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Deregulation of DUX4 and ERG in acute lymphoblastic leukemia J Zhang, K McCastlain, H Yoshihara, B Xu, Y Chang, ML Churchman, ... Nature genetics 48 (12), 1481-1489, 2016 | 302 | 2016 |
Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy J Wei, L Long, W Zheng, Y Dhungana, SA Lim, C Guy, Y Wang, YD Wang, ... Nature 576 (7787), 471-476, 2019 | 300 | 2019 |
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Histone H3. 3 K27M accelerates spontaneous brainstem glioma and drives restricted changes in bivalent gene expression JD Larson, LH Kasper, BS Paugh, H Jin, G Wu, CH Kwon, Y Fan, TI Shaw, ... Cancer cell 35 (1), 140-155. e7, 2019 | 249 | 2019 |
The dynamic epigenetic landscape of the retina during development, reprogramming, and tumorigenesis I Aldiri, B Xu, L Wang, X Chen, D Hiler, L Griffiths, M Valentine, ... Neuron 94 (3), 550-568. e10, 2017 | 224 | 2017 |
MYC drives a subset of high-risk pediatric neuroblastomas and is activated through mechanisms including enhancer hijacking and focal enhancer amplification MW Zimmerman, Y Liu, S He, AD Durbin, BJ Abraham, J Easton, Y Shao, ... Cancer discovery 8 (3), 320-335, 2018 | 206 | 2018 |
Metabolic heterogeneity underlies reciprocal fates of TH 17 cell stemness and plasticity PWF Karmaus, X Chen, SA Lim, AA Herrada, TLM Nguyen, B Xu, ... Nature 565 (7737), 101-105, 2019 | 166 | 2019 |
Identification of therapeutic targets in rhabdomyosarcoma through integrated genomic, epigenomic, and proteomic analyses E Stewart, J McEvoy, H Wang, X Chen, V Honnell, M Ocarz, B Gordon, ... Cancer cell 34 (3), 411-426. e19, 2018 | 127 | 2018 |
Acute depletion of CTCF directly affects MYC regulation through loss of enhancer–promoter looping J Hyle, Y Zhang, S Wright, B Xu, Y Shao, J Easton, L Tian, R Feng, P Xu, ... Nucleic acids research 47 (13), 6699-6713, 2019 | 115 | 2019 |
Quantification of retinogenesis in 3D cultures reveals epigenetic memory and higher efficiency in iPSCs derived from rod photoreceptors D Hiler, X Chen, J Hazen, S Kupriyanov, PA Carroll, C Qu, B Xu, ... Cell stem cell 17 (1), 101-115, 2015 | 110 | 2015 |
Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia LE Montefiori, S Bendig, Z Gu, X Chen, P Pölönen, X Ma, A Murison, ... Cancer discovery 11 (11), 2846-2867, 2021 | 109 | 2021 |
MYCN amplification and ATRX mutations are incompatible in neuroblastoma M Zeineldin, S Federico, X Chen, Y Fan, B Xu, E Stewart, X Zhou, J Jeon, ... Nature communications 11 (1), 913, 2020 | 106 | 2020 |
H3. 3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo AB Silveira, LH Kasper, Y Fan, H Jin, G Wu, TI Shaw, X Zhu, JD Larson, ... Acta neuropathologica 137, 637-655, 2019 | 95 | 2019 |
Distinct roles of DNMT1-dependent and DNMT1-independent methylation patterns in the genome of mouse embryonic stem cells Z Li, H Dai, SN Martos, B Xu, Y Gao, T Li, G Zhu, DE Schones, Z Wang Genome biology 16, 1-15, 2015 | 94 | 2015 |
The Hippo pathway prevents YAP/TAZ-driven hypertranscription and controls neural progenitor number A Lavado, JY Park, J Pare, D Finkelstein, H Pan, B Xu, Y Fan, RP Kumar, ... Developmental cell 47 (5), 576-591. e8, 2018 | 93 | 2018 |
Fast and accurate computation schemes for evaluating vibrational entropy of proteins B Xu, H Shen, X Zhu, G Li Journal of computational chemistry 32 (15), 3188-3193, 2011 | 89 | 2011 |
Nucleome Dynamics during Retinal Development JL Norrie, MS Lupo, B Xu, I Al Diri, M Valentine, D Putnam, L Griffiths, ... Neuron 104 (3), 512-528. e11, 2019 | 79 | 2019 |
A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance S Dikiy, J Li, L Bai, M Jiang, L Janke, X Zong, X Hao, B Hoyos, ZM Wang, ... Immunity 54 (5), 931-946. e11, 2021 | 59 | 2021 |
An all‐atom knowledge‐based energy function for protein‐DNA threading, docking decoy discrimination, and prediction of transcription‐factor binding profiles B Xu, Y Yang, H Liang, Y Zhou Proteins: Structure, Function, and Bioinformatics 76 (3), 718-730, 2009 | 58 | 2009 |