, ... Chemical science 9 (24), 5383-5388, 2018 | 95 | 2018 |
Combinatorial pathway optimization for streamlined metabolic engineering M Jeschek, D Gerngross, S Panke Current Opinion in Biotechnology 47, 142-151, 2017 | 95 | 2017 |
Chemo-enzymatic cascades to produce cycloalkenes from bio-based resources S Wu, Y Zhou, D Gerngross, M Jeschek, TR Ward Nature communications 10 (1), 5060, 2019 | 68 | 2019 |
Large-scale DNA-based phenotypic recording and deep learning enable highly accurate sequence-function mapping S Hoellerer, L Papaxanthos, AC Gumpinger, K Fischer, C Beisel, ... Nature Communications 11, 3551, 2020 | 52 | 2020 |
Systematic engineering of artificial metalloenzymes for new-to-nature reactions T Vornholt, F Christoffel, MM Pellizzoni, S Panke, TR Ward, M Jeschek Science Advances 7 (4), eabe4208, 2021 | 50 | 2021 |
Radical biocatalysis: Using non-natural single electron transfer mechanisms to access new enzymatic functions TK Hyster Synlett 31 (03), 248-254, 2020 | 46 | 2020 |
Biotin-independent strains of Escherichia coli for enhanced streptavidin production M Jeschek, MO Bahls, V Schneider, P Marlière, TR Ward, S Panke Metabolic engineering 40, 33-40, 2017 | 33 | 2017 |
The quest for xenobiotic enzymes: From new enzymes for chemistry to a novel chemistry of life T Vornholt, M Jeschek ChemBioChem 21 (16), 2241-2249, 2020 | 19 | 2020 |
Periplasmic screening for artificial metalloenzymes M Jeschek, S Panke, TR Ward Methods in enzymology 580, 539-556, 2016 | 16 | 2016 |
Ultradeep characterisation of translational sequence determinants refutes rare-codon hypothesis and unveils quadruplet base pairing of initiator tRNA and transcript S Höllerer, M Jeschek Nucleic Acids Research 51 (5), 2377-2396, 2023 | 9 | 2023 |
Rationally reduced libraries for combinatorial pathway optimization minimizing experimental effort. Nat Commun 7: 11163 M Jeschek, D Gerngross, S Panke | 6 | 2016 |
Enhanced Sequence-Activity Mapping and Evolution of Artificial Metalloenzymes by Active Learning T Vornholt, M Mutný, GW Schmidt, C Schellhaas, R Tachibana, S Panke, ... ACS Central Science, 2024 | 2 | 2024 |
From sequence to function and back–High-throughput sequence-function mapping in synthetic biology S Höllerer, C Desczyk, RF Muro, M Jeschek Current Opinion in Systems Biology, 100499, 2023 | 2 | 2023 |
Correction: E. coli surface display of streptavidin for directed evolution of an allylic deallylase T Heinisch, F Schwizer, B Garabedian, E Csibra, M Jeschek, ... Chemical science 10 (27), 6735-6735, 2019 | 1 | 2019 |
An Artificial Metalloenzyme for Atroposelective Metathesis T Vornholt, Z Jončev, V Sabatino, S Panke, TR Ward, C Sparr, M Jeschek ChemCatChem 15 (23), e202301113, 2023 | | 2023 |
Engineering Escherichia coli for non-natural metabolism M Jeschek ETH Zurich, 2016 | | 2016 |
Team: ETH Zurich/Team IML Seyfarth, GVDHS Kundert, SGDST Enke, S Panke, J Stelling, ... | | |